The vitamin D—induced differentiation of HL-60 cells: Structural requirements

Vitamin D

1979 • 3,814 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

Vitamin D ₃ -Induced Calcium-Binding Protein in Chick Intestinal Mucosa

1966 • 740 citations

Target Cells for 1,25-Dihydroxyvitamin D ₃ in Intestinal Tract, Stomach, Kidney, Skin, Pituitary, and Parathyroid

1979 • 713 citations

1,25-Dihydroxycholecalciferol: A Potent Stimulator of Bone Resorption in Tissue Culture

1972 • 631 citations

Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide.

1979 • 602 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

1,25-DIHYDROXYVITAMIN D₃AND MALIGNANT MELANOMA: THE PRESENCE OF RECEPTORS AND INHIBITION OF CELL GROWTH IN CULTURE

1981 • 560 citations

1,25-Dihydroxyvitamin D ₃ : a Novel Immunoregulatory Hormone

1984 • 536 citations

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

1983 • 500 citations

Regulation of Terminal Differentiation of Cultured Mouse Epidermal Cells by lα,25-Dihydroxyvitamin D₃*

1983 • 468 citations

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells.

1984 • 461 citations

1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells

1981 • 460 citations

VITAMIN D: RECENT ADVANCES

1983 • 437 citations

1α,25-Dihydroxycholecalciferol and a human myeloid leukaemia cell line (HL-60)

1982 • 398 citations

Isolation and identification of 24,25-dihydroxycholecalciferol, a metabolite of vitamin D3 made in the kidney

1972 • 331 citations

Osteoclasts derived from haematopoietic stem cells

1980 • 320 citations

1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukaemia (HL60) cells and induces monocyte-macrophage differentiation in HL60 and normal human bone marrow cells

1983 • 307 citations

Influence of sodium on calcium transport by the rat small intestine

1969 • 284 citations

1α,25-Dihydroxycholecalciferol Receptors in Intestine

1974 • 279 citations

Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues.

1984 • 236 citations

γ-interferon stimulates production of 1,25-dihydroxyvitamin D3 by normal human macrophages

1985 • 232 citations

Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1 alpha,25-dihydroxycholecalciferol.

1983 • 215 citations

1α,25-Dihyroxyvitamin D3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocyte-macrophages, but not into granulocytes

1983 • 206 citations

Interactions of 1,25-dihydroxyvitamin D3 and the immune system

1985 • 181 citations

The role of 1,25-dihydroxyvitamin D3 and parathyroid hormone in the regulation of chick renal 25-hydroxyvitamin D3-24-hydroxylase

1975 • 175 citations

1,25-Dihydroxycholecalciferol: Metabolite of Vitamin D ₃ Active on Bone in Anephric Rats

1972 • 171 citations

Circulating 25-hydroxyvitamin D in man

1974 • 170 citations

Equilibrium binding of estradiol by uterine cell suspensions and whole uteri in vitro

1974 • 169 citations

Mechanism of Action and Metabolic Fate of Vitamin D

1967 • 168 citations

Appearance of the intestinal cytosolic receptor for 1,25-dihydroxyvitamin D3 during neonatal development in the rat.

1981 • 144 citations

Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

1984 • 144 citations

Specific cytosol-binding protein for 1,25-dihydroxyvitamin D3 in rat intestine.

1977 • 141 citations

Presence of 1,25-dihydroxyvitamin D3 receptors in established human cancer cell lines in culture.

1982 • 136 citations

Structural requirements for the interaction of 1 alpha, 25-(OH) 2- vitiamin D3 with its chick interestinal receptor system.

1975 • 132 citations

1,25-Dihydroxycholecalciferol Stimulates Osteoclasts in Rat Bones in the Absence of Parathyroid Hormone*

1981 • 127 citations

Receptor-mediated release of plasma membrane-associated calcium and stimulation of calcium uptake by thyrotropin-releasing hormone in pituitary cells in culture.

1981 • 113 citations

25-Hydroxyvitamin D3 26,23-lactone: a new in vivo metabolite of vitamin D

1979 • 112 citations

Vitamin D3 from rat skins irradiated in vitro with ultraviolet light

1978 • 110 citations

Biological activity of 24,24-difluoro-25-hydroxyvitamin D3. Effect of blocking of 24-hydroxylation on the functions of vitamin D.

1979 • 106 citations

No 1,25-dihydroxyvitamin D3 receptors on osteoclasts of calcium-deficient chicken despite demonstrable receptors on circulating monocytes.

1986 • 105 citations

Vitamin D ₃ —Resistant Fibroblasts Have Immunoassayable 1,25-Dihydroxyvitamin D ₃ Receptors

1984 • 87 citations

Intestinal 1,25-dihydroxyvitamin D3 binding protein: Specificity of binding

1977 • 87 citations

1,25-Dihydroxyvitamin D3 increases bone alkaline phosphatase isoenzyme levels in human osteogenic sarcoma cells.

1983 • 86 citations

Biological activity of 1,25-dihydroxyvitamin D₂ in the chick

1976 • 80 citations

Evidence for a 1,25-dihydroxyvitamin D3 receptor-like macromolecule in rat pituitary.

1980 • 73 citations

Regulation of prolactin mRNA by 1,25-dihydroxyvitamin D3 in GH4C1 cells.

1983 • 66 citations

Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus.

1983 • 64 citations

Vitamin D Stimulation of [³H]Orotic Acid Incorporation into Ribonucleic Acid of Rat Intestinal Mucosa^*

1967 • 63 citations

Subcellular Location of Vitamin D and Its Metabolites in Intestinal Mucosa after a 10-IU Dose^*

1967 • 61 citations

19-Nor-10-ketovitamin D derivatives: unique metabolites of vitamin D3, vitamin D2, and 25-hydroxyvitamin D3

1983 • 58 citations

Phenotypic differentiation-linked growth inhibition in human leukemia cells by active vitamin D3 analogues

1984 • 55 citations

Reversibility of Vitamin D-Induced Human Leukemia Cell-Line Maturation*

1986 • 54 citations

Biological activity of 24,24-difluoro-1α,25-dihydroxyvitamin D3 and 1α,25-dihydroxyvitamin D3-26,23-lactone in inducing Differentiation of human myeloid leukemia cells

1983 • 48 citations

1,25-Dihydroxyvitamin D3 inhibits selectively the mitogenic stimulation of mouse medullary thymocytes

1984 • 46 citations

The Tissue Localization of Tritiated Parathyroid Hormone in Thyroparathyroidectomized Rats

1972 • 41 citations

Induction of a high phagocytic capability in P388D1, a macrophage-like tumor cell line, by 1 alpha, 25-dihydroxyvitamin D3.

1984 • 40 citations

Biological activity of 1α,24‐dihydroxycholecalciferol; A new synthetic analog of the hormonal form of vitamin D

1977 • 40 citations

Synthesis of 1β-hydroxyvitamin D₃and 1β,25-dihydroxyvitamin D₃

1977 • 33 citations

Production of 10-oxo-19-nor-25-hydroxyvitamin D3 by solubilized kidney mitochondria from chick and rat.

1985 • 31 citations

Incorporation of oxygen-18 into the 25-position of cholecalciferol by hepatic cholecalciferol 25-hydroxylase

1978 • 31 citations

Mechanism of action of 1,25-dihydroxyvitamin D3-induced stimulation of alkaline phosphatase in cultured osteoblast-like cells

1983 • 31 citations

CALCIFICATION OF RACHITIC BONES IN VITRO

1925 • 30 citations

1,25-Dihydroxyvitamin D3 receptors in a subset of mitotically active lymphocytes from rat thymus

1984 • 30 citations

Inhibition by 1 alpha, 25-dihydroxyvitamin D3 of induction of epidermal ornithine decarboxylase caused by 12-O-tetradecanoylphorbol-13-acetate and teleocidin B.

1984 • 29 citations

Receptor for 1,25-Dihydroxyvitamin D3 in GH3 pituitary cells

1982 • 28 citations

25-Hydroxy-26,26,26,27,27,27-hexafluorovitamin D3: Biological activity in the rat

1982 • 27 citations

Metabolism of 25-hydroxyvitamin D3 by rat kidney cells in culture: Isolation and identification of cis- and trans-19-nor-10-oxo-25-hydroxyvitamin D3

1984 • 27 citations

Functional Defect of Variant Clones of a Human Myeloid Leukemia Cell Line (HL-60) Resistant to lα,25- Dihydroxyvitamin D₃*

1983 • 26 citations

Regulation of 25-hydroxyvitamin D3 metabolism in a human promyelocytic leukemia cell line (HL-60): 1,25-Dihydroxyvitamin D3 stimulates the synthesis of 24,25-dihydroxyvitamin D3

1986 • 25 citations

The early time course of calcium-binding protein induction by 1,25-dihydroxyvitamin D3 as determined by computer analysis of two-dimensional electrophoresis gels.

1984 • 23 citations

Mechanism of the differentiating action of 25-hydroxyvitamin D3 endoperoxides in human myeloid leukemia cells (HL-60)

1985 • 21 citations

Syntheses and differentiating action of vitamin D endoperoxides. Singlet oxygen adducts of vitamin D derivatives in human myeloid leukemia cells (HL-60)

1985 • 21 citations

Biological activities and binding properties of 23,23-difluoro-25-hydroxyvitamin D3 and its 1α-hydroxy derivative

1985 • 20 citations

Human myeloid leukemia cells metabolize 25-hydroxyvitamin D3invitro

1985 • 17 citations

1α,25‐Dihydroxyvitamin D₃ directly induces fusion of alveolar macrophages by a mechanism involving RNA and protein synthesis, but not DNA synthesis

1984 • 17 citations

Inhibition by 1α, 25-dihydroxyvitamin D3 of dimethyl sulfoxide-induced differentiation of friend erythroleukemia cells

1984 • 9 citations

Low-temperature physics: Knudsen effects in liquid helium

1983 • 2 citations