Function of renal γ-glutamyltransferase: Significance of glutathione and glutamine interactions

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Glutathione and Related γ-Glutamyl Compounds: Biosynthesis and Utilization

1976 • 846 citations

Principles of Renal Physiology

1956 • 679 citations

Metabolism of amino-acids

1935 • 559 citations

Interaction of γ-Glutamyl Transpeptidase with Amino Acids, Dipeptides, and Derivatives and Analogs of Glutathione

1974 • 541 citations

Isolation of γ-Glutamyl Transpeptidase from Hog Kidney

1965 • 459 citations

γ-Glutamyl-p-nitroanilide: A new convenient substrate for determination and study of l- and d-γ-glutamyltranspeptidase activities

1963 • 349 citations

γ‐Glutamyltransferase in kidney brush border membranes

1972 • 292 citations

Enzymic transpeptidation reactions involving γ-glutamyl peptides and α-amino-acyl peptides

1952 • 268 citations

Dynamic state of glutathione in blood plasma.

1980 • 249 citations

The fate of extracellular glutathione in the rat☆

1978 • 245 citations

AMINO ACID EXTRACTION AND AMMONIA METABOLISM BY THE HUMAN KIDNEY DURING THE PROLONGED ADMINISTRATION OF AMMONIUM CHLORIDE*

1963 • 237 citations

Isolated Brain Microvessels: A Purified, Metabolically Active Preparation from Bovine Cerebral Cortex

1974 • 226 citations

Identity of maleate-stimulated glutaminase with gamma-glutamyl transpeptidase in rat kidney.

1975 • 222 citations

Histochemical Demonstration of Gamma-Glutamyl Transpeptidase

1961 • 216 citations

HISTOCHEMICAL DEMONSTRATION OF A GAMMA-GLUTAMYL TRANSPEPTIDASE-LIKE ACTIVITY

1962 • 174 citations

Direct evidence for inter-organ transport of glutathione and that the non-filtration renal mechanism for glutathione utilization involves γ-glutamyl transpeptidase

1980 • 164 citations

Glutathionuria: Inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase

1975 • 148 citations

Regulation of Renal Ammoniagenesis

1974 • 143 citations

γ‐Glutamyl Transpeptidase: Sidedness of Its Active Site on Renal Brush‐Border Membrane

1978 • 136 citations

The Reaction of Glutathione with Amino Acids and Related Compounds as Catalyzed by γ-Glutamyl Transpeptidase

1959 • 133 citations

Characterization and Physiological Function of Rat Renal γ-Glutamyltranspeptidase

1979 • 131 citations

Comparison of the hydrolytic and transfer activities of rat renal gamma-glutamyltranspeptidase.

1979 • 127 citations

Principles of Renal Physiology

1994 • 120 citations

Ammonia production and glutamine incorporation into glutathione in the functioning rat kidney

1979 • 110 citations

PARTIAL PURIFICATION AND PROPERTIES OF RENAL GLUTAMINASE

1958 • 93 citations

The activities of the key enzymes of the γ‐glutamyl cycle in microdissected segments of the rat nephron

1977 • 78 citations

The Subcellular Localization of Glutaminase Isoenzymes in Rat Kidney Cortex

1974 • 78 citations

Glutaminase isozymes in rat kidney

1966 • 70 citations

Evidence that transpeptidation is a significant function of gamma-glutamyl transpeptidase.

1981 • 69 citations

Metabolism of Glutamine by the Intact Functioning Kidney of the Dog STUDIES IN METABOLIC ACIDOSIS AND ALKALOSIS

1972 • 62 citations

Tubular reabsorption of l-glutamine studied by free-flow micropuncture and microperfusion of rat kidney

1980 • 58 citations

Affinity labeling of γ‐glutamyl transpeptidase by glutamine antagonists

1980 • 55 citations

Modulation of the hydrolysis, transfer, and glutaminase activities of gamma-glutamyl transpeptidase by maleate bound at the cysteinylglycine binding site of the enzyme.

1979 • 54 citations

Subcellular localization of rat kidney phosphate independent glutaminase

1975 • 51 citations

Modulation of gamma-glutamyl transpeptidase activities by hippurate and related compounds.

1980 • 44 citations

Renal Hemodynamics and Ammoniagenesis

1974 • 37 citations

Ammonia production and pathways of glutamine metabolism in the isolated perfused rat kidney

1974 • 35 citations

METABOLISM OF GLUTATHIONE

1951 • 34 citations

Transport of the large-neutral amino acids by the γ-glutamyl cycle: A proposal

1977 • 32 citations

Influence of adrenal glands on pathways of renal glutamine utilization and ammonia production

1974 • 29 citations

Transport of glutamine by rat kidney brush-border membrane vesicles

1979 • 26 citations

Pyroglutamic aciduria: Rate of formation and degradation of pyroglutamate

1973 • 25 citations

Evidence for lumenal and antilumenal localization of γ-glutamyltranspeptidase in rat kidney

1981 • 22 citations

Differential effect of AT‐125 on rat renal glutaminase activities

1981 • 22 citations

Species differences in renal glutamine synthesis in vivo

1969 • 22 citations

Presence of γ-glutamyltransferase in the renal microvascular compartment

1981 • 21 citations

Separation of membrane-bound .gamma.-glutamyl transpeptidase from brush border transport and enzyme activities

1980 • 21 citations

Renal glutaminases: Diamox inhibition of glutamyltransferase

1975 • 20 citations

Localization of glutamine accumulation and tubular reabsorption in rat nephron

1978 • 19 citations

Acid-base behavior of the kidney in maleate-treated rats

1972 • 16 citations

Role of hippurate in acidosis induced adaptation in renal γ-glutamyltransferase

1981 • 15 citations

The effect of metabolic acidosis on γ‐glutamyltranspeptidase activity in the rat kidney

1977 • 15 citations

Renal glutamine utilization: glycylglycine stimulation of γ-glutamyltransferase

1980 • 13 citations

The effect of maleate on glutamine metabolism by rat kidney

1981 • 10 citations

Mechanism of the acidosis induced adaptation in renal γ-glutamyltransferase

1981 • 9 citations

THE INHIBITION BY ACETAZOLEAMIDE OF RENAL PHOSPHATE-ACTIVATED GLUTAMINASE IN RATS

1961 • 8 citations

Studies on two glutaminase systems from rat kidney

1968 • 5 citations

Die Abh�ngigkeit der Ammoniakproduktion von der GFR bei Ureterabklemmung und bei Durchblutungsdrosselung in der Hundeniere

1966 • 4 citations