Ineffective expression of CD40 ligand on cord blood T cells may contribute to poor immunoglobulin production in the newborn

Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes.

1992 • 1,259 citations

Molecular and biological characterization of a murine ligand for CD40

1992 • 1,029 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1993 • 840 citations

CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome

1993 • 836 citations

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1993 • 739 citations

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1993 • 719 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

1991 • 554 citations

A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

1989 • 527 citations

The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

1992 • 518 citations

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells.

1990 • 453 citations

Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion.

1992 • 409 citations

Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

1991 • 406 citations

Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM.

1993 • 372 citations

Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes.

1992 • 358 citations

Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen.

1991 • 334 citations

Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3.

1994 • 330 citations

Cloning of TRAP, a ligand for CD40 on human T cells

1992 • 280 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Induction of Plasma Cell Differentiation of Human Fetal Lymphocytes: Evidence for Functional Immaturity of T and B Cells

1977 • 174 citations

Novel immunoregulatory functions of phenotypically distinct subpopulations of CD4+ cells in the human neonate.

1990 • 142 citations

Immunoregulatory role of CD40 in human B cell differentiation.

1993 • 122 citations

B Cell Differentiation and Immunoregulatory T Cell Function in Human Cord Blood Lymphocytes

1980 • 120 citations

Cytokine regulation of immunoglobulin secretion by neonatal lymphocytes.

1991 • 88 citations

T helper cell‐dependent B cell activation

1991 • 84 citations

Identification of a source of biologically active CD40 ligand

1992 • 81 citations

Expression of a 32‐kDa ligand for the CD40 antigen on activated human T lymphocytes

1993 • 65 citations

Are cord blood B cells functionally mature?

1991 • 61 citations

Immunology of the neonate

1990 • 43 citations

The role of functionally distinct helper T lymphocyte subpopulations in the inductionof human B cell differentiation

1990 • 36 citations

Monocyte-regulated Hyporesponsiveness of Human Cord Blood Lymphocytes to OKT3-monoclonal-antibody-induced Mitogenesis

1986 • 31 citations