HIV-1 Neutralizing Monoclonal Antibodies Induced by a Synthetic Peptide

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

1978 • 2,726 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

1964 • 820 citations

In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity

1988 • 754 citations

[29] Enzyme-linked immunoelectrotransfer blot techniques (EITB) for studying the specificities of antigens and antibodies separated by gel electrophoresis

1983 • 698 citations

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

1988 • 626 citations

Major Glycoprotein Antigens That Induce Antibodies in AIDS Patients Are Encoded by HTLV-III

1985 • 583 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

1988 • 514 citations

Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions

1987 • 443 citations

A Formalin-Inactivated Whole SIV Vaccine Confers Protection in Macaques

1989 • 419 citations

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

1988 • 417 citations

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

1988 • 412 citations

Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG

1979 • 411 citations

Neutralization of the AIDS Retrovirus by Antibodies to a Recombinant Envelope Glycoprotein

1986 • 362 citations

HTLV-III/LAV-Neutralizing Antibodies to anE. coli-Produced Fragment of the Virus Envelope

1986 • 336 citations

[8] Use of glutaraldehyde as a coupling agent for proteins and peptides

1980 • 313 citations

Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins

1987 • 301 citations

Variable and conserved neutralization antigens of human immunodeficiency virus

1986 • 296 citations

Second Conserved Domain of gp120 Is Important for HIV Infectivity and Antibody Neutralization

1988 • 242 citations

Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibody.

1986 • 238 citations

Induction of anti-HIV neutralizing antibodies by synthetic peptides.

1986 • 237 citations

An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies

1989 • 222 citations

Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.

1987 • 220 citations

Immunoassay for the detection and quantitation of infectious human retrovirus, lymphadenopathy-associated virus (LAV)

1985 • 208 citations

Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoprotein.

1986 • 204 citations

Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees

1987 • 197 citations

A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS

1988 • 183 citations

Characteristics of a Neutralizing Monoclonal Antibody to the HIV Envelope Glycoprotein

1988 • 139 citations

Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells.

1987 • 138 citations

Generation and characterization of monoclonal antibodies to the putative CD4-binding domain of human immunodeficiency virus type 1 gp120

1989 • 129 citations

Neutralizing monoclonal antibodies to the AIDS virus

1988 • 124 citations

Specificity and Function of the Individual Amino Acids of an Important Determinant of Human Immunodeficiency Virus Type 1 that Induces Neutralizing Activity

1989 • 82 citations

Antibodies from Human Immunodeficiency Virus-Infected Individuals Bind to a Short Amino Acid Sequence that Elicits Neutralizing Antibodies in Animals

1989 • 62 citations

Monoclonal Antibodies that Neutralize HIV–1 Virions and Inhibit Syncytium Formation by Infected Cells

1987 • 37 citations

The production of more useful monoclonal antibodies I. Modifications of the basic technology

1986 • 32 citations

Characterization of Murine Monoclonal Antibodies to HIV-1 Induced by Synthetic Peptides

1988 • 14 citations

Fine Molecular Specificity of Linear and Assembled Antibody Binding Sites in HIV‐1 p24

1991 • 12 citations

Tissue distribution, immunochemical characterization, and biosynthesis of 47D10, a tumor-associated surface glycoprotein.

1987 • 9 citations