Deoxycorticosterone Acetate Plus Salt Induces Overexpression of Vascular Endothelin-1 and Severe Vascular Hypertrophy in Spontaneously Hypertensive Rats

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Physiological aspects of primary hypertension.

1982 • 1,787 citations

Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1

1994 • 1,002 citations

Small artery structure in hypertension. Dual processes of remodeling and growth.

1993 • 645 citations

Endothelin is a potent mitogen for rat vascular smooth muscle cells

1989 • 509 citations

Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells

1989 • 496 citations

Remodeling of cerebral arterioles in chronic hypertension.

1989 • 493 citations

Transforming growth factor-β stimulates the expression of endothelin mRNA by vascular endothelial cells

1989 • 420 citations

Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.

1992 • 358 citations

Growth factor activity of endothelin on vascular smooth muscle

1990 • 325 citations

Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy.

1994 • 286 citations

Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats.

1993 • 278 citations

cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA

1991 • 226 citations

Growth factor expression in aorta of normotensive and hypertensive rats.

1989 • 195 citations

Plasma Endothelin in Human Essential Hypertension

1991 • 195 citations

Thrombin enhances the release of endothelin from cultured porcine aortic endothelial cells

1989 • 185 citations

Histology of subcutaneous small arteries from patients with essential hypertension.

1993 • 171 citations

Increased expression of endothelin-1 gene in blood vessels of deoxycorticosterone acetate-salt hypertensive rats.

1993 • 163 citations

Mechanics and composition of cerebral arterioles in renal and spontaneously hypertensive rats.

1993 • 146 citations

The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes

1983 • 145 citations

Molecular and cellular biology of endothelin and its receptors

1996 • 110 citations

Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients

1992 • 109 citations

Plasma concentrations of endothelin-1 in spontaneously hypertensive rats and DOCA-salt hypertensive rats

1990 • 107 citations

Mechanics of large and small cerebral arteries in chronic hypertension

1994 • 92 citations

Endothelin stimulates protein synthesis in smooth muscle cells

1992 • 83 citations

Effects of endothelin on resistance arteries of DOCA-salt hypertensive rats

1992 • 82 citations

Production of Hypertension with Desoxycorticosterone Acetate-Impregnated Silicone Rubber Implants

1973 • 80 citations

Effects of Endothelin-1 and Vasopressin on Resistance Arteries of Spontaneously Hypertensive Rats

1992 • 72 citations

Molecular and cellular biology of endothelin and its receptors???Part I

1993 • 70 citations

DOCA-Salt Induced Malignant Hypertension in Spontaneously Hypertensive Rats

1984 • 63 citations

Effect of Hypertension Induced by Nitric Oxide Synthase Inhibition on Structure and Function of Resistance Arteries in the Rat

1993 • 55 citations

Endothelin vascular receptors and responses in deoxycorticosterone acetate-salt hypertensive rats.

1992 • 52 citations

Effects of candidate autocrine and paracrine mediators on growth responses in isolated rat arteries.

1994 • 25 citations

Contractile responses and signal transduction of endothelin-1 in aorta and mesenteric vasculature of adult spontaneously hypertensive rats

1993 • 25 citations