On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem

1986 • 4,155 citations

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

1983 • 1,247 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS

1981 • 728 citations

Assay of tyrosine hydroxylase by coupled decarboxylation of dopa formed from 1-14C-l-tyrosine

1971 • 461 citations

Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract

1978 • 330 citations

BINDING OF [³H]KAINIC ACID, AN ANALOGUE OF <scp>l</scp>‐GLUTAMATE, TO BRAIN MEMBRANES

1976 • 308 citations

Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors

1982 • 285 citations

Actions of several anthelmintics and insecticides on rat cortical neurones

1970 • 266 citations

Comparison of ibotenate and kainate neurotoxicity in rat brain: A histological study

1983 • 236 citations

Glutamic acid and excitatory nerve endings: reduction of glutamic acid uptake after axotomy

1977 • 215 citations

Central actions of ibotenic acid and muscimol

1968 • 208 citations

HIGH AFFINITY <scp>l</scp>‐[³H]GLUTAMATE BINDING TO POSTSYNAPTIC RECEPTOR SITES ON RAT CEREBELLAR MEMBRANES

1978 • 199 citations

Excitatory amino acid analogues: Neurotoxicity and seizures

1982 • 188 citations

Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues

1978 • 182 citations

Glutamate neurotoxicity and Huntington's chorea

1978 • 173 citations

Comparative toxicity of kainic acid and other acidic amino acids toward rat hippocampal neurons

1981 • 160 citations

STANDARDIZATION OF A RADIOCHEMICAL ASSAY OF CHOLINE ACETYLTRANSFERASE AND A STUDY OF THE ACTIVATION OF THE ENZYME IN RABBIT BRAIN

1971 • 149 citations

Chloride and calcium ions reveal a pharmacologically distinct population of L-glutamate binding sites in synaptic membranes: correspondence between biochemical and electrophysiological data

1982 • 126 citations

Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus

1983 • 110 citations

Distinct pharmacological properties of excitatory amino acid receptors in the rat striatum: study by Na+ efflux assay.

1981 • 91 citations

Glutamate-preferring receptors regulate the release of D-[3H]aspartate from rat hippocampal slices

1981 • 86 citations

Antagonism of Excitatory Amino Acid-Induced and Synaptic Excitation of Spinal Neurones by cis-2,3-Piperidine Dicarboxylate

1981 • 83 citations

Chloride ions enhance L-glutamate binding to rat brain synaptic membranes

1982 • 82 citations

Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants

1982 • 60 citations

Hippocampal lesions indicate differences between the excitotoxic properties of acidic amino acids

1979 • 56 citations

3H-kainic acid binding: Relevance for evaluating the neurotoxicity of kainic acid

1979 • 51 citations

α-Amino-ω-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus

1982 • 45 citations

Is there a selectivity of neuronal degeneration induced by intrastriatal injection of kainic acid?

1979 • 39 citations

THE EFFECTS OF CYCLIC DICARBOXYLIC ACIDS ON SPONTANEOUS AND AMINO ACID‐EVOKED ACTIVITY OF RAT CORTICAL NEURONES

1982 • 36 citations

2-Amino-7-phosphonoheptanoic acid as an amino acid antagonist

1982 • 15 citations

The Neurodegenerative Properties Of Intracerebral Quinolinic Acid And Its Structural Analog Cis-2,3-Piperidine Dicarboxylic Acid

1983 • 11 citations