2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability
Data up to Jan 2025
Total Citations Per Year
Abstract
References (10)
3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus
1994 • 270 citations
LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors
1997 • 223 citations
Agonist analysis of 2‐(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells
1992 • 189 citations
Induction or protection of limbic seizures in mice by mGluR subtype selective agonists
1995 • 140 citations
Selective activation of phosphoinositide hydrolysis by a rigid analogue of glutamate
1990 • 92 citations
1S,3R-ACPD-sensitive (metabotropic) [3H]glutamate receptor binding in membranes
1992 • 43 citations
Distribution and Ontogeny of 1S,3R‐1‐Aminocyclopentane‐1,3‐Dicarboxylic Acid‐Sensitive and Quisqualate‐Insensitive [3H]Glutamate Binding Sites in the Rat Brain
1994 • 42 citations
Synthesis of α,α-dialkylated amino acids with adenine or thymine residues a new mild and facile hydrolysis of hydantoins
1994 • 42 citations
Second-messenger responses in brain slices to elucidate novel glutamate receptors
1995 • 30 citations
Agonists and Antagonists for Metabotropic Glutamate Receptors
1995 • 12 citations