Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Thickness, Cross-Sectional Areas and Depth of Invasion in the Prognosis of Cutaneous Melanoma

1970 • 2,415 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas.

1989 • 511 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.

1988 • 432 citations

In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

1988 • 374 citations

Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas. Activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor.

1988 • 324 citations

SPONTANEOUS REGRESSION OF CANCER

1964 • 322 citations

Spontaneous regression of primary malignant melanomas with regional metastases

1965 • 304 citations

An experimentally validated panel of subfamily‐specific oligonucleotide primers (V_α1‐w29/V_β1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

1992 • 302 citations

Immunochemical Proof That a Novel Rearranging Gene Encodes the T Cell Receptor δ Subunit

1987 • 278 citations

Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens.

1989 • 223 citations

The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens.

1989 • 215 citations

Spontaneous regression of melanoma

1975 • 214 citations

Production of stable cytolytic T‐cell clones directed against autologous human melanoma

1987 • 209 citations

Thin Malignant Melanomas With Regression and Metastases

1987 • 190 citations

Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.

1989 • 188 citations

Predominant Expression of T Cell Receptor V _α 7 in Tumor-Infiltrating Lymphocytes of Uveal Melanoma

1990 • 169 citations

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

1988 • 148 citations

Prognosis in patients with thin malignant melanoma: influence of regression

1983 • 144 citations

Clonal analysis of cytotoxic and regulatory T cell responses against human melanoma.

1989 • 130 citations

Spontaneous regression of malignant melanoma: a review of the literature on incidence, clinical features, and possible mechanisms.

1976 • 120 citations

Human tumor infiltrating lymphocytes. Analysis of lymphokine mRNA expression and relevance to cancer immunotherapy.

1989 • 111 citations

Clonal analysis of cytotoxic T‐lymphocyte response to autologous human metastatic melanoma

1985 • 107 citations

Structural Properties and Tissue Distribution of the Antigen Recognized by the Monoclonal Antibody 653.40S to Human Melanoma Cells<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 97 citations

In situ analysis of the mononuclear cell infiltrate in primary malignant melanoma of the skin.

1983 • 93 citations

Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response.

1990 • 75 citations

Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer

1991 • 59 citations

Selective expansion of a specific anti‐tumor CD8⁺ cytotoxic T lymphocyte clone in the bulk culture of tumor‐infiltrating lymphocytes from a melanoma patient: Cytotoxic activity and T cell receptor gene rearrangements

1990 • 58 citations

Analysis of T-cell receptor alpha/beta variability in lymphocytes infiltrating a melanoma metastasis.

1992 • 52 citations

[Histology and prognosis in cutaneous malignant melanoma].

1977 • 46 citations

Oligoclonal T lymphocytes infiltrating human lung cancer tissues

1991 • 31 citations

Depletion of T-cells with the CD4+CD45R+ phenotype in lymphocytes that infiltrate subcutaneous metastases of human melanoma.

1989 • 30 citations

Post-transcriptional allelic exclusion of two functionally rearranged T cell receptor α genes

1989 • 29 citations

Thin malignant melanomas with regression and metastases

1987 • 28 citations

Multiple epitope recognition: An approach to improved radioimmunodetection of tumor‐associated antigens

1987 • 25 citations

Human tumor-infiltrating lymphocytes

1993 • 19 citations

Oligoclonal expansion of Vβ8+ cells in interleukin-2-activated T cells residing in subcutaneous metastatic melanoma

1992 • 12 citations

Spontaneous Regression of Malignant Melanoma

1978 • 11 citations

Oligoclonal T lymphocytes infiltrating human lung cancer tissues

1991 • 2 citations