Huntington's Disease: Update and Review of Neuropsychiatric Aspects

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

1993 • 7,941 citations

The American Journal of Human Genetics

1950 • 5,048 citations

Neuropathological Classification of Huntingtonʼs Disease

1985 • 2,517 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Frontal-Subcortical Circuits and Human Behavior

1993 • 2,248 citations

Caudate Glucose Metabolic Rate Changes With Both Drug and Behavior Therapy for Obsessive-Compulsive Disorder

1992 • 1,283 citations

New England Journal of Medicine

2010 • 647 citations

Psychiatric Developments

1945 • 475 citations

The Psychological Consequences of Predictive Testing for Huntington’s Disease

1992 • 467 citations

Cerebral metabolism and atrophy in huntington's disease determined by ¹⁸FDG and computed tomographic scan

1982 • 449 citations

Morphometric Demonstration of Atrophic Changes in the Cerebral Cortex, White Matter, and Neostriatum in Huntington's Disease

1988 • 414 citations

Neurobehavioral changes associated with caudate lesions

1989 • 396 citations

Procedural learning is impaired in Huntington's disease: Evidence from the serial reaction time task

1991 • 384 citations

Differential Patterns of Memory Loss Among Patients With Alzheimer's Disease, Huntington's Disease, and Alcoholic Korsakoff's Syndrome

1986 • 338 citations

The epidemiology of Huntington's disease

1992 • 326 citations

Huntington's disease : a disorder of families

1989 • 324 citations

Psychiatric Aspects of Neurological Disease

1976 • 323 citations

Explicit Memory in Alzheimer's, Huntington's, and Parkinson's Diseases

1993 • 313 citations

Reduced Cerebral Glucose Metabolism in Asymptomatic Subjects at Risk for Huntington's Disease

1987 • 309 citations

PET scan investigations of Huntington's disease: Cerebral metabolic correlates of neurological features and functional decline

1986 • 268 citations

Dissociations Between Skill Learning and Verbal Recognition in Amnesia and Dementia

1984 • 268 citations

Increased rate of suicide among patients with Huntington's disease.

1984 • 259 citations

Psychiatric syndromes in Huntington's disease

1983 • 258 citations

Suicide and attempted suicide in Huntington disease: Implications for preclinical testing of persons at risk

1986 • 245 citations

Huntington disease

1981 • 224 citations

The association of affective disorder with Huntington's Disease in a case series and in families

1983 • 223 citations

Clinical and neuropathologic assessment of severity in Huntington's disease

1988 • 213 citations

Abnormal ocular motor control in Huntington's disease

1983 • 213 citations

Are all subcortical dementias Alike?: Verbal learning and memory in Parkinson's and huntington's disease patients

1990 • 211 citations

Paralimbic frontal lobe hypometabolism in depression associated with Huntington's disease

1992 • 197 citations

Clinical Assessment of Irritability, Aggression, and Apathy in Huntington and Alzheimer Disease

1990 • 189 citations

Huntington's Dementia

1978 • 188 citations

Socio-Psychiatric Consequences of Huntington's Disease

1970 • 186 citations

Differential Perceptual-Spatial Impairment in Huntington's and Alzheimer's Dementias

1984 • 182 citations

Huntington's disease in Venezuela

1986 • 182 citations

Development of Neuropsychological Deficits in Huntington's Disease

1983 • 171 citations

Nocturnal sleep in huntington's disease

1991 • 165 citations

Differential cognitive impairment in alzheimer's disease and huntington's disease

1988 • 165 citations

Obsessive-compulsive disorder in Huntington's disease

1992 • 165 citations

Huntington's disease

1984 • 165 citations

Positron emission tomographic scan investigations of Huntington's disease: Cerebral metabolic correlates of cognitive function

1988 • 163 citations

The neuropsychology of Huntington's disease

1986 • 155 citations

An outline for the analysis of dementia

1977 • 150 citations

Semantic fluency in Alzheimer's, Parkinson's, and Huntington's disease: Dissociation of storage and retrieval failures.

1993 • 144 citations

Presymptomatic Diagnosis of Delayed-Onset Disease With Linked DNA Markers

1989 • 142 citations

Chemical Pathology of Huntington's Disease

1980 • 133 citations

Conduct disorder and affective disorder among the offspring of patients with Huntington's Disease

1983 • 128 citations

The clinical aspects of memory disorders: Contributions from experimental studies of amnesia and dementia

1984 • 124 citations

Clinical‐pathologic correlation in Huntington's disease

1989 • 120 citations

LANGUAGE FUNCTIONS IN HUNTINGTON'S DISEASE

1988 • 113 citations

Conditions Associated With Huntington's Disease at Death

1988 • 111 citations

A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease

1990 • 110 citations

The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's disease

1987 • 109 citations

Huntington's Chorea in Northamptonshire

1970 • 107 citations

Neuropsychological and neuroradiological correlates in Huntington's disease.

1988 • 107 citations

Huntington's Chorea in the West of Scotland

1970 • 105 citations

A controlled clinical trial of baclofen as protective therapy in early huntington's disease

1989 • 104 citations

Sleep disturbances and severity of Huntington's disease

1985 • 97 citations

Duration of illness in Huntington's disease is not related to age at onset.

1993 • 97 citations

Pictorial priming and cued recall in Alzheimer's and Huntington's disease

1990 • 90 citations

Presymptomatic Neuropsychological Impairment in Huntington's Disease

1988 • 90 citations

Differentiation of Alzheimer's Disease and Huntington's Disease With the Dementia Rating Scale

1989 • 90 citations

Comprehension of prosody in Huntington's disease.

1990 • 89 citations

Verbal memory errors in Alzheimer's and Huntington's dementias

1988 • 89 citations

The diagnostic utility of savings scores: Differentiating Alzheimer's and Huntington's diseases with the logical memory and visual reproduction tests

1993 • 88 citations

Normal Caudate Glucose Metabolism in Persons at Risk for Huntington's Disease

1987 • 87 citations

Prefrontal cortical blood flow and cognitive function in Huntington's disease.

1988 • 87 citations

NEUROPSYCHOLOGICAL AND EMOTIONAL CORRELATES OF HUNTINGTON??S CHOREA

1974 • 84 citations

Visuospatial cognition in Huntington's disease

1991 • 83 citations

Ideomotor Apraxia in Huntington's Disease

1991 • 76 citations

What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies

1990 • 76 citations

Cognitive and Motor Correlates of Everyday Functioning in Early Huntington??s Disease

1993 • 74 citations

Evidence of presymptomatic cognitive decline in Huntington's disease

1992 • 71 citations

Is verbal recognition memory really different in Huntington's and Alzheimer's disease?

1992 • 68 citations

Memory failure in huntington's disease

1987 • 68 citations

The biasing of weight judgments in Alzheimer's and Huntington's disease: A priming or programming phenomenon?

1991 • 61 citations

The nucleus basalis in Huntington's disease

1983 • 60 citations

Prism adaptation in Alzheimer's and Huntington's disease.

1993 • 59 citations

The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD.

1993 • 58 citations

A note on spatial-motor deficits in patients with Huntington's Disease: A test of a hypothesis

1971 • 58 citations

Huntington's Chorea in South Wales A genetic and epidemiological study

1981 • 57 citations

Correlates of early disability in Huntington's disease

1986 • 55 citations

Clozapine treatment of psychiatric symptoms resistant to neuroleptic treatment in patients with Huntington's chorea

1991 • 52 citations

Are There Neuropsychologic Manifestations of the Gene for Huntington's Disease in Asymptomatic, At-Risk Individuals?

1990 • 52 citations

Neurolinguistic characteristics of language production in Huntington's disease: A preliminary report

1987 • 48 citations

Psychiatric, Genetic, and Positron Emission Tomographic Evaluation of Persons at Risk for Huntington's Disease

1992 • 45 citations

Unimpaired Verbal Memory and Oculomotor Control in Asymptomatic Adults With the Genetic Marker for Huntington's Disease

1993 • 43 citations

D2 receptors in Huntington's disease: positron emission tomography findings and clinical correlates

1990 • 43 citations

Presymptomatic Testing for Huntington's Disease in Wales 1987–90

1992 • 39 citations

Premorbid psychometric indicators of the gene for Huntington's disease.

1977 • 38 citations

Huntington’s disease as a model for mood disorders

1990 • 36 citations

Clinical and experimental neurology

1984 • 34 citations

Huntington's chorea in Norway

1986 • 34 citations

A comparison of the frequency of major affective disorder in Huntington's disease and Alzheimer's disease.

1985 • 33 citations

Cerebral Blood Flow and Cognitive Testing Correlate in Huntington's Disease

1985 • 32 citations

The Coexistence and Differentiation of Late Onset Huntington's Disease and Alzheimer's Disease: A Case Report and Review of the Literature

1988 • 31 citations

Attempt at preclinical identification of huntington's disease using the WAIS

1986 • 31 citations

Aspects of procedural memory are differentially impaired in huntington's disease

1990 • 30 citations

Aggressive behavior in Huntington's disease: treatment with propranolol.

1987 • 27 citations

Personal and Extrapersonal Orientation in Huntington's Disease Patients and those at Risk

1992 • 26 citations

Psychiatric morbidity associated with early clinical diagnosis of Huntington disease in a predictive testing program.

1988 • 24 citations

A Blinded Study of the Suppressibility of Involuntary Movements in Huntingtonʼs Chorea, Tardive Dyskinesia, and L-DOPA-Induced Chorea

1990 • 19 citations

A follow‐up study of isolated cases of suspected Huntington's disease

1992 • 19 citations

Dementia: A Clinical Approach, 2nd Edition

1994 • 16 citations

Psychological features of Huntington's disease and the problem of early detection

1980 • 14 citations

Affective psychopathology in Huntington's Disease: the Johns Hopkins hypothesis and German psychiatry

1984 • 8 citations

The Role of the Caudate in Nonmotor Behaviors in Huntington’s Disease

1992 • 5 citations

Thirteen years longitudinal study of computed tomography, visual electrophysiology and neuropsychological changes in Huntington's chorea patients and 50% at-risk asymptomatic subjects.

1990 • 2 citations