Peritoneal exudate lymphocyte and mixed lymphocyte culture hybridomas are cytolytic in the absence of cytotoxic cell proteinases and perforin

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1987 • 196 citations

Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes

1987 • 174 citations

Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells

1991 • 166 citations

Purified perforin induces target cell lysis but not DNA fragmentation.

1989 • 162 citations

Cell specificity of granzyme gene expression.

1990 • 136 citations

Killing of target cells by lymphocytes: a mechanistic view.

1989 • 134 citations

Highly lytic in vivo primed cytolytic T lymphocytes devoid of lytic granules and BLT-esterase activity acquire these constituents in the presence of T cell growth factors upon blast transformation in vitro.

1988 • 79 citations

Lymphocyte-triggered internal target disintegration

1991 • 75 citations

High activity of N-alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine esterase and cytolytic perforin in cloned cell lines is not demonstrable in in-vivo-induced cytotoxic effector cells.

1987 • 72 citations

Cytotoxic T lymphocyte hybridomas that mediate specific tumor-cell lysis in vitro.

1981 • 72 citations

T-lymphocyte-mediated cytolysis as an excitatory process of the target

1985 • 71 citations

CTLA-1 and CTLA-3 serine esterase transcripts are detected mostly in cytotoxic T cells, but not only and not always.

1987 • 59 citations

In vivo primed mouse T cells selectively express T cell-specific serine proteinase-1 and the proteinase-like molecules granzyme B and C

1991 • 44 citations

Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes.

1989 • 43 citations

Lymphocyte‐Mediated Cytolysis

1988 • 37 citations

Monoclonal cytotoxic T lymphocyte hybridomas capable of specific killing activity, antigenic responsiveness, and inducible interleukin secretion.

1983 • 33 citations