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Drug-Induced Nephrotoxicity Aetiology, Clinical Features and Management

Data up to Jan 2025

Published1991
Citations93
References134

Total Citations Per Year

Abstract

References (134)

Case 39-2000

2000 • 3,891 citations

Hospital-acquired renal insufficiency: A prospective study

1983 • 1,227 citations

Cyclosporine-Associated Chronic Nephropathy

1984 • 1,174 citations

Renal Syndromes Associated with Nonsteroidal Antiinflammatory Drugs

1984 • 1,098 citations

CYCLOSPORIN A IN PATIENTS RECEIVING RENAL ALLOGRAFTS FROM CADAVER DONORS

1978 • 1,010 citations

Contrast Material-Induced Renal Failure in Patients with Diabetes Mellitus, Renal Insufficiency, or Both

1989 • 1,006 citations

Captopril-Induced Functional Renal Insufficiency in Patients with Bilateral Renal-Artery Stenoses or Renal-Artery Stenosis in a Solitary Kidney

1983 • 658 citations

Dosing of contrast material to prevent contrast nephropathy in patients with renal disease

1989 • 545 citations

Contrast Nephrotoxicity: A Randomized Controlled Trial of a Nonionic and an Ionic Radiographic Contrast Agent

1989 • 415 citations

Renal Histopathologic Alterations in Patients Treated with Cyclosporine for Uveitis

1986 • 350 citations

Effects of Sulindac and Ibuprofen in Patients with Chronic Glomerular Disease

1984 • 334 citations

Nephrotoxicity of contrast media

1989 • 306 citations

IMMUNE-COMPLEX GLOMERULOPATHY IN PATIENTS TREATED WITH CAPTOPRIL

1980 • 305 citations

Nephrotoxicity Induced by Cancer Chemotherapy With Special Emphasis on Cisplatin Toxicity

1986 • 301 citations

HLA-DR Antigens and Toxic Reaction to Sodium Aurothiomalate and D-Penicillamine in Patients with Rheumatoid Arthritis

1980 • 295 citations

Comparison of Captopril and Enalapril in Patients with Severe Chronic Heart Failure

1986 • 293 citations

Acute Interstitial Nephritis Due to Drugs

1980 • 278 citations

Acute interstitial nephritis due to methicillin

1978 • 268 citations

CYCLOSPORIN IN THERAPEUTIC DOSES INCREASES RENAL ALLOGRAFT VASCULAR RESISTANCE

1986 • 265 citations

Analgesic Use and Chronic Renal Disease

1989 • 251 citations

Reversible Renal Failure and Nephrotic Syndrome Associated with Nonsteroidal Anti-Inflammatory Drugs

1979 • 221 citations

Aminoglycoside nephrotoxicity

1988 • 214 citations

Functional Renal Insufficiency During Long-Term Therapy with Captopril and Enalapril in Severe Chronic Heart Failure

1987 • 212 citations

Prevention of Amphotericin B—Induced Renal Impairment

1988 • 195 citations

Prevention of Radiocontrast-Media-Induced Nephrotoxicity by the Calcium Channel Blocker Nitrendipine: A Prospective Randomised Clinical Trial

1989 • 194 citations

ACUTE RENAL TOXICITY WITH COMBINED USE OF AMPHOTERICIN B AND CYCLOSPORINE AFTER MARROW TRANSPLANTATION

1983 • 162 citations

A role for calcium in radiocontrast-induced reductions in renal hemodynamics

1985 • 157 citations

Adverse Effects of <scp>D</scp>-Penicillamine in Rheumatoid Arthritis

1980 • 155 citations

Pharmacokinetic Drug Interactions with Cyclosporin (Part I)1

1990 • 154 citations

Acute Interstitial Nephritis: A Clinical and Morphological Study in 27 Patients

1990 • 152 citations

Characteristics of Response of Renal Vascular Bed to Contrast Media

1970 • 147 citations

Reversible Acute Renal Failure from Combined Triamterene and Indomethacin

1982 • 139 citations

Gold nephropathy a clinical and pathologic study

1970 • 133 citations

Fenoprofen nephropathy: Lipoid nephrosis and interstitial nephritis

1982 • 132 citations

NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND RENAL FAILURE

1986 • 131 citations

Risk factors for amphotericin B-associated nephrotoxicity

1989 • 126 citations

Calcium is a competitive inhibitor of gentamicin-renal membrane binding interactions and dietary calcium supplementation protects against gentamicin nephrotoxicity.

1984 • 124 citations

Morphological patterns in cyclosporine-treated renal transplant recipients.

1985 • 119 citations

Cyclosporin treatment for rheumatoid arthritis: a placebo controlled, double blind, multicentre study.

1986 • 114 citations

Regular Analgesic Intake and the Risk of End-Stage Renal Failure

1989 • 112 citations

Allergic Interstitial Nephritis Causing Reversible Renal Failure in Four Patients with Idiopathic Nephrotic Syndrome

1973 • 107 citations

Acute Effects of Captopril on Systemic and Renal Hemodynamics and on Renal Function in Cirrhotic Patients With Ascites

1985 • 106 citations

A Model for Predicting Nephrotoxicity in Patients Treated with Aminoglycosides

1986 • 106 citations

Allergic Interstitial Nephritis: Clinical Features and Pathogenesis

1988 • 104 citations

Proteinuria During Long-term Captopril Therapy

1980 • 101 citations

Nonsteroidal Anti-inflammatory Drug Nephrotoxicity

1990 • 101 citations

Heroin nephropathy

1980 • 99 citations

Membranous Glomerulonephritis Associated with Industrial Mercury Exposure:Study of Pathogenetic Mechanisms

1982 • 93 citations

Acute Interstitial Nephritis: Immunologic and Clinical Aspects

1988 • 92 citations

Effects of prolonged administration of d-penicillamine or captopril in various strains of rats

1984 • 88 citations

NEPHROTIC SYNDROME IN HEROIN ADDICTS

1972 • 85 citations

Gold nephropathy prototype of membranous glomerulonephritis.

1974 • 85 citations

Mechanism of the Renal Response to Contrast Medium in Dogs

1983 • 82 citations

Triamterene Nephrolithiasis

1980 • 74 citations

Nephrotic Syndrome After Contact with Mercury

1962 • 71 citations

Acute renal failure secondary to oral ciprofloxacin therapy: a presentation of three cases and a review of the literature.

1989 • 71 citations

Indomethacin-associated acute renal failure

1980 • 70 citations

Studies of Risk Factors for Aminoglycoside Nephrotoxicity

1986 • 70 citations

EXACERBATION OF CYCLOSPORINE TOXICITY BY CONCOMITANT ADMINISTRATION OF ERYTHROMYCIN

1987 • 70 citations

Systemic Lupus Erythematosus Occurring During Anticonvulsive Drug Therapy

1962 • 69 citations

Drug Nephrotoxicity

1988 • 69 citations

Acute interstitial nephritis associated with thiazide diuretics

1980 • 67 citations

Contrast Media-Induced Nephrotoxicity

1985 • 65 citations

Adverse Reactions and Interactions of Cyclosporin

1988 • 61 citations

Renal insufficiency with combinations of angiotensin converting enzyme inhibitors and diuretics.

1984 • 60 citations

Drug-induced acute interstitial nephritis with granulomas

1983 • 59 citations

CYCLOSPORIN TREATMENT WITH CONVERSION AFTER THREE MONTHS VERSUS CONVENTIONAL IMMUNOSUPPRESSION IN RENAL ALLOGRAFT RECIPIENTS

1987 • 58 citations

Cyclosporin-erythromycin interaction in normal subjects.

1987 • 58 citations

Acute interstitial nephritis due to drug hypersensitivity. An up-to-date review with a report of 19 cases.

1983 • 56 citations

Toxicity of Penicillamine

1978 • 56 citations

Role of tubular obstruction in acute renal failure due to gentamicin

1983 • 53 citations

Renal Insufficiency Associated With Nonsteroidal Anti-inflammatory Agents

1984 • 52 citations

The nephrotic syndrome as a complication of gold therapy

1970 • 51 citations

Aminoglycoside nephrotoxicity in obstructive jaundice

1988 • 51 citations

Minimal-Change Disease and the Nephrotic Syndrome Associated with Lithium Therapy

1980 • 51 citations

Heavy Metal Poisoning: Mercury and Lead

1972 • 49 citations

Nephrotoxicity of Common Drugs Used in Clinical Practice-Reply

1988 • 49 citations

Immunopathology of penicillamine-induced glomerular disease.

1984 • 43 citations

Suprofen-Related Nephrotoxicity

1987 • 43 citations

Penicillamine in Rheumatoid Arthritis: Adverse Effects

1979 • 42 citations

Amyloidosis in Chronic Heroin Addicts with the Nephrotic Syndrome

1979 • 41 citations

The development and resolution of glomerular basement membrane changes associated with subepithelial immune deposits.

1975 • 41 citations

Nephrotic Syndrome Induced by Tolmetin

1981 • 40 citations

Gold nephropathy. Ultrastructural, fluorescence, and microanalytic studies of two patients.

1976 • 40 citations

Membranous glomerulopathy associated with captopril therapy

1983 • 40 citations

Tubular Nephrotoxicity after Intravenous Urography with Ionic High-Osmolal and Nonionic Low-Osmolal Contrast Media in Patients with Chronic Renal Insufficiency

1987 • 38 citations

Glomerular morphology in nephrotic heroin addicts.

1976 • 37 citations

Sodium Protects Against Nephrotoxicity in Patients Receiving Amphotericin B

1989 • 35 citations

Effects of Nonsteroidal Antiinflammatory Drugs on Renal Function in Patients With Renal Insufficiency and in Cirrhotics

1986 • 32 citations

An appraisal of drug interactions with Sandimmun.

1989 • 32 citations

Severe nephrotoxicity caused by the combined use of gentamicin and cyclosporine in renal allograft recipients.

1986 • 32 citations

Modification of Experimental Aminoglycoside Nephrotoxicity

1986 • 31 citations

Penicillamine Induced Membranous Glomerulonephritis

1979 • 31 citations

Nephrotic Syndrome Secondary to Lithium Therapy

1982 • 29 citations

Comparison of cyclosporine nephrotoxicity with aminoglycoside nephrotoxicity.

1986 • 29 citations

Reversible Renal Failure due to the Use of Captopril in a Renal Allograft Recipient Treated with Cyclosporin

1989 • 28 citations

Cyclosporine--high-dose steroid interaction in renal transplant recipients: assessment by HPLC.

1987 • 27 citations

Renal artery occlusion in patients with renovascular hypertension treated with captopril.

1986 • 27 citations

Glomerular Sclerosis in Adults with Nephrotic Syndrome

1974 • 27 citations

Factors Influencing Survival in Acute Renal Failure

1989 • 26 citations

Chronic Amphotericin B Nephrotoxicity in the Rat, Protective Effect of Prophylactic Salt Loading

1988 • 26 citations

Acute nephrotic syndrome with reversible renal failure after phenylbutazone.

1981 • 26 citations

Immunopathology of penicillamine-induced glomerular disease.

1976 • 25 citations

INFLUENCE OF ERYTHROMYCIN ON CYCLOSPORINE PHARMACOKINETICS

1987 • 25 citations

Urinary indices in acute interstitial nephritis

1987 • 24 citations

Plasma Exchange in the Successful Treatment of Drug-Induced Renal Disease

1982 • 24 citations

Nephrotic syndrome associated with lithium therapy.

1981 • 23 citations

Membranous Glomerulonephritis as a Complication of Oral Gold Therapy

1982 • 22 citations

Toxicity of cyclosporine during treatment with androgens.

1985 • 21 citations

Gold nephropathy. An immunopathologic study.

1973 • 20 citations

Acute Renal Failure Associated With Ticrynafen

1980 • 19 citations

Ibuprofen-Associated Lipoid Nephrosis Without Interstitial Nephritis

1989 • 19 citations

Trimethadione (Tridione(R))-induced nephrotic syndrome

1973 • 19 citations

Nephrotic syndrome and renal failure associated with use of nonsteroidal anti-inflammatory drugs.

1980 • 18 citations

Metabolism and pharmacokinetics of penicillamine in rats -- an overview.

1981 • 18 citations

Uric acid nephrolithiasis and acute renal failure secondary to streptozotocin nephrotoxicity

1988 • 16 citations

The Pathology of Drug Nephrotoxicity

1983 • 16 citations

Acute renal failure and interstitial nephritis after clofibrate treatment.

1980 • 14 citations

Case 42-1983

1983 • 14 citations

A case of acute interstitial nephritis successfully treated after delayed diagnosis.

1979 • 13 citations

Chronic effects of oral sulindac on renal haemodynamics and hormones in subjects with chronic renal disease

1986 • 11 citations

ADVERSE EFFECTS OF ANGIOTENSIN-CONVERTING-ENZYME INHIBITORS

1990 • 10 citations

ADVERSE RENAL REACTIONS TO NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND POTASSIUM-SPARING DIURETICS

1988 • 10 citations

The nephrotic syndrome. II.

1953 • 10 citations

Nephrotoxicity of Common Drugs Used by Urologists

1990 • 10 citations

Nephrotoxicity of antifungal agents.

1985 • 9 citations

Fenclofenac induced interstitial nephritis confirmed by inadvertent rechallenge.

1985 • 9 citations

Prevention of delayed graft function in cadaveric kidney transplants by the calcium antagonist diltiazem and the prostacyclin-analogue iloprost--outcome of a prospective randomized clinical trial.

1989 • 9 citations

Effects of Dietary Electrolyte Supplementation on Gentamicin Nephrotoxicity

1988 • 8 citations

Generalized Lymphadenopathy and Nephrotic Syndrome as a Manifestation of Mephenytoin (Mesantoin) Toxicity

1976 • 7 citations

Nephrotic Syndrome Associated With Ethosuccimide

1978 • 7 citations

Early renal artery occlusion after enalapril in atheromatous renal artery stenosis.

1989 • 5 citations

[incidence of impaired kidney function in 2050 patients admitted to a general hospital; a prospective study].

1988 • 2 citations

Reducing the Incidence of Renal Failure in Australia: The Tale of Two Toxins

1990 • 1 citations

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