Insulin-like growth factor-1 and growth hormone (GH) have distinct and overlapping anabolic effects in GH-deficient rats

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. 1956.

1990 • 1,075 citations

Treatment of adults with growth hormone (GH) deficiency with recombinant human GH.

1993 • 845 citations

Insulin-like growth factor I stimulates growth in hypophysectomized rats

1982 • 605 citations

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

1988 • 424 citations

Insulin-Like Growth Factors: A Role in Growth Hormone Negative Feedback and Body Weight Regulation via Brain

1983 • 354 citations

Endocrinology and Metabolism

1996 • 353 citations

Enhancement of the anabolic effects of growth hormone and insulin-like growth factor I by use of both agents simultaneously.

1993 • 336 citations

Growth hormone-deficient dwarfism in the rat: a new mutation

1988 • 239 citations

Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats

1986 • 136 citations

Growth Responses in a Mutant Dwarf Rat to Human Growth Hormone and Recombinant Human Insulin-Like Growth Factor I

1989 • 123 citations

Recombinant human insulin-like growth factor: testing the somatomedin hypothesis in hypophysectomized rats

1987 • 115 citations

Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans.

1992 • 85 citations

Stimulation of Supranormal Growth in Prepubertal, Adult Plateaued, and Hypophysectomized Female Rats by Large Doses of Rat Growth Hormone: Physiological Effects and Adverse Consequences*

1987 • 84 citations

Discordance of Serum and Tissue Somatomedin Levels in Growth Hormone-Stimulated Growth in the Rat*

1988 • 62 citations

Differential actions of growth hormone and insulin-like growth factor-I on tissue protein metabolism in dwarf mice.

1992 • 56 citations

Effects of rhGH and rhIGF-1 on renal growth and morphology

1993 • 47 citations

Equivalent Potency and Pharmacokinetics of Recombinant Human Growth Hormones with or without an N-Terminal Methionine

1988 • 28 citations

The Effect of the Frequency of Subcutaneous Insulin-Like Growth Factor-1 Administration on Weight Gain in Growth Hormone Deficient Mice

1991 • 20 citations