Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro.

Rapid generation of functional human IgG antibodies derived from Fab-on-phage display libraries.

2004 • 2,484 citations

Phage antibodies: filamentous phage displaying antibody variable domains

1990 • 2,346 citations

Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex Lesions

1981 • 1,242 citations

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

1991 • 1,178 citations

Genital Herpes Simplex Virus Infections: Clinical Manifestations, Course, and Complications

1983 • 921 citations

Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms.

1992 • 824 citations

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

1991 • 662 citations

A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cells

1988 • 514 citations

Acyclovir-Resistant Herpes Simplex Virus Infections in Patients with the Acquired Immunodeficiency Syndrome

1989 • 470 citations

Herpes Simplex Virus Resistant to Acyclovir

1990 • 357 citations

Risk of Recurrence after First Episodes of Genital Herpes

1981 • 348 citations

Molecular Profile of an Antibody Response to HIV-1 as Probed by Combinatorial Libraries

1993 • 229 citations

Protection against lethal challenge of BALB/c mice by passive transfer of monoclonal antibodies to five glycoproteins of herpes simplex virus type 2

1982 • 215 citations

Neutralizing antibodies specific for glycoprotein H of herpes simplex virus permit viral attachment to cells but prevent penetration

1989 • 201 citations

Cellular Immunity and Herpesvirus Infections in Cardiac-Transplant Patients

1977 • 189 citations

Excretion of Non-infectious Virus Particles Lacking Glycoprotein H by a Temperature-sensitive Mutant of Herpes Simplex Virus Type 1: Evidence that gH Is Essential for Virion Infectivity

1988 • 185 citations

Progressive Esophagitis from Acyclovir-Resistant Herpes Simplex

1989 • 183 citations

Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.

1993 • 164 citations

Use of monoclonal antibody directed against herpes simplex virus glycoproteins to protect mice against acute virus-induced neurological disease

1981 • 157 citations

Specificities of monoclonal and polyclonal antibodies that inhibit adsorption of herpes simplex virus to cells and lack of inhibition by potent neutralizing antibodies

1985 • 140 citations

Rapid Identification of Nonessential Genes of Herpes Simplex Virus Type 1 by Tn5 Mutagenesis

1987 • 130 citations

Humanized antibodies for antiviral therapy.

1991 • 126 citations

Identification of Patients with Increased Risk of Infection with Herpes Simplex Virus after Renal Transplantation

1979 • 121 citations

A Comparative Study of Herpes Simplex Infections in Renal Transplant and Leukemic Patients

1987 • 111 citations

Role of antibody in primary and recurrent herpes simplex virus infection

1985 • 111 citations

Interactions of Antibodies, Complement Components and Various Cell Types in Immunity Against Viruses and Pyogenic Bacteria

1974 • 110 citations

Pathogenesis of Herpes Simplex Virus in Congenitally Athymic Mice: the Relative Roles of Cell-mediated and Humoral Immunity

1982 • 96 citations

Domains of herpes simplex virus I glycoprotein B that function in virus penetration, cell-to-cell spread, and cell fusion

1992 • 89 citations

Passive immune protection by herpes simplex virus-specific monoclonal antibodies and monoclonal antibody-resistant mutants altered in pathogenicity

1985 • 79 citations

The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy

1991 • 74 citations

Analysis of the IgM and IgG antibody response against herpes simplex virus type 1 (HSV‐1) structural and nonstructural proteins

1987 • 55 citations

Recombinant human antibodies: linkage of an Fab fragment from a combinatorial library to an Fc fragment for expression in mammalian cell culture

1993 • 52 citations

Monoclonal antibodies suppress replication of herpes simplex virus type 1 in trigeminal ganglia

1984 • 43 citations

Antiviral Activities of Human Monoclonal Antibodies to Herpes Simplex Virus

1987 • 24 citations

Identification of Infected Cell-specific Monoclonal Antibodies and their Role in Host Resistance to Ocular Herpes Simplex Virus Type 1 Infection

1984 • 20 citations

Visceral Herpesvirus Infections in Leukemic Patients Receiving Cytarabine

1980 • 8 citations