Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Histology for Pathologists

1992 • 820 citations

Evolution of the nuclear receptor gene superfamily.

1992 • 662 citations

Spatial and temporal expression of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system

1992 • 536 citations

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1

1998 • 503 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function.

1996 • 432 citations

The T3Ralpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production

1997 • 341 citations

Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptor genes.

1990 • 308 citations

Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats.

1990 • 298 citations

Differential expression of alpha and beta thyroid hormone receptor genes in rat brain and pituitary.

1989 • 251 citations

Gene expression during metamorphosis: An ideal model for post‐embryonic development

1993 • 243 citations

Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene

1997 • 210 citations

Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes

1989 • 203 citations

Thyroid Hormone Action on Liver, Heart, and Energy Expenditure in Thyroid Hormone Receptor β-Deficient Mice**Presented in part at the 69th Annual Meeting of the American Thyroid Association Meeting, November 14–17, 1996, San Diego, California. This study was supported in part by the National Institutes of Health Grant DK-17050 and the Seymour J. Abrams Thyroid Research Center; a grant from the Ministry of Health and Welfare, Japan (to H.S.); and Grant-in-Aid for Scientific Research (09671044) …

1998 • 169 citations

Identification of Transcripts Initiated from an Internal Promoter in the c-erbAα Locus That Encode Inhibitors of Retinoic Acid Receptor-α and Triiodothyronine Receptor Activities

1997 • 167 citations

The expression of thyroid hormone receptors in human bone

1997 • 149 citations

Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes.

1991 • 149 citations

Human carboxyl-terminal variant of alpha-type c-erbA inhibits trans-activation by thyroid hormone receptors without binding thyroid hormone.

1989 • 129 citations

Thyroid Hormone Inhibition of Human Thyrotropin β-Subunit Gene Expression is Mediated by a Cis-acting Element Located in the First Exon

1989 • 119 citations

Thyrotropin Regulation by Thyroid Hormone in Thyroid Hormone Receptor β-Deficient Mice¹

1997 • 102 citations

Immunofluorescence localization of thyroid hormone receptor protein beta 1 and variant alpha 2 in selected tissues: cerebellar Purkinje cells as a model for beta 1 receptor-mediated developmental effects of thyroid hormone in brain.

1991 • 98 citations

Assignment of the beta-thyroid hormone receptor to 3,5,3'-triiodothyronine-dependent inhibition of transcription from the thyrotropin-releasing hormone promoter in chick hypothalamic neurons.

1992 • 87 citations

Characterization of Site-Specific Polyclonal Antibodies to c-erbA Peptides Recognizing Human Thyroid Hormone Receptors α1, α2, and β and native 3,5,3′- Triiodothyronine Receptor, and Study of Tissue Distribution of the Antigen

1990 • 74 citations

Involvement of Thyroid Hormone and Its α Receptor in Avian Neurulation

1998 • 69 citations

Endocrinology of Amphibian Metamorphosis

1996 • 59 citations

Ligand T3 Dependent and Independent Effects of Thyroid Hormone Receptors upon Human TRH Gene Transcription in Neuroblastoma Cells

1994 • 35 citations

Metabolic alterations induced by chronic heat exposure in the rat: the involvement of thyroid function

1984 • 32 citations

Bone and Mineral Research, Annual 1: A Yearly Survey of Developments in the Field of Bone and Mineral Metabolism

1983 • 17 citations

Differential Regulation of the Human Thyrotropin α-Subunit Promoter by Thyroid Hormone Receptors α1 and β1

1998 • 9 citations

Analysis of the functional state of T3 nuclear receptors expressed in thyroid cells

1996 • 8 citations

Deleted Work

1955 • 0 citations