cDCC (Chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction
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References (29)
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Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma.
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Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer
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Antisense RNA to the putative tumor-suppressor gene DCC transforms Rat-1 fibroblasts.
1992 • 88 citations
Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients.
1992 • 87 citations
Somatic genetic changes on chromosome 18 in breast carcinomas: is the DCC gene involved?
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Evidence for heterophilic adhesion of embryonic retinal cells and neuroblastoma cells to substratum-adsorbed NCAM
1992 • 43 citations
Persistent expression of the tumor suppressor gene DCC is essential for neuronal differentiation.
1992 • 42 citations
[38] Use of hydrophilicity plotting procedures to identify protein antigenic segments and other interaction sites
1989 • 36 citations
DCC: A Tumor Suppressor Gene Expressed on the Cell Surface
1992 • 31 citations