Renoprotection by Rosiglitazone in Accelerated Type 2 Diabetic Nephropathy: Role of STAT1 Inhibition and Nephrin Restoration

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1985 • 29,733 citations

Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

2001 • 7,165 citations

Podocyte loss and progressive glomerular injury in type II diabetes.

1997 • 1,059 citations

Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage

1992 • 951 citations

The Role of Inflammatory Cytokines in Diabetic Nephropathy

2008 • 867 citations

Mouse Models of Diabetic Nephropathy

2009 • 865 citations

RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy

2003 • 579 citations

From the Periphery of the Glomerular Capillary Wall Toward the Center of Disease

2005 • 551 citations

Macrophages in mouse type 2 diabetic nephropathy: Correlation with diabetic state and progressive renal injury

2003 • 518 citations

Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice

2005 • 421 citations

Nephrin Expression Is Reduced in Human Diabetic Nephropathy

2003 • 338 citations

Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes

2003 • 293 citations

Role of High Glucose-Induced Nuclear Factor-κB Activation in Monocyte Chemoattractant Protein-1 Expression by Mesangial Cells

2002 • 269 citations

Intercellular Adhesion Molecule-1 Deficiency Is Protective against Nephropathy in Type 2 Diabetic db/db Mice

2005 • 267 citations

Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo

2003 • 264 citations

Protection of the kidney by thiazolidinediones: An assessment from bench to bedside

2006 • 214 citations

Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

2006 • 191 citations

Suppressors of Cytokine Signaling Abrogate Diabetic Nephropathy

2010 • 166 citations

Urinary levels of monocyte chemoattractant protein‐1 (MCP‐1) and interleukin‐8 (IL‐8), and renal injuries in patients with type 2 diabetic nephropathy

2002 • 139 citations

PPAR-γ agonist protects podocytes from injury

2007 • 119 citations

Rosiglitazone decreases albuminuria in type 2 diabetic patients

2007 • 109 citations

Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli

2004 • 109 citations

Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis

2006 • 104 citations

Kidney morphological changes in relation to long-term renal function and metabolic control in adolescents with IDDM

1998 • 102 citations

Altered Gene Expression Related to Glomerulogenesis and Podocyte Structure in Early Diabetic Nephropathy of db/db Mice and Its Restoration by Pioglitazone

2006 • 96 citations

Mechanical Stretch Induces Monocyte Chemoattractant Activity via an NF-κB-Dependent Monocyte Chemoattractant Protein-1-Mediated Pathway in Human Mesangial Cells

2005 • 90 citations

The Role of Interstitial Macrophages in Nephropathy of Type 2 Diabetic db/db Mice

2007 • 90 citations

High Glucose Augments the Angiotensin II-induced Activation of JAK2 in Vascular Smooth Muscle Cells via the Polyol Pathway

2003 • 79 citations

Transcriptional Regulation of Nephrin Gene by Peroxisome Proliferator–Activated Receptor-γ Agonist

2006 • 78 citations

Activation of Tubular Epithelial Cells in Diabetic Nephropathy and the Role of the Peroxisome Proliferator–Activated Receptor-γ Agonist

2006 • 74 citations

Bradykinin and high glucose promote renal tubular inflammation

2009 • 69 citations

Potentiation by candesartan of protective effects of pioglitazone against type 2 diabetic cardiovascular and renal complications in obese mice

2010 • 58 citations

PPARγ ligand attenuates PDGF-induced mesangial cell proliferation: Role of MAP kinase

2003 • 54 citations

Stretch reduces nephrin expression via an angiotensin II-AT₁-dependent mechanism in human podocytes: effect of rosiglitazone

2009 • 54 citations

Angiotensin converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy

2007 • 39 citations

Activation of PKC-β_Iin glomerular mesangial cells is associated with specific NF-κB subunit translocation

2001 • 35 citations

Use of genetic mouse models in the study of diabetic nephropathy

2004 • 29 citations

15-Deoxy- 12,14-prostaglandin J2 inhibits INF- -induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells

2008 • 24 citations

Glomerular Lesions in Unilateral Nephrectomized and Diabetic(UN-D) Mice.

1992 • 18 citations