Calcineurin Inhibits Na+/Ca2+ Exchange in Phenylephrine-treated Hypertrophic Cardiomyocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

Ca ²⁺ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD

1999 • 1,136 citations

Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy

2001 • 696 citations

Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure.

1994 • 635 citations

Calcium Fluxes Involved in Control of Cardiac Myocyte Contraction

2000 • 562 citations

Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines.

1982 • 428 citations

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

2000 • 298 citations

Identification of the Syrian hamster cardiomyopathy gene

1997 • 274 citations

The Relationship Between Charge Movements Associated with I _Ca and I _Na-Ca in Cardiac Myocyte

1990 • 267 citations

A novel mechanism of myocyte degeneration involving the Ca2+-permeable growth factor–regulated channel

2003 • 261 citations

Calcineurin functions in Ca(2+)-activated cell death in mammalian cells.

1995 • 260 citations

Impaired cardiac hypertrophic response in Calcineurin Aβ -deficient mice

2002 • 240 citations

Cardiac Na ⁺ -Ca ²⁺ Exchange

2001 • 237 citations

Calcineurin Promotes Protein Kinase C and c-Jun NH2-terminal Kinase Activation in the Heart

2000 • 232 citations

Functional comparison of the three isoforms of the Na⁺/Ca²⁺ exchanger (NCX1, NCX2, NCX3)

1998 • 219 citations

Calx, a Na-Ca exchanger gene ofDrosophila melanogaster

1997 • 197 citations

PKCα regulates the hypertrophic growth of cardiomyocytes through extracellular signal–regulated kinase1/2 (ERK1/2)

2002 • 195 citations

Phosphorylation-dependent Regulation of Cardiac Na+/Ca2+ Exchanger via Protein Kinase C

1996 • 190 citations

Regulation of the plasma membrane Ca2+ pump by cyclic nucleotides in cultured vascular smooth muscle cells.

1988 • 188 citations

β-Adrenergic Pathway Induces Apoptosis through Calcineurin Activation in Cardiac Myocytes

2000 • 164 citations

Control of Cardiac Growth and Function by Calcineurin Signaling

2003 • 140 citations

Protein Kinase C-Dependent Regulation of Na⁺/Ca²⁺ Exchanger Isoforms NCX1 and NCX3 Does Not Require Their Direct Phosphorylation

1998 • 109 citations

Changes in Ca ²⁺ Cycling Proteins Underlie Cardiac Action Potential Prolongation in a Pressure-Overloaded Guinea Pig Model With Cardiac Hypertrophy and Failure

2000 • 89 citations

Na+-Ca2+ Exchanger Remodeling in Pressure Overload Cardiac Hypertrophy

2001 • 88 citations

Protein Kinase A Hyperphosphorylation Increases Basal Current but Decreases β-Adrenergic Responsiveness of the Sarcolemmal Na ⁺ -Ca ²⁺ Exchanger in Failing Pig Myocytes

2003 • 86 citations

Phenylephrine-induced stimulation of Na+/Ca2+ exchange in rat ventricular myocytes

1998 • 42 citations

DISSOCIATION OF FACTORS INFLUENCING MYOCARDIAL DEGENERATION AND GENERALIZED CARDIOCIRCULATORY FAILURE*

1969 • 36 citations

Physiological functions of the regulatory domains of the cardiac Na⁺/Ca²⁺exchanger NCX1

2000 • 35 citations

Mode-specific Inhibition of Sodium-Calcium Exchange during Protein Phosphatase Blockade

1999 • 19 citations