Active specific immunotherapy in malignant melanoma

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

T Cell Control of Antibody Production

1974 • 582 citations

Immunological factors which influence response to immunotherapy in malignant melanoma.

1970 • 462 citations

Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.

1975 • 434 citations

BCG lmmunotherapy of Malignant Melanoma

1974 • 430 citations

Demonstration of antibodies against human malignant melanoma by immunofluorescence.

1968 • 390 citations

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

1977 • 337 citations

Lymphokine regulation of activated (G1) lymphocytes. I. Prostaglandin E2-induced inhibition of interleukin 2 production.

1983 • 266 citations

Induction of cell-mediated immunity to autologous melanoma cells and regression of metastases after treatment with a melanoma cell vaccine preceded by cyclophosphamide.

1986 • 255 citations

Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2.

1982 • 242 citations

Active specific immunotherapy for melanoma: phase I trial of allogeneic lysates and a novel adjuvant.

1988 • 239 citations

Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients.

1987 • 224 citations

Ganglioside GM2 as a human tumor antigen (OFA-I-1).

1983 • 174 citations

Gangliosides of Human Melanoma2

1987 • 161 citations

Modulation of Suppressor-Cell Activity by Cimetidine in Patients with Common Variable Hypogammaglobulinemia

1985 • 141 citations

Augmentation of the human immune response by cyclophosphamide.

1982 • 136 citations

Potentiation of human cell-mediated and humoral immunity by low-dose cyclophosphamide.

1984 • 124 citations

Hapten-specific IgE antibody responses in mice. VI. Selective enhancement of IgE antibody production by low doses of X-irradiation and by cyclophosphamide.

1976 • 117 citations

Cooperation between cyclophosphamide tumoricidal activity and host antitumor immunity in the cure of mice bearing large MOPC-315 tumors.

1981 • 100 citations

Inhibition of T suppressor cell expression by histamine type 2 (H2) receptor antagonists.

1984 • 96 citations

Human melanoma antigen O-acetylated ganglioside GD3 is recognized by Cancer antennarius lectin.

1988 • 81 citations

Contrasting effects of cyclophosphamide and prednisolone on the phenotype of human peripheral blood leukocytes

1983 • 68 citations

Clinical improvement in advanced cancer disease after treatment combining histamine and H2-antihistaminics (ranitidine or cimetidine)

1988 • 66 citations

Tolerance and contact sensitivity to DNFB in mice. VI. Inhibition of afferent sensitivity by suppressor T cells in adoptive tolerance.

1976 • 64 citations

Serological response of melanoma patients to vaccines prepared from VSV lysates of autologous and allogeneic cultured melanoma cells

1985 • 61 citations

Cyclophosphamide eliminates suppressor T cells in age-associated central regulation of delayed hypersensitivity in mice.

1979 • 56 citations

PRELIMINARY RESULTS OF A RANDOMIZED TRIAL OF ADJUVANT IMMUNOTHERAPY IN PATIENTS WITH MALIGNANT MELANOMA WHO HAVE LYMPH NODE METASTASES

1978 • 45 citations

Serological responses of melanoma patients to vaccines derived from allogeneic cultured melanoma cells

1983 • 44 citations

Active immunotherapy against cancer: present status.

1986 • 39 citations

Mechanism of histamine-induced inhibition of lymphocyte response to mitogens in mice

1981 • 36 citations

Suppressor cell activity in melanoma patients. I. Relation to tumor growth and immunoglobulin levels in vivo

1981 • 33 citations

Immunochemical characterization of fetal antigen isolated from spent medium of a human melanoma cell line.

1983 • 27 citations

Prostaglandins and the immune response to cancer (review).

1981 • 27 citations

Serologic response to human melanoma lines from patients with melanoma undergoing treatment with vaccinia melanoma oncolysates.

1984 • 26 citations

Antigen mediation of a late-acting suppressor T-cell activity.

1977 • 25 citations

Autologous cellular immune response to primary and metastatic human melanomas and its regulation by DR antigens expressed on tumor cells

1985 • 25 citations

Studies of a Melanoma Tumor-Associated Antigen Detected in the Spent Culture Medium of a Human Melanoma Cell Line by Allogeneic Antibody. III. Physicochemical Properties23

1984 • 22 citations

Comparison of approaches for augmenting the serologic response to the individually specific methylcholanthrene-induced sarcoma-Meth A: pretreatment with cyclophosphamide is most effective.

1983 • 21 citations

Studies of a Melanoma Tumor-Associated Antigen Detected in the Spent Culture Medium of a Human Melanoma Cell Line by Allogeneic Antibody. I. Purification and Development of a Radioimmunoassay23

1984 • 19 citations

Studies of a Melanoma Tumor-Associated Antigen Detected in the Spent Culture Medium of a Human Melanoma Cell Line by Allogeneic Antibody. II. Immunobiologic Characterization23

1984 • 14 citations

Recovery of a cell surface fetal antigen from circulating immune complexes of melanoma patients

1988 • 14 citations

Oncofoetal antigen I: a target for immune cytolysis of human cancer

1979 • 13 citations

Prognostic significance of urinary antigen analysis by enzyme-linked immunosorbent assay in melanoma patients.

1983 • 9 citations

Characteristics of histamine receptors present on suppressor T cells in “healthy individuals”

1985 • 9 citations

Suppressor T-cell function in man: Suppression of immunoglobulin production by the direct action of immunoregulatory T cells on the B cell in four separate, distinct systems

1982 • 8 citations

Specific chemoimmunotherapy in tumor-bearing mice with extracted antigen, cyclophosphamide, and intrasplenic administration of interleukin-2

1986 • 7 citations

Book ReviewHealth Care of the Female Adolescent

1985 • 1 citations