Antianginal effects of hydroxyfasudil, a Rho‐kinase inhibitor, in a canine model of effort angina

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 4,109 citations

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 3,002 citations

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

1999 • 1,581 citations

Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm

1999 • 312 citations

Rho kinase inhibitor HA-1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells

2000 • 210 citations

Rho-Kinase Is Involved in Macrophage-Mediated Formation of Coronary Vascular Lesions in Pigs In Vivo

2000 • 193 citations

Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage

2001 • 157 citations

Mechanism of action of a novel antivasospasm drug, HA1077.

1987 • 154 citations

Enhanced Myosin Light Chain Phosphorylations as a Central Mechanism for Coronary Artery Spasm in a Swine Model With Interleukin-1β

1997 • 153 citations

Rho‐kinase in human neutrophils: a role in signalling for myosin light chain phosphorylation and cell migration

1999 • 150 citations

Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase

1989 • 132 citations

Inhibition of Neutrophil Migration by a Protein Kinase Inhibitor for the Treatment of Ischemic Brain Infarction

1999 • 103 citations

The Kinase Inhibitor Fasudil (HA-1077) Reduces Intimal Hyperplasia through Inhibiting Migration and Enhancing Cell Loss of Vascular Smooth Muscle Cells

1999 • 52 citations

Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle

1998 • 43 citations

Comparative Pharmacological Properties among Calcium Channel Blockers: T-Channel versus L-Channel Blockade

1998 • 38 citations

The Protein Kinase Inhibitor Fasudil Protects Against Ischemic Myocardial Injury Induced by Endothelin-1 in the Rabbit

2000 • 31 citations

Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: Focus on felodipine

1995 • 29 citations

Relationship Between Plasma Diltiazem and Cardiovascular Responses in Conscious Dogs

1983 • 20 citations

Angina pectoris in patients with a history of myocardial infarction

1996 • 9 citations

Antiischemic Effects of CP-060S, an Inhibitor of Pathologically Modified Sodium Channels, Assessed in the Canine Experimental Model of Angina Pectoris

1999 • 8 citations

CARDIOVASCULAR EFFECTS OF DILTIAZEM IN THE DOG

1988 • 7 citations

Optimum treatment of stable angina pectoris.

1998 • 4 citations

Pharmacological and therapeutic basis for combined administration of beta blockers and calcium channel blockers in the treatment of stable chronic angina.

1997 • 3 citations