On the Reaction Kinetics of the Radioadaptive Response in Cultured Mouse Cells

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

A simple technique for demonstrating centromeric heterochromatin

1972 • 4,206 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

The catalytic decomposition of hydrogen peroxide by iron salts

1934 • 2,483 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1989 • 1,126 citations

Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

1973 • 843 citations

Adaptive Response of Human Lymphocytes to Low Concentrations of Radioactive Thymidine

1984 • 817 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Ras -Transformed Cells: Altered Levels of Phosphatidylinositol-4,5-Bisphosphate and Catabolites

1986 • 450 citations

Elevated levels of diacylglycerol and decreased phorbol ester sensitivity in ras-transformed fibroblasts

1987 • 330 citations

Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.

1984 • 283 citations

Human Lymphocytes Exposed to Low Doses of Ionizing Radiations Become Refractory to High Doses of Radiation as Well as to Chemical Mutagens that Induce Double-strand Breaks in DNA

1988 • 283 citations

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

1991 • 277 citations

Characterization of the Adaptive Response to Ionizing Radiation Induced by Low Doses of X Rays to Human Lymphocytes

1987 • 273 citations

Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiation

1987 • 235 citations

Evidence that the [³H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism

1986 • 224 citations

Radiation-Induced Adaptive Response for Protection against Micronucleus Formation and Neoplastic Transformation in C3H 10T1/2 Mouse Embryo Cells

1994 • 216 citations

Induction of the Adaptive Response by X-rays is Dependent on Radiation Intensity

1989 • 180 citations

Variability of the adaptive response to ionizing radiations in humans

1989 • 169 citations

Low dose radiation : biological bases of risk assessment

1989 • 162 citations

Biological Consequences of Gene Regulation After Ionizing Radiation Exposure

1991 • 160 citations

Adaptive response of human lymphocytes to low-level radiation from radioisotopes or X-rays

1989 • 153 citations

Is Radiation All Bad? The Search for Adaptation

1992 • 142 citations

Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.

1991 • 138 citations

Chromosomal responses to ionizing radiation reminiscent of and adaptive response in cultured Chinese hamster cells

1987 • 128 citations

Regulation of protein kinase C by ionizing radiation.

1990 • 128 citations

Cell Growth and Differentiation

2004 • 124 citations

Inhibition of the adaptive response of human lymphocytes to very low doses of ionizing radiation by the protein synthesis inhibitor cycloheximide

1989 • 124 citations

Exposure of human lymphocytes to ionizing radiation reduces mutagenesis by subsequent ionizing radiation

1986 • 118 citations

Chromosomal Aberrations: Basic and Applied Aspects

2011 • 118 citations

Enhancement of X-ray transformation by 12-O-tetradecanoyl-phorbol-13-acetate in a cloned line of C3H mouse embryo cells.

1978 • 111 citations

Human lymphocytes exposed to low doses of X-rays are less susceptible to radiation-induced mutagenesis

1991 • 107 citations

Radio-adaptive response: characterization of a cytogenetic repair induced by low-level ionizing radiation in cultured Chinese hamster cells

1989 • 104 citations

Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways.

1988 • 99 citations

Adaptive response to chromosome damage in cultured human lymphocytes primed with low doses of X-rays

1991 • 96 citations

Chromosomal Adaptive Response in Human Lymphocytes

1994 • 86 citations

Cytogenetic and survival adaptive responses in G1 phase human lymphocytes

1992 • 81 citations

Decreased Deletion Mutation in Radioadapted Human Lymphoblasts

1993 • 80 citations

Adaptive response of human lymphocytes for the repair of radon-induced chromosomal damage

1991 • 73 citations

Vanadate-Mediated Hydroxyl Radical Generation from Superoxide Radical in the Presence of NADH: Haber-Weiss vs Fenton Mechanism

1993 • 62 citations

Possible Causes of Variability of the Adaptive Response in Human Lymphocytes

1990 • 55 citations

Absence of adaptive response to low-level irradiation from tritiated thymidine and X-rays in lymphocytes of two individuals examined in serial experiments

1989 • 52 citations

Adaptive response to radiation damage in human lymphocytes conditioned with hydrogen peroxide as measured by the cytokinesis-block micronucleus technique

1993 • 49 citations

Lack of adaptive response to low doses of ionizing radiation in human lymphocytes from five different donors

1992 • 47 citations

Establishment and some mutational characteristics of 3T3‐like near‐diploid mouse cell line

1987 • 40 citations

Absence of Adaptive Response to Low Doses of X-rays in Preimplantation Embryos and Spleen Lymphocytes of an Inbred Mouse Strain as Compared to Human Peripheral Lymphocytes: A Cytogenetic Study

1992 • 39 citations

Evidence for Induced Radioresistance from Survival and Other End Points: An Introduction

1994 • 35 citations

Adaptive response after X-irradiation of human lymphocytes?

1989 • 34 citations

Adaptive response in irradiated human lymphocytes: radiobiological and genetical aspects

1991 • 32 citations

A BrdU pulse double-labelling method for studying adaptive response

1991 • 28 citations

Construction of Mouse A9 Clones Containing a Single Human Chromosome (X/Autosome Translocation) via Micro‐cell Fusion

1989 • 26 citations

Adaptive response in human lymphocytes conditioned with hydrogen peroxide before irradiation with X-rays

1990 • 26 citations

Multiple signal transduction pathways mediate c-Jun protein phosphorylation.

1993 • 25 citations

Ionizing Radiation Damage to DNA

1999 • 22 citations

Cultured mouse SR-1 cells exposed to low dose of γ-rays become less susceptible to the induction of mutagenesis by radiation as well as bleomycin

1993 • 22 citations

On the Genetic Background of the Adaptive Response to X-rays inDrosophila Melanogaster

1994 • 19 citations

The involvement of chromosome 13 in the X-ray-induced in vitro transformation of mouse m5S cells.

1987 • 19 citations

Evidence that the adaptive response of human lymphocytes to ionizing radiation acts on lethal damage in nonaberrant cells

1993 • 19 citations

Abolishment of c‐fos Inducibility in ras‐Transformed Mouse Osteoblast Cell Lines

1989 • 16 citations

Sister-chromatid exchanges induced by mitomycin C after exposure of human lymphocytes in G0 to a low dose of X-radiation

1987 • 15 citations

Effect of cycloheximide on the adaptive response induced by low dose radiation.

1992 • 14 citations