Pharmacophore identification of a chemokine receptor (CXCR4) antagonist, T22 ([Tyr 5,12 , Lys 7 ]-polyphemusin II), which specifically blocks T cell-line-tropic HIV-1 infection

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

1988 • 1,634 citations

Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.

1988 • 526 citations

A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection

1997 • 391 citations

Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions

1990 • 319 citations

Acetamidomethyl. A Novel Thiol Protecting Group for Cysteine

1972 • 309 citations

Purification and characterization of an avian myeloblastosis and human immunodeficiency virus reverse transcriptase inhibitor, sulfated polysaccharides extracted from sea algae

1987 • 188 citations

Anti-human immunodeficiency virus activity of a novel synthetic peptide, T22 ([Tyr-5,12, Lys-7]polyphemusin II): a possible inhibitor of virus-cell fusion

1992 • 150 citations

A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II)

1992 • 125 citations

A comparative study of the solution structures of tachyplesin I and a novel anti-HIV synthetic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), determined by nuclear magnetic resonance

1993 • 102 citations

Studies on peptides. CLV. Evaluation of trimethylsilyl bromide as a hard-acid deprotecting reagent in peptide synthesis.

1987 • 95 citations

Inhibitory Effect of Tachyplesin I on the Proliferation of Human Immunodeficiency Virus in vitro

1991 • 73 citations

A New Method for the Protection of the Sulfhydryl Group during Peptide Synthesis

1964 • 63 citations

Silver trifluoromethanesulphonate as an S-deprotecting reagent for the synthesis of cystine peptides

1989 • 58 citations

Antimicrobial Activity and Conformation of Tachyplesin I and Its Analogs.

1993 • 56 citations

Structure-Activity Relationships of an Anti-HIV Peptide, T22

1994 • 45 citations

Analysis of the interaction of an anti-HIV peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), with gp 120 and CD4 by surface plasmon resonance

1996 • 33 citations

Downsizing of an HIV–cell fusion inhibitor, T22 ([Tyr 5, 12 , Lys 7 ]-Polyphemusin II), with the maintenance of anti-HIV activity and solution structure 1

1998 • 30 citations

Disulfide bond‐forming reaction using a dimethyl sulfoxide/aqueous HCl system and its application to regioselective two disulfide bond formation

1995 • 29 citations

Combination of a new amide-precursor reagent and trimethylsilyl bromide deprotection for the Fmoc-based solid phase synthesis of human pancreastatin and one of its fragments (Fmoc = fluoren-9-ylmethoxycarbonyl)

1988 • 18 citations

The Synthetic (Tyr5,12,Lys7)-Polyphemusin II Peptide (T22) Binds to the CD4 Cell Surface Molecule

1995 • 14 citations

Solution-Phase Synthesis of an Anti-human Immunodeficiency Virus Peptide, T22 ((Tyr5,12, Lys7)-Polyphemusin II), and the Modification of Trp by the p-Methoxybenzyl Group of Cys during Trimethylsilyl Trifluoromethanesulfonate Deprotection.

1995 • 13 citations

Molecular Size of an Anti-HIV Peptide, T22, Can Be Reduced without Loss of the Activity

1996 • 7 citations