Progesterone can participate in down-regulation of the luteinizing hormone receptor gene expression and function in cultured murine Leydig cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.

1975 • 932 citations

The Lutropin/Choriogonadotropin Receptor… 4 Years Later*

1993 • 394 citations

Direct Inhibitory Effect of Glucocorticoids upon Testicular Luteinizing Hormone Receptor and Steroidogenesisin Vivoandin Vitro*

1981 • 360 citations

Endocrine Regulation and Communicating Functions of the Leydig Cell

1988 • 267 citations

Reporter constructs with low background activity utilizing the cat gene

1992 • 240 citations

Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity.

1990 • 237 citations

Control of transcription activation by steroid hormone receptors

1992 • 218 citations

The induction of oocyte maturation: transmembrane signaling events and regulation of the cell cycle

1989 • 189 citations

Establishing the minimum effective dose and additive effects of depot progestin in suppression of human spermatogenesis by a testosterone depot.

1996 • 154 citations

Treatment of Prostatic Cancer with a Gonadotropin-Releasing Hormone Agonist Analog: Acute and Long Term Effects on Endocrine Functions of Testis Tissue*

1985 • 152 citations

Structural organization of the rat luteinizing hormone (LH) receptor gene

1991 • 151 citations

A pitfall of using a second plasmid to determine transfection efficiency

1992 • 150 citations

Establishment of gonadotropin-responsive murine leydig tumor cell line.

1982 • 145 citations

Regulation of the progesterone receptor gene by gonadotropins and cyclic adenosine 3',5'-monophosphate in rat granulosa cells.

1994 • 138 citations

An enzymatic solid-phase method for trace iodination of proteins and peptides with 125iodine

1975 • 130 citations

Lutropin/choriogonadotropin down-regulates its receptor by both receptor-mediated endocytosis and a cAMP-dependent reduction in receptor mRNA.

1991 • 120 citations

Glucocorticoid receptors in interstitial cells of the rat testis

1976 • 118 citations

Regulation of Luteinizing Hormone Receptor Messenger Ribonucleic Acid Levels by Gonadotropins, Growth Factors, and Gonadotropin-Releasing Hormone in Cultured Rat Granulosa Cells*

1991 • 108 citations

Localization of the glucocorticoid receptor in testis and accessory sexual organs of male rat

1993 • 104 citations

Hormonal regulation of androgen production by the Leydig cell

1984 • 99 citations

Evidence that Human Chorionic Gonadotropin/Luteinizing Hormone Receptor Down-Regulation Involves Decreased Levels of Receptor Messenger Ribonucleic Acid*

1991 • 93 citations

The murine luteinizing hormone and follicle-stimulating hormone receptor genes: Transcription initiation sites, putative promoter sequences and promoter activity

1992 • 92 citations

On the Structure of the Luteinizing Hormone/Chorionic Gonadotropin Receptor*

1989 • 86 citations

Suppression of endogenous corticosterone levels in vivo increases the steroidogenic capacity of purified rat Leydig cells in vitro.

1996 • 83 citations

Regulation of Luteinizing-Hormone-Receptors and Steroidogenesis in the Neonatal Rat Testis

1981 • 79 citations

Progesterone ”Receptor“ in Rat Ovary*

1979 • 75 citations

Establishing the minimum effective dose and additive effects of depot progestin in suppression of human spermatogenesis by a testosterone depot

1996 • 74 citations

Progesterone receptor, but not estradiol receptor, messenger ribonucleic acid is expressed in luteinizing granulosa cells and the corpus luteum in rhesus monkeys.

1994 • 72 citations

Biphasic Increase in c-jun mRNA Is Required for Induction of AP-1-Mediated Gene Transcription: Differential Effects of Muscarinic and Thrombin Receptor Activation

1992 • 71 citations

Daily measurements of salivary progesterone reveal a high rate of anovulation in healthy students

1989 • 67 citations

Androgen and progesterone receptors in shark (Squalus) testis: characteristics and stage-related distribution.

1992 • 58 citations

The 5'-flanking region of the rat luteinizing hormone/chorionic gonadotropin receptor gene confers Leydig cell expression and negative regulation of gene transcription by 3',5'-cyclic adenosine monophosphate.

1992 • 53 citations

Persistent expression of a truncated form of the luteinizing hormone receptor messenger ribonucleic acid in the rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate.

1994 • 50 citations

Regulation of the progesterone receptor gene by gonadotropins and cyclic adenosine 3',5'-monophosphate in rat granulosa cells

1994 • 48 citations

Epidermal growth factor, a phorbol ester, and 3',5'-cyclic adenosine monophosphate decrease the transcription of the luteinizing hormone/chorionic gonadotropin receptor gene in MA-10 Leydig tumor cells.

1992 • 45 citations

Evidence for a human ovarian progesterone receptor

1980 • 43 citations

Homologous Regulation of Hormone Receptors: Luteinizing Hormone Increases Its Own Receptors in Cultured Rat Granulosa Cells*

1984 • 43 citations

Two mutations of the lutropin/choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis.

1996 • 42 citations

Progesterone regulation of luteinizing hormone receptors on cultured bovine luteal cells

1992 • 42 citations

Dimerization characteristics of the DNA- and steroid-binding domains of the androgen receptor

1994 • 41 citations

Biphasic increase in c-jun mRNA is required for induction of AP-1-mediated gene transcription: differential effects of muscarinic and thrombin receptor activation.

1992 • 40 citations

Immunohistological determination of oestrogen receptor, progesterone receptor, and intermediate filaments in Leydig cell tumours, Leydig cell hyperplasia, and normal Leydig cells of the human testis

1989 • 39 citations

Induction of Granulosa Cell Differentiation by Forskolin: Stimulation of Adenosine 3′,5′-Monophosphate Production, Progesterone Synthesis, and Luteinizing Hormone Receptor Expression

1984 • 36 citations

Suppression of endogenous corticosterone levels in vivo increases the steroidogenic capacity of purified rat Leydig cells in vitro

1996 • 35 citations

Stimulation of testosterone production by atrial natriuretic peptide in isolated mouse Leydig cells results from a promiscuous activation of cyclic AMP-dependent protein kinase by cyclic GMP

1992 • 34 citations

Progesterone receptor, but not estradiol receptor, messenger ribonucleic acid is expressed in luteinizing granulosa cells and the corpus luteum in rhesus monkeys

1994 • 33 citations

Adult rat Leydig cell cultures: Minimum requirements for maintenance of luteinizing hormone responsiveness and testosterone production

1992 • 32 citations

Differences in the Regulation of Steroidogenesis and Tropic Hormone Receptors between the Scrotal and Abdominal Testes of Unilaterally Cryptorchid Adult Rats

1984 • 29 citations

Luteolytic action of two antiprogestational agents (RU-38486 and ZK-98734) in the rat

1988 • 28 citations

Characterization of cytoplasmic progesterone receptors in rat granulosa cells. Evidence for nuclear translocation

1981 • 26 citations

Mitochondrial Cholesterol Availability during Gonadotropin-Induced Leydig Cell Desensitization

1985 • 24 citations

Regulation of function of the murine luteinizing hormone receptor promoter by cis- and trans-acting elements in mouse Leydig tumor cells

1996 • 24 citations

Persistent expression of a truncated form of the luteinizing hormone receptor messenger ribonucleic acid in the rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate

1994 • 24 citations

Androgen and progesterone receptors in shark (Squalus) testis: characteristics and stage-related distribution

1992 • 23 citations

Two mutations of the lutropin/choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis

1996 • 19 citations

Gonadotropin interactions with the gonad as assessed by receptor binding and adenylyl cyclase activity.

1977 • 19 citations

Epidermal growth factor, a phorbol ester, and 3',5'-cyclic adenosine monophosphate decrease the transcription of the luteinizing hormone/chorionic gonadotropin receptor gene in MA-10 Leydig tumor cells

1992 • 14 citations

Evidence for a Leydig cell progesterone receptor in the rat

1988 • 12 citations

Adrenocortical steroidogenesis and aminoglutethimide I. Biomedical studies.

1973 • 10 citations

Inhibition of Adrenal Cortical Secretion by Amino-glutethimide in Dogs¹

1968 • 9 citations

Differential c-jun gene expression with tonically administered steroids in rat ovary and uterus

1994 • 5 citations