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1999 • 1,537 citations

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2004 • 926 citations

Specific immune-based diagnosis of tuberculosis

2000 • 910 citations

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2001 • 761 citations

How can immunology contribute to the control of tuberculosis?

2001 • 721 citations

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2001 • 720 citations

Guidelines for Using the QuantiFERON-TB Gold Test for Detecting Mycobacterium tuberculosis Infection, United States

2005 • 701 citations

Specific Detection of Tuberculosis Infection

2004 • 663 citations

Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak

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Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis: a prospective study

2006 • 505 citations

Interpretation of Repeated Tuberculin Tests

1999 • 495 citations

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Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG

1996 • 459 citations

Discrepancy Between the Tuberculin Skin Test and the Whole-Blood Interferon γ Assay for the Diagnosis of Latent Tuberculosis Infection in an Intermediate Tuberculosis-Burden Country

2005 • 439 citations

Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells

2001 • 406 citations

Direct Ex Vivo Analysis of Antigen-Specific IFN-γ-Secreting CD4 T Cells in Mycobacterium tuberculosis-Infected Individuals: Associations with Clinical Disease State and Effect of Treatment

2001 • 355 citations

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1995 • 346 citations

Correlation of ESAT-6-Specific Gamma Interferon Production with Pathology in Cattle followingMycobacterium bovisBCG Vaccination against Experimental Bovine Tuberculosis

2002 • 345 citations

Mycobacterium tuberculosis Infection in Health Care Workers in Rural India

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Comparison of Tuberculin Skin Test and New Specific Blood Test in Tuberculosis Contacts

2004 • 342 citations

Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells

2002 • 322 citations

Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence

2005 • 301 citations

Human T Cell Responses to the ESAT‐6 Antigen fromMycobacterium tuberculosis

1999 • 301 citations

Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study

2005 • 289 citations

Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis

2006 • 267 citations

Serial Testing of Health Care Workers for Tuberculosis Using Interferon-γ Assay

2006 • 267 citations

Comparison of Two Interferon-γ Assays and Tuberculin Skin Test for Tracing Tuberculosis Contacts

2006 • 266 citations

Immune Responses to the Mycobacterium tuberculosis -Specific Antigen ESAT-6 Signal Subclinical Infection among Contacts of Tuberculosis Patients

2002 • 257 citations

Exchanging ESAT6 with TB10.4 in an Ag85B Fusion Molecule-Based Tuberculosis Subunit Vaccine: Efficient Protection and ESAT6-Based Sensitive Monitoring of Vaccine Efficacy

2005 • 251 citations

Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6

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Use of a T Cell–Based Assay for Monitoring Efficacy of Antituberculosis Therapy

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Recognition of Stage-Specific Mycobacterial Antigens Differentiates between Acute and Latent Infections with Mycobacterium tuberculosis

2006 • 190 citations

Healthy Individuals That Control a Latent Infection with Mycobacterium tuberculosis Express High Levels of Th1 Cytokines and the IL-4 Antagonist IL-4δ2

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T-cell proliferative response to antigens secreted by Mycobacterium tuberculosis

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Differentiation betweenMycobacterium bovisBCG-Vaccinated andM. bovis-Infected Cattle by Using Recombinant Mycobacterial Antigens

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Association of Tuberculin-Boosted Antibody Responses with Pathology and Cell-Mediated Immunity in Cattle Vaccinated with Mycobacterium bovis BCG and Infected with M. bovis

2004 • 134 citations

Enzyme-linked Immunospot and Tuberculin Skin Testing to Detect Latent Tuberculosis Infection

2005 • 127 citations

A DNA Prime- Mycobacterium bovis BCG Boost Vaccination Strategy for Cattle Induces Protection against Bovine Tuberculosis

2003 • 126 citations

Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count

2005 • 125 citations

Reversion of the ELISPOT test after treatment in Gambian tuberculosis cases

2006 • 123 citations

Screening for Tuberculosis Infection Using Whole-Blood Interferon-γ and Mantoux Testing Among Japanese Healthcare Workers

2006 • 123 citations

Vaccines for Tuberculosis: Novel Concepts and Recent Progress

2005 • 117 citations

Comparison of Enzyme-Linked Immunospot Assay and Tuberculin Skin Test in Healthy Children Exposed to Mycobacterium tuberculosis

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Assessing the Serodiagnostic Potential of 35 Mycobacterium tuberculosis Proteins and Identification of Four Novel Serological Antigens

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Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons

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Persistence and Turnover of Antigen-Specific CD4 T Cells During Chronic Tuberculosis Infection in the Mouse

2003 • 87 citations

Cost-optimisation of screening for latent tuberculosis in close contacts

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Effect of Growth State on Transcription Levels of Genes Encoding Major Secreted Antigens of Mycobacterium tuberculosis in the Mouse Lung

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Potential value of serology for diagnosis of extrapulmonary tuberculosis

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Quantitative T Cell Assay Reflects Infectious Load of Mycobacterium tuberculosis in an Endemic Case Contact Model

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Induction of the Antigen 85 Complex ofMycobacterium tuberculosisin Sputum: A Determinant of Outcome in Pulmonary Tuberculosis Treatment

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Tuberculin skin test: estimation of positive and negative predictive values from routine data.

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Detection of Mycobacterium tuberculosis Antigens in Urinary Proteins of Tuberculosis Patients

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IMMUNE CORRELATES OF ACUTE MYCOBACTERIUM TUBERCULOSIS INFECTION IN HOUSEHOLD CONTACTS IN KAMPALA, UGANDA

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Evaluation of an In Vitro Assay for Gamma Interferon Production in Response to Mycobacterium tuberculosis Infections

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Risk of Active Tuberculosis Among Schoolchildren in Hong Kong

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Mycobacterial skin tests in humans 12 years after infection with Mycobacterium marinum.

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Tuberculin reactivity and subsequent development of tuberculosis in a cohort of student nurses.

1999 • 6 citations