Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Polyamine metabolism and function

1982 • 1,649 citations

Esters of Methanesulfonic Acid as Irreversible Inhibitors of Acetylcholinesterase

1962 • 1,510 citations

Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose

1970 • 1,349 citations

Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs

1978 • 998 citations

Polyamines in Biology and Medicine

1982 • 446 citations

Selective inhibitors of biosynthesis of aminergic neurotransmitters

1978 • 424 citations

Enzyme-Activated Irreversible Inhibitors

1979 • 420 citations

Polyamine Metabolism: A Potential Therapeutic Target in Trypanosomes

1980 • 379 citations

Advances in polyamine research

1978 • 369 citations

Chemotherapeutic implications of polyamine biosynthesis inhibition

1984 • 235 citations

Catalytic inhibition of γ-aminobutyric acid-α-ketoglutarate transaminase of bacterial origin by 4-aminohex-5-ynoic acid, a substrate analog

1975 • 136 citations

In vivo effects of α-dl-Difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei

1983 • 135 citations

Suicide enzyme inhibitors as potential drugs

1981 • 119 citations

.alpha.-(Fluoromethyl)dehydroornithine and .alpha.-(fluoromethyl)dehydroputrescine analogs as irreversible inhibitors of ornithine decarboxylase

1983 • 100 citations

Restriction of bacterial growth by inhibition of polyamine biosynthesis by using monofluoromethylornithine, difluoromethylarginine and dicyclohexylammonium sulphate

1982 • 64 citations

Synthesis and Content of Polyamines in Bloodstream Trypanosoma brucei*

1979 • 51 citations

(2R,5R)-6-heptyne-2,5-diamine, an extremely potent inhibitor of mammalian ornithine decarboxylase

1983 • 41 citations

α-monofluoromethyl and α-difluoromethyl putrescine as ornithine decarboxylase inhibitors: In vitro and in vivo biochemical properties

1982 • 36 citations

DL-α-Monofluoromethylputrescine is a potent irreversible inhibitor of Escherichia coli ornithine decarboxylase

1982 • 33 citations

Uptake of α-difluoromethylornithine by mouse fibroblasts

1982 • 30 citations

Ornithine Decarboxylase in Trypanosoma brucei brucei: Evidence for Selective Toxicity of Difluoromethylornithine¹

1982 • 24 citations