Azathioprine, a clastogen in human somatic cells? Analysis of chromosome damage and SCE in lymphocytes after exposure in vivo and in vitro

New Giemsa method for the differential staining of sister chromatids

1974 • 3,198 citations

Immunosuppression during pregnancy: Transmission of azathioprine and its metabolites from the mother to the fetus

1973 • 195 citations

Chromosome Studies in Patients Treated With Azathioprine and Amethopterin

1967 • 133 citations

Long‐term maintenance therapy with azathioprine in systemic lupus erythematosus

1975 • 103 citations

IMMUNOSUPPRESSIVE DRUGS AND THE FOETUS

1976 • 89 citations

Leukocyte Mitosis: Suppression in vitro Associated with Acute Infectious Hepatitis

1967 • 88 citations

Lymphocyte chromosome studies in humans exposed to chemical mutagens

1976 • 85 citations

Chromosome Aberrations in the Child of a Kidney Transplant Recipient

1971 • 77 citations

Effect of azathioprine on the chromosome complement of human bone marrow cells

1970 • 69 citations

Mechanisms of Action of Drugs Affecting Immune Responses

1972 • 67 citations

FERTILITY AFTER RENAL TRANSPLANTATION

1970 • 63 citations

The metabolic fate of the methylnitroimidazole moiety of azathioprine in the rat.

1973 • 57 citations

The 11th Report of the Human Renal Transplant Registry

1973 • 56 citations

Pregnancy following kidney homotransplantation from a non-twin. Report of a case with concurrent administration of azathioprine and prednisone.

1967 • 52 citations

Pregnancy following cadaver kidney homotransplantation

1970 • 51 citations

In vivo cytogenetic screening methods for mutagens, with special reference to the micronucleus test

1979 • 50 citations

CHROMOSOMAL BREAKS IN HUMAN LEUCOCYTE CULTURES INDUCED BY AN AGENT IN THE PLASMA OF INFECTIOUS HEPATITIS PATIENTS1

2009 • 49 citations

Successful, Normal Childbirth After Kidney Homotransplantation

1967 • 46 citations

Problems from immunosuppressives during pregnancy

1971 • 40 citations

Mutagenicity testing of 3 hallucinogens: LSD, psilocybin and‡ 9-THC using the micronucleus test

1978 • 39 citations

Chromosomes in patients treated with Imuran

1968 • 34 citations

Cancer and Teratogenesis: Infrequent Occurrence after Medical Use of Immunosuppressive Drugs*

1977 • 33 citations

Birth Defects in Child of Male Recipient of Kidney Transplant

1970 • 32 citations

Pregnancy and azathioprine in systemic lupus erythematosus

1974 • 32 citations

Chromosome Aberrations in Human Cells Following Treatment with Imuran

1966 • 31 citations

Investigation into the mutagenic activity of azathioprine (Imuran®) in different test systems

1979 • 29 citations

A FINE FOREHAND

1974 • 27 citations

Assessment of the effect of azathioprine on human bone marrow cells in vivo, combining chromosome studies and the micronucleus test.

1976 • 25 citations

Pregnancy following kidney homotransplantation from a non-twin

1967 • 24 citations

Cytogenetic analysis of human chromosomes and its valu for the estimation of genetic risk

1976 • 23 citations

Chromosome studies in 14 patients with disseminated sclerosis

1971 • 21 citations

Chromosomenabnormit�ten und Behandlung mit Imuran� (Azathioprin) nach Nierentransplantationen

1970 • 20 citations

Chromosomes in patients treated with Azathioprine

1973 • 19 citations

MEDICINE AND RELIGION A NEW JOURNAL DEPARTMENT

1967 • 18 citations

CHROMOSOMES IN INFECTIOUS HEPATITIS

1966 • 16 citations

Comparison of micronucleus test and chromosome examination in detecting potential chromosome mutagens

1977 • 13 citations

Chromosomal damage associated with infectious hepatitis and its possible teratogenic significance

1968 • 12 citations

Mutagenic effects of different mutagens on human chromosomes in vitro and in vivo as detected by conventional and “harlequin” methods

1978 • 10 citations

The clastogenic effect of azathioprine on human chromosomes in vitro

1974 • 9 citations

[Chromosome mutation caused by azathioprine in human leukocytes in vitro].

1971 • 8 citations

Some Chromosomal Studies on Patients with Infectious Hepatitis

1966 • 7 citations

Chromosomenuntersuchungen bei Kindern von Imuran�-behandelten Eltern

1971 • 7 citations

[Cytostatic immunosuppressive therapy, chromosomal aberrations and carcinogenic effect (author's transl)].

1974 • 6 citations

[Chromosome study in 14 psoriatic patients treated with hydroxyurea and azathioprine].

1973 • 6 citations

Chromosomenuntersuchungen an peripheren Lymphozyten bei Patienten mit multipler Sklerose^*

1975 • 5 citations

Mitoseaktivit�t und Chromosomenanalyse in peripheren Lymphocyten ALG-behandelter Patienten

1970 • 4 citations

A chromosome study in multiple sclerosis

1973 • 3 citations

[Pregnancy following renal transplantation].

1974 • 2 citations

Über die Pharmakokinetik des Azathioprins im Tierversuch und bei Patienten mit chronischen Lebererkrankungen

1973 • 2 citations

Effect of some hemiotherapeutics on frequency of lymphocytes chromosomal aberrations in certain systemic diseases

1978 • 1 citations