Cellular events in the evolution of experimental diabetic nephropathy

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Practical Nonparametric Statistics

2000 • 11,073 citations

Secretory products of macrophages.

1987 • 2,670 citations

Practical Non-Parametric Statistics.

1981 • 2,559 citations

Practical Nonparametric Statistics (2nd ed).

1981 • 1,909 citations

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation.

1986 • 1,644 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

USRDS 2004 annual data report

2005 • 1,087 citations

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

1992 • 984 citations

Advanced Glycosylation End Products in Patients with Diabetic Nephropathy

1991 • 925 citations

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy.

1993 • 819 citations

Glomerular hemodynamics in experimental diabetes mellitus

1981 • 785 citations

Hemodynamically mediated glomerular injury and the progressive nature of kidney disease

1983 • 607 citations

Thromboxane Biosynthesis and Platelet Function in Type II Diabetes Mellitus

1990 • 600 citations

The kinetics of antibody binding to membrane antigens in solution and at the cell surface

1980 • 568 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Renal injury from angiotensin II-mediated hypertension.

1992 • 546 citations

Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy.

1985 • 532 citations

Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle

1986 • 529 citations

Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.

1990 • 500 citations

Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation.

1991 • 461 citations

Mesangial Expansion as a Central Mechanism for Loss of Kidney Function in Diabetic Patients

1989 • 414 citations

Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model

1992 • 404 citations

Transforming growth factor-β regulates production of proteoglycans by mesangial cells

1990 • 365 citations

High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-β

1992 • 353 citations

Increased Sodium-Lithium Countertransport Activity in Red Cells of Patients with Insulin-Dependent Diabetes and Nephropathy

1988 • 348 citations

Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor.

1992 • 345 citations

The Role of Macrophages in Diabetic Glomerulosclerosis

1993 • 312 citations

The laminin B2 chain has a multidomain structure homologous to the B1 chain.

1987 • 307 citations

mRNA Expression of Growth Factors in Glomeruli From Diabetic Rats

1993 • 300 citations

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

1991 • 293 citations

cDNA cloning by PCR of rat transforming growth factor β-1

1990 • 274 citations

Enhanced expression of “muscle-specific” actin in glomerulonephritis

1992 • 268 citations

Increased synthesis of extracellular matrix in mesangial proliferative nephritis

1991 • 265 citations

Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy.

1991 • 243 citations

Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells.

1989 • 235 citations

The activated mesangial cell

1992 • 219 citations

Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA

1988 • 210 citations

Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat.

1990 • 191 citations

Glucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cells.

1992 • 184 citations

Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis

1993 • 170 citations

Glomerular lesions in mice transgenic for growth hormone and insulinlike growth factor-I. I. Relationship between increased glomerular size and mesangial sclerosis.

1990 • 168 citations

Renal hypertrophy in experimental diabetes mellitus

1983 • 164 citations

T-cells and macrophages in rapidly progressive glomerulonephritis: Clinicopathologic correlations

1987 • 159 citations

Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo.

1993 • 143 citations

Rat glomerular mesangial cells synthesize basic fibroblast growth factor. Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis.

1992 • 136 citations

Structural-functional correlations of diabetic nephropathy

1994 • 133 citations

ECM gene expression and its modulation by insulin in diabetic rats

1992 • 123 citations

Phenotypic Expression of Collagen Types in Mesangial Matrix of Diabetic and Nondiabetic Rats

1988 • 120 citations

Evidence for Existence of Polyol Pathway in Cultured Rat Mesangial Cells

1987 • 115 citations

Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40

1987 • 114 citations

Demonstration of PDGF B-chain mRNA in glomeruli in mesangial proliferative nephritis by in situ hybridization

1991 • 110 citations

Diabetes-induced glomerular dysfunction: Links to a more reduced cytosolic ratio of NADH/NAD+

1992 • 105 citations

Dietary protein restriction rapidly reduces transforming growth factor beta 1 expression in experimental glomerulonephritis.

1991 • 96 citations

Platelets mediate neutrophil-dependent immune complex nephritis in the rat.

1988 • 95 citations

Glomerulosclerosis in mice transgenic for growth hormone. Increased mesangial extracellular matrix is correlated with kidney mRNA levels.

1991 • 92 citations

Mesangiolysis

1983 • 90 citations

Transforming Growth Factor-β1 Enhances Glomerular Collagen Synthesis in Diabetic Rats

1993 • 85 citations

Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis.

1984 • 84 citations

Selective Depletion of Rat Neutrophils by In Vivo Administration of a Monoclonal Antibody

1989 • 82 citations

Functional and morphological renal manifestations in diabetes mellitus

1981 • 82 citations

Heterogeneous distribution of a basement membrane heparan sulfate proteoglycan in rat tissues.

1987 • 76 citations

Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo

1989 • 72 citations

Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen.

1987 • 70 citations

Increased steady-state levels of laminin B1 mRNA in kidneys of long-term streptozotocin-diabetic rats. No effect of an aldose reductase inhibitor.

1988 • 69 citations

Changes in renal function in response to protein restricted diet in Type 1 (insulin-dependent) diabetic patients

1987 • 68 citations

Renal hypertrophy, growth factors, and nephropathy in diabetes mellitus.

1990 • 59 citations

Studies on human migration inhibitory factor: characterization of three molecular species.

1981 • 57 citations

Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73–97 fragment of its B-chain

1989 • 55 citations

Relationship of glomerular hypertrophy and sclerosis: Studies in SV40 transgenic mice

1990 • 54 citations

Relationship Between Renal Function and Metabolic Alterations in Early Streptozocin-Induced Diabetes in Rats

1987 • 52 citations

Transcriptional activity of the alpha 1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro.

1991 • 51 citations

Platelet-Inhibitor Treatment of Diabetic Nephropathy: A 10-Year Prospective Study

1988 • 42 citations

Platelets in inflammatory glomerular injury.

1991 • 41 citations

Does extracellular matrix expansion in glomerular disease require mesangial cell proliferation?

1994 • 38 citations

Macrophages and cellular immunity in experimental glomerulonephritis

1982 • 35 citations

A monoclonal antibody against rat platelets. I. Tissue distribution in vitro and in vivo.

1989 • 31 citations

Prevalence of raised sodium-lithium countertransport activity in type 1 diabetic patients

1992 • 30 citations

Streptozotocin-induced renal hemodynamic changes in isogenic Lewis rats: a kidney transplant study

1993 • 13 citations

Radioimmunoassay of Human Platelet-Derived Growth Factor Using Monoclonal Antibody Toward a Synthetic 73-97 Fragment of its B-Chain

1989 • 12 citations

Carbohydrates as recognition molecules in macrophage activities.

1989 • 10 citations

Elevated Levels of Plasma and Urine Beta-Thromboglobulin or Thromboxane-B<sub>2</sub> as Markers of Real Platelet Hyperactivation in Diabetic Nephropathy

1992 • 6 citations