Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae

1983 • 810 citations

Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence data

1975 • 638 citations

Evolution of enzyme function and the development of catalytic efficiency

1976 • 604 citations

Stereochemical basis of heat stability in bacterial ferredoxins and in haemoglobin A2

1975 • 420 citations

Microdissection and cloning of DNA from a specific region of Drosophila melanogaster polytene chromosomes

1981 • 341 citations

The Conformation of Thermolysin

1974 • 332 citations

A precursor of globin messenger RNA

1976 • 254 citations

The Mechanism of the Triosephosphate Isomerase Reaction

1959 • 218 citations

On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase

1981 • 216 citations

Molecular basis of thermostability in the lysozyme from bacteriophage T4

1979 • 212 citations

Thermodynamic stability and point mutations of bacteriophage T4 lysozyme

1984 • 149 citations

Human triosephosphate isomerase cDNA and protein structure. Studies of triosephosphate isomerase deficiency in man.

1985 • 121 citations

Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family.

1985 • 99 citations

Active site of triosephosphate isomerase: in vitro mutagenesis and characterization of an altered enzyme.

1985 • 98 citations

Nucleotide sequence of the triose phosphate isomerase gene of Saccharomyces cerevisiae.

1982 • 95 citations

Triose phosphate isomerase from the coelacanth. An approach to the rapid determination of an amino acid sequence with small amounts of material

1974 • 87 citations

Chicken triosephosphate isomerase complements an Escherichia coli deficiency.

1985 • 76 citations

The amino acid sequence of rabbit muscle triose phosphate isomerase

1975 • 69 citations

Primary structure of human triosephosphate isomerase.

1984 • 63 citations

Frequency of enzyme deficiency variants in erythrocytes of newborn infants.

1981 • 63 citations

Nucleotide sequence of the triose phosphate isomerase gene of Escherichia coli

1984 • 57 citations

Genetic and non‐genetic variation of triose phosphate isomerase isozymes in human tissues

1973 • 51 citations

The frequency among Japanese of heterozygotes for deficiency variants of 11 enzymes.

1983 • 50 citations

Elevated Frequency of Carriers for Triosephosphate Isomerase Deficiency in Newborn Infants

1982 • 48 citations

Primary Structure of Triosephosphate Isomerase from Bacillus stearothermophilus

1980 • 46 citations

Studies on the subunit structure and amino acid sequence of triose phosphate isomerase from chicken breast muscle

1974 • 46 citations

Characteristics of enzymes of erythrocytes from newborn infants and adults: Activity, thermostability, and electrophoretic profile as a function of cell age

1981 • 40 citations

Triosephosphate isomerase deficiency with hemolytic anemia and severe neuromuscular disease. Familial and biochemical studies of a case found in Spain

1978 • 38 citations

An analysis of the structure of triose phosphate isomerase and its comparison with lactate dehydrogenase

1978 • 38 citations

Hereditary deficiency of triosephosphate isomerase in four unrelated families

1979 • 37 citations

Changes in the activity and isozyme patterns of glycolytic enzymes during stimulation of normal human lymphocytes with phytohaemagglutinin

1980 • 31 citations

Crystallization of yeast triose phosphate isomerase from polyethylene glycol. Protein crystal formation following phase separation.

1981 • 28 citations

Characterization of the Functional Gene and Several Processed Pseudogenes in the Human Triosephosphate Isomerase Gene Family

1985 • 24 citations

Origin of the triosephosphate isomerase isozymes in humans: genetic evidence for the expression of a single structural locus.

1981 • 24 citations

Probing the catalytic mechanism of yeast triose phosphate isomerase by site-specific mutagenesis

1984 • 24 citations

The Structure and Stability of Thermolysin

1976 • 23 citations

The synthesis of a labile triosephosphate isomerase isozyme in human lymphoblasts and fibroblasts

1977 • 19 citations

Cell proliferation-associated expression of a recently evolved isozyme of triosephosphate isomerase

1985 • 12 citations

Regional mapping of <i>TPI, LDH-B,</i>and <i>Pep-B</i> on chromosome 12 of man

1975 • 11 citations