Catecholaminergic mechanisms of reinforcement: Direct assessment by drug self-administration

Evidence for dopamine receptor stimulation by apomorphine

1967 • 910 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

Possible Etiology of Schizophrenia: Progressive Damage to the Noradrenergic Reward System by 6-Hydroxydopamine

1971 • 480 citations

Both Positive Reinforcement and Conditioned Aversion from Amphetamine and from Apomorphine in Rats

1976 • 307 citations

Methods in narcotics research

1975 • 221 citations

Intracranial self-stimulation with electrodes in the region of the locus coeruleus

1972 • 215 citations

Dopaminergic and Noradrenergic Substrates of Positive Reinforcement: Differential Effects of d - and l -Amphetamine

1973 • 197 citations

ET495 and brain catecholamine mechanisms: Evidence for stimulation of dopamine receptors

1972 • 176 citations

Adrenergic receptor blocking agents: Effects on central noradrenaline and dopamine receptors and on motor activity

1974 • 160 citations

On the mode of action of apomorphine

1973 • 152 citations

Evidence for a new type of dopamine receptor stimulating agent

1971 • 152 citations

Self-injection of apomorphine in the rat: Positive reinforcement by a dopamine receptor stimulant

1974 • 147 citations

Evidence of -noradrenergic reward receptors and serotonergic punishment receptors in the rat brain.

1973 • 141 citations

Neurochemical mediation of reward: A significant role for dopamine?

1973 • 127 citations

Effect of apomorphine on motility in rats

1972 • 111 citations

Hypothalamic self-stimulation: Its suppression by blockade of norepinephrine biosynthesis and reinstatement by methamphetamine

1966 • 99 citations

Effect of haloperidol on (+)-amphetamine self-administration

1975 • 95 citations

Noradrenergic role in the self-administration of morphine or amphetamine

1975 • 94 citations

Central catecholamine turnover and self-stimulation behaviour

1971 • 91 citations

Effect of 6‐hydroxydopamine on electrical self stimulation of the brain

1971 • 79 citations

A comparison of effects of apomorphine and ET495 on locomotor activity and circling behaviour in mice☆

1974 • 68 citations

The site and mode of action of ET495 for the mediation of stereotyped behaviour in the rat

1973 • 58 citations

Effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-stimulation in the rat

1970 • 54 citations

Blocking of morphine based reinforcement by alpha-methyltyrosine

1973 • 52 citations

Blocking effect of α-methyltyrosine on amphetamine based reinforcement

1973 • 49 citations

The effects of 6-Hydroxydopamine, Dopamine and dl-Norepinephrine on food intake and water consumption, self-stimulation, temperature and electroencephalographic activity in the rat

1973 • 39 citations

Dissociation of the analgesic and rewarding effects of brain stimulation in the rat

1973 • 37 citations

Alpha-methyltyrosine to prevent self-administration of morphine and amphetamine.

1972 • 37 citations

Decreased septal-forebrain and lateral hypothalamic reward after alpha methyl-p-tyrosine

1971 • 36 citations

Effects of apomorphine on exploration

1972 • 29 citations

Apomorphine self-injection is not affected by alpha-methylparatyrosine treatment: Support for dopaminergic reward

1976 • 25 citations

Effects of ?-methyl-p-tyrosine on morphine dependence

1973 • 15 citations

Effects of various inhibitors of tyrosine hydroxylase and dopamine beta-hydroxylase on rat self-stimulation after reserpine treatment

1976 • 15 citations

Effects of α‐methyl‐p‐tyrosine and <scp>l</scp>‐DOPA on brain self‐stimulation and motor activity in rats

1973 • 5 citations