Chemistry, Analysis, and Biological Roles ofS-Nitrosothiols

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

1996 • 1,604 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

1992 • 1,237 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Nitric oxide release from a single cell measured in situ by a porphyrinic-based microsensor

1992 • 1,063 citations

Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension

1991 • 1,062 citations

Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans

1991 • 960 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

Measurement of nitric oxide in biological models

1993 • 925 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

Simulation of the diffusion and reaction of endogenously produced nitric oxide.

1994 • 699 citations

Nitrate biosynthesis in man.

1981 • 677 citations

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.

1993 • 616 citations

Models of the diffusional spread of nitric oxide: Implications for neural nitric oxide signalling and its pharmacological properties

1994 • 517 citations

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated in the nitric oxide/oxygen reaction

1993 • 474 citations

An electrochemical microprobe for detecting nitric oxide release in brain tissue

1990 • 398 citations

Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione

1985 • 389 citations

Kinetics of Nitrosation of Thiols by Nitric Oxide in the Presence of Oxygen

1995 • 364 citations

Nitrosative Stress: Activation of the Transcription Factor OxyR

1996 • 351 citations

S‐nitroso‐glutathione inhibits platelet activation in vitro and in vivo

1992 • 330 citations

An unusually stable thionitrite from N-acetyl-D,L-penicillamine; X-ray crystal and molecular structure of 2-(acetylamino)-2-carboxy-1,1-dimethylethyl thionitrite

1978 • 281 citations

Vascular neuroeffector Mechanisms

1980 • 279 citations

Genetic and redox determinants of nitric oxide cytotoxicity in a Salmonella typhimurium model.

1995 • 250 citations

Biological activity of S-nitrosothiols: the role of nitric oxide.

1993 • 247 citations

The L-Arginine: Nitric Oxide Pathway Is the Major Source of Plasma Nitrite in Fasted Humans

1995 • 244 citations

Nitrite in Human Saliva. Its Possible Relationship to Nitrosamine Formation23

1974 • 240 citations

Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols.

1990 • 237 citations

Endothelium‐derived relaxing and contracting factors

1991 • 223 citations

Inhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty

1994 • 201 citations

A Rapid and Simple Method for the Measurement of Nitrite and Nitrate in Plasma by High Performance Capillary Electrophoresis

1994 • 198 citations

Direct Electrochemical Measurement of Nitric Oxide Released from Human Platelets

1993 • 196 citations

Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine.

1983 • 192 citations

Identification of Cu+ as the effective reagent in nitric oxide formation from S-nitrosothiols (RSNO)

1996 • 190 citations

Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine.

1990 • 190 citations

Homocysteine Antagonism of Nitric Oxide-Related Cytostasis in Salmonella typhimurium

1996 • 185 citations

Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation.

1983 • 184 citations

Decomposition ofS-Nitrosoglutathione in the Presence of Copper Ions and Glutathione

1996 • 176 citations

VISIBLE LIGHT PHOTOCHEMICAL RELEASE OF NITRIC OXIDE FROM S‐NITROSOGLUTATHIONE: POTENTIAL PHOTOCHEMOTHERAPEUTIC APPLICATIONS

1994 • 170 citations

Capillary zone electrophoretic detection of biological thiols and their S-nitrosated derivatives

1992 • 151 citations

Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro.

1994 • 151 citations

Metal ion catalysis in nitrosothiol (RSNO) decomposition

1993 • 147 citations

Determination of nitrite and nitrate in meat products

1963 • 137 citations

Catalysis by Cu2+ of nitric oxide release from S-nitrosothiols (RSNO)

1995 • 132 citations

Generation of nitric oxide from S-nitrosothiols using protein-bound Cu2+ sources

1996 • 128 citations

Vascular Neuroeffector Mechanisms

1984 • 125 citations

Copper chelation‐induced reduction of the biological activity of S‐nitrosothiols

1995 • 105 citations

Determination of trace levels of nitric oxide in aqueous solution

1980 • 104 citations

The relaxant properties in guinea pig airways of S-nitrosothiols.

1992 • 101 citations

Chemical mechanisms underlying the vasodilator and platelet anti-aggregating properties of S-nitroso-N-acetyl-dl-penicillamine and S-nitrosoglutathione

1995 • 96 citations

Direct comparison of the effects of nitroprusside, SIN 1, and various nitrates on platelet aggregation and soluble guanylate cyclase activity

1988 • 84 citations

Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure.

1991 • 81 citations

An investigation of some S‐nitrosothiols, and of hydroxy‐arginine, on the mouse anococcygeus

1992 • 79 citations

Microdetermination of nitrates and nitrites in saliva, blood, water, and suspended particulates in air by gas chromatography

1976 • 78 citations

Effect of LY 83583 on relaxation induced by non-adrenergic non-cholinergic nerve stimulation and exogenous nitric oxide in the rat gastric fundus

1992 • 74 citations

Preparation of some novel S-nitroso compounds as potential slow-release agents of nitric oxide in vivo

1994 • 62 citations

S-nitrosocysteine inhibition of human platelet secretion is correlated with increases in platelet cGMP levels.

1991 • 62 citations

Evidence That a S-Nitrosothiol, But Not Nitric Oxide, May Be Identical with Endothelium-Derived Relaxing Factor

1991 • 58 citations

NO-Group transfer (transnitrosation) between S-nitrosothiols and thiols. Part 2

1995 • 56 citations

Relative potency and arteriovenous selectivity of nitrovasodilators on human blood vessels: an insight into the targeting of nitric oxide delivery.

1995 • 54 citations

The reproducibility of the conversion of nitrate to nitrite in human saliva after a nitrate load

1988 • 51 citations

Comparative pharmacology of analogues of S‐nitroso‐N‐acetyl‐<scp>dl</scp>‐penicillamine on human platelets

1994 • 48 citations

Effects of ultraviolet radiation on the tension and the cyclic GMP level of bovine mesenteric arteries

1984 • 42 citations

Non‐adrenergic, non‐cholinergic relaxation of the bovine retractor penis muscle: role of S‐nitrosothiols

1994 • 42 citations

Kinetic studies on methemoglobin reduction by human red cell NADH cytochrome b5 reductase.

1979 • 35 citations

The thermal stability of S-nitrosothiols: experimental studies and ab initio calculations on model compounds

1997 • 34 citations

Photochemistry of the S-Nitroso Derivatives of Hexane-l-thiol and Hexane-l,6-dithiol

1966 • 33 citations

Repriming of Vascular Smooth Muscle Photorelaxation is Dependent upon Endothelium-derived Nitric Oxide

1995 • 32 citations

Interactions of Nitric Oxide and Redox-related species with biological targets

1995 • 29 citations

Über die thermische Dissoziation der Alkylthionitrite. III. Mitteilung über Thionitrite

1932 • 12 citations

Removal of Ammonia Interference in the Redox Chemiluminescence Assay of Nitric Oxide

1992 • 9 citations

Deleted Work

1955 • 0 citations

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