Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

1979 • 1,478 citations

Kainic acid as a tool in neurobiology

1978 • 1,314 citations

The Toxic Effect of Sodium L-Glutamate on the Inner Layers of the Retina

1957 • 1,061 citations

Iontophoretic studies of neurones in the mammalian cerebral cortex

1963 • 659 citations

A Ca²⁺ion-activated protease possibly involved in myofibrillar protein turnover. Purification from porcine muscle

1976 • 413 citations

Pharmacological characterization of different types of GABA and glutamate receptors in vertebrates and invertebrates☆☆☆

1979 • 392 citations

Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract

1978 • 330 citations

Agonist-induced myopathy at the neuromuscular junction is mediated by calcium.

1979 • 242 citations

Pharmacological Properties of Excitatory Neuromuscular Synapses in the Locust

1968 • 225 citations

The pharmacology and ionic dependency of amino acid responses in the frog spinal cord

1973 • 221 citations

Micromolar Calcium Stimulates Proteolysis and Glutamate Binding in Rat Brain Synaptic Membranes

1981 • 180 citations

Amino Acids as Neurotransmitters

1978 • 164 citations

Concanavalin A blocks desensitisation of glutamate receptors on insect muscle fibres

1976 • 157 citations

Metabolic Disorders of the Nervous System

1981 • 156 citations

Chemical and structural changes of neurofilaments in transected rat sciatic nerve

1978 • 144 citations

CORRELATED MORPHOLOGICAL AND PHYSIOLOGICAL STUDIES ON ISOLATED SINGLE MUSCLE FIBERS

1965 • 118 citations

Chemical Transmission at the Insect Excitatory Neuromuscular Synapse

1966 • 116 citations

Fine structure of normal and degenerating motor axons and nerve-muscle synapses in the locust,Schistocerca gregaria

1972 • 100 citations

A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Subcellular localization of the protease in porcine skeletal muscle.

1976 • 85 citations

Intrahippocampal injections of ibotenic acid provide histological evidence for a neurotoxic mechanism different from kainic acid

1979 • 79 citations

Glutamate Sensitivity of Denervated Insect Muscle Fibres

1969 • 77 citations

Voltage clamp studies of glutamate synapse

1974 • 74 citations

Non-random openings and concentration-dependent lifetimes of glutamate-gated channels in muscle membrane

1981 • 66 citations

Changes in Structural, Physiological and Pharmacological Properties of Insect Excitatory Nerve-muscle Synapses after Motor Nerve Section

1968 • 63 citations

Response of insect muscle to denervation—II. Changes in neuromuscular transmission

1963 • 60 citations

The entry of labelled calcium into the innervated region of the mouse diaphragm muscle

1974 • 59 citations

Desensitization of glutamate receptors on innervated and denervated locust muscle fibres.

1979 • 46 citations

Response of insect muscle to denervation—I. Resting potential changes

1963 • 46 citations

Ionic mechanisms associated with the depolarization by glutamate and aspartate on human and rat spinal neurones in tissue culture

1976 • 42 citations

Ultrastructural changes in muscle mitochondria in situ, including the apparent development of internal septa, associated with the uptake and release of calcium

1977 • 36 citations

Trans-synaptic regulation of tyrosine hydroxylase activity in adrenergic neurones: Effect of potassium concentration on cultured sympathetic ganglia

1972 • 34 citations

Effect of some “strong” excitants of central neurones on the uptake of L-glutamate and L-aspartate by synaptosomes

1974 • 32 citations

Action of kainic acid on a glutamatergic synapse

1975 • 31 citations

CORRELATED MORPHOLOGICAL AND PHYSIOLOGICAL STUDIES ON ISOLATED SINGLE MUSCLE FIBERS

1968 • 28 citations

Desensitization and potentiation during glutamate application to locust skeletal muscle

1978 • 26 citations

Role of excitatory pathways in the hippocampal damage produced by kainic acid.

1981 • 24 citations

RESPONSES TO <scp>dl</scp>‐IBOTENIC ACID AT LOCUST GLUTAMATERGIC NEUROMUSCULAR JUNCTIONS

1979 • 20 citations

Permeability of insect muscle fibres to potassium and chloride ions.

1967 • 20 citations

Denervation of insect muscle: A comparative study of the changes in L-Glutamate sensitivity on locust retractor unguis and extensor tibiae muscle

1979 • 17 citations

Relative ‘trophic’ influences of excitatory and inhibitory innervation of locust skeletal muscle fibres

1979 • 13 citations