Evaluation of the dependence potential of the selective 5-H1A agonist ipsapirone in rats and of its effects on benzodiazepine withdrawal

II. New evidence for a locus coeruleus-norepinephrine connection with anxiety

1979 • 666 citations

5-HT1A receptor-related anxiolytics

1987 • 402 citations

Buspirone

1986 • 330 citations

Abuse liability of benzodiazepines.

1987 • 313 citations

Single administration of 5-HT1A agonists decreases 5-HT1A presynaptic, but not postsynaptic receptor-mediated responses: relationship to antidepressant-like action

1987 • 173 citations

8-OH-DPAT-induced hyperphagia: Its neural basis and possible therapeutic relevance

1986 • 167 citations

Hypothermia induced by the putative 5-HT1A agonists LY165163 and 8-OH-DPAT is not prevented by 5-HT depletion

1987 • 121 citations

Buspirone, a new approach to the treatment of anxiety

1988 • 104 citations

The history of benzodiazepine dependence: A review of animal studies

1990 • 100 citations

Effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT

1987 • 96 citations

Comparison of Buspirone and Diazepam in Generalized Anxiety Disorder

1985 • 83 citations

Failure of buspirone to manage benzodiazepine withdrawal

1986 • 80 citations

Changing concepts of the biochemical action of the anxioselective drug, buspirone

1984 • 75 citations

Gepirone in anxiety: a pilot study.

1987 • 72 citations

A Double-Blind Placebo-Controlled Study of Buspirone in Diazepam Withdrawal in Chronic Benzodiazepine Users

1990 • 66 citations

The effects of ondansetron (GR38032F) in rats and mice treated subchronically with diazepam

1989 • 59 citations

Behavioral effects of several new anxiolytics and putative anxiolytics

1987 • 57 citations

Changes in noradrenaline plasma levels and behavioural responses induced by benzodiazepine agonists with the benzodiazepine antagonist Ro 15-1788

1986 • 55 citations

The 5-HT1A agonist 8-OH-DPAT increases consumption of palatable wet mash and liquid diets in the rat

1988 • 54 citations

Buspirone enhances benzodiazepine receptor binding in vivo

1988 • 53 citations

Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats

1990 • 51 citations

Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines

1987 • 49 citations

Gepirone in Anxiety

1987 • 49 citations

Interaction of buspirone and dopaminergic agents on punished behavior of pigeons

1986 • 48 citations

Experimental Psychopharmacology

1987 • 47 citations

The interoceptive discriminative stimuli induced by the novel putative anxiolytic TVX Q 7821: behavioral evidence for the specific involvement of serotonin 5-HT1A receptors

1987 • 43 citations

Conditioned taste aversion and place preference with buspirone and gepirone

1990 • 39 citations

Measures of anxiety and stress in the rat following chronic treatment with yohimbine

1988 • 39 citations

Chronic diazepam treatment in rats causes long‐lasting changes in central [³H]‐5‐hydroxytryptamine and [¹⁴C]‐γ‐aminobutyric acid release

1990 • 38 citations

Clinical profile of gepirone, a nonbenzodiazepine anxiolytic.

1988 • 36 citations

Reversal by alpha-2 agonists of diazepam withdrawal hyperactivity in rats

1986 • 35 citations

Effect of the 5-HT1A receptor agonist ipsapirone on the local cerebral glucose utilization of the rat hippocampus

1987 • 33 citations

Aversive Stimulus Properties of Drugs

1987 • 29 citations

Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity

1989 • 23 citations

Ipsapirone and 1-(2-pyrimidinyl)-piperazine increase rat locus coeruleus noradrenergic activity

1990 • 23 citations

Monoamine metabolism during chronic benzodiazepine treatment and withdrawal.

1983 • 19 citations

Lack of Withdrawal Signs of Dependence following Cessation of Treatment or Ro-15,1788 Administration to Rats Chronically Treated with Buspirone

1986 • 14 citations

Tolerance to the behavioural effects of the selective 5-HT1A agent, ipsapirone

1989 • 9 citations

Deleted Work

1955 • 0 citations