Studies of the Binding and Biological Actions of Ethidium

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Structural considerations in the interaction of DNA and acridines

1961 • 2,199 citations

General Nature of the Genetic Code for Proteins

1961 • 1,347 citations

Ethidium bromide induced mutation of yeast mitochondria: Complete transformation of cells into respiratory deficient non-chromosomal “petites”

1968 • 504 citations

Enhanced sensitivity of 32P-postlabeling analysis of aromatic carcinogen:DNA adducts.

1985 • 476 citations

Visualization of drug-nucleic acid interactions at atomic resolution

1977 • 226 citations

Mutagenesis of bacteriophage T4 by acridines

1961 • 189 citations

Selective covalent binding of an ethidium analog to mitochondrial DNA with production of petite mutants in yeast by photoaffinity labeling

1975 • 123 citations

Biogenesis of mitochondria

1972 • 118 citations

A method for the measurement of the infectivity of trypanosome suspensions

1963 • 94 citations

Direct Demonstration of the Mutagenic Action of Euflavine on Baker's Yeast

1950 • 79 citations

Ethidium bromide and its photoreactive analogs: spectroscopic anlysis of deoxyribonucleic acid binding properties

1981 • 75 citations

Molecular Mechanisms of Mitochondrial Genetic Activity

1974 • 68 citations

EFFECT OF ACRIFLAVIN ON THE KINETOPLAST OF LEISHMANIA TARENTOLAE

1968 • 64 citations

Comparative studies of the binding of ethidium bromide and its photoreactive analogs to nucleic acids by fluorescence and rapid kinetics

1980 • 59 citations

Chemical Mutagenesis in Bacteriophage T2

1953 • 57 citations

Synthesis, separation and characterization of the mono- and diazide analogs of ethidium bromide

1977 • 54 citations

A novel reaction of mitochondrial DNA with ethidium bromide

1974 • 53 citations

Conditions that prevent ϱ−-induction by ethidium bromide

1971 • 52 citations

EVIDENCE FOR THE RETENTION OF KINETOPLAST DNA IN AN ACRIFLAVINE-INDUCED DYSKINETOPLASTIC STRAIN OF TRYPANOSOMA BRUCEI WHICH REPLICATES THE ALTERED CENTRAL ELEMENT OF THE KINETOPLAST

1971 • 50 citations

The mitochondrial genome of wild-type yeast cells

1979 • 49 citations

Production of frameshift mutations in salmonella by a light sensitive azide analog of ethidium

1976 • 47 citations

Bypass by photoaffinity labeling of blocked metabolic activation of ethidium: Confirmation of the role for covalent ethidium attachment in mitochondrial mutagenesis

1975 • 44 citations

Direct in vitro photoaffinity labeling of DNA with daunorubicin, adriamycin, and rubidazone

1979 • 40 citations

Acridine structure correlated with mutagenic activity in salmonella

1980 • 31 citations

Induction of respiratory deficient mutants in Saccharomyces cerevisiae by mono- and diazido analogs of ethidium

1977 • 29 citations

Ethidium binding to deoxyribonucleic acid: Spectrophotometric analysis of analogs with amino, azido, and hydrogen substituents

1984 • 26 citations

Photolytic binding of the monoazido analog of ethidium to yeast mitochondrial DNA: Competition by ethidium

1978 • 25 citations

Structure-function characterization for ethidium photoaffinity labels as mutagens in salmonella

1980 • 25 citations

Preferential delection of a specific region of mitochondrial DNA in Saccharomyces cerevisiae by ethidium bromide and 3-carbethoxy-psoralen

1978 • 22 citations

REPAIR SYNTHESIS IN HUMAN LYMPHOCYTES PROVOKED BY PHOTOLYSIS OF ETHIDIUM AZIDE

1977 • 20 citations

Covalent binding of ethidium azide analogs to Salmonella DNA in vivo: Competition by ethidium bromide

1979 • 19 citations

Antitrypanosomal Action Enhanced by Photoaffinity Labeling with Ethidium Analogs

1981 • 15 citations

Comparison of petite induction in yeast by acridines, ethidium and their photoaffinity probes

1981 • 14 citations

Identification of an acridine photoaffinity probe for trypanocidal action

1984 • 13 citations

The Trypanocidal Action of Phenanthridine Compounds

1952 • 13 citations

Induction of petite “mutants” in an ethidium-resistant strain of Saccharomyces cerevisiae by photoaffinity labeling

1981 • 10 citations

Azido analogs of acridine: Photoaffinity probes for frameshift mutagenesis in Salmonella typhimurium

1981 • 10 citations

Induction of cytoplasmically inherited respiration-deficient (‘petite’) mutants by photodynamic action of acridine compounds

1984 • 10 citations

Conversion of a powerful frameshifter acridine to a base-pair substitution analog

1979 • 8 citations

Monoazido analog of ethidium as a chromatin probe: Binding to DNA

1984 • 5 citations

Subcellular Localization of Photoreactive Ethidium Analogs in Trypanosoma brucei by Fluorescence Microscopy

1984 • 5 citations