The conformational analysis of peptides using fourier transform IR spectroscopy

Examination of the secondary structure of proteins by deconvolved FTIR spectra

1986 • 2,865 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

Internal Reflection Spectroscopy

1968 • 1,758 citations

Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment

1993 • 1,489 citations

Internal Reflection Spectroscopy

1967 • 1,471 citations

Protein secondary structures in water from second-derivative amide I infrared spectra

1990 • 1,271 citations

New insight into protein secondary structure from resolution-enhanced infrared spectra

1988 • 1,248 citations

Structural characteristics of .alpha.-helical peptide molecules containing Aib residues

1990 • 960 citations

A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-Å resolution

1982 • 710 citations

[13] Resolution-enhanced fourier transform infrared spectroscopy of enzymes

1986 • 690 citations

Sequence of a Probable Potassium Channel Component Encoded at Shaker Locus of Drosophila

1987 • 645 citations

Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K ⁺ Channel

1991 • 634 citations

Quantitative IR spectrophotometry of peptide compounds in water (H₂O) solutions. I. Spectral parameters of amino acid residue absorption bands

1990 • 572 citations

Analysis of protein circular dichroism spectra for secondary structure using a simple matrix multiplication

1986 • 549 citations

Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.

1988 • 526 citations

Normal Vibrations of N-Methylacetamide

1958 • 499 citations

Estimation of amino acid residue side‐chain absorption in the infrared spectra of protein solutions in heavy water

1975 • 470 citations

The biophysics of peptide models of ion channels

1991 • 446 citations

Alteration of ionic selectivity of a K+ channel by mutation of the H5 region

1991 • 445 citations

Model calculations on the amide-I infrared bands of globular proteins

1992 • 441 citations

Determination of the secondary structure content of proteins in aqueous solutions from their amide I and amide II infrared bands. Comparison between classical and partial least-squares methods

1990 • 412 citations

Molecular biology of voltage-dependent potassium channels

1992 • 412 citations

Infrared Spectra and Protein Conformations in Aqueous Solutions

1967 • 408 citations

Exchange of Conduction Pathways Between Two Related K ⁺ Channels

1991 • 387 citations

Atomic scale structure and functional models of voltage-gated potassium channels

1992 • 332 citations

Pursuing the structure and function of voltage-gated channels

1990 • 323 citations

Infrared Membrane Spectroscopy

1981 • 321 citations

Model ion channels: Gramicidin and alamethicin

1992 • 314 citations

Studies of peptides forming 310- and .alpha.-helixes and .beta.-bend ribbon structures in organic solution and in model biomembranes by Fourier transform infrared spectroscopy

1991 • 293 citations

Magainins and the disruption of membrane-linked free-energy transduction.

1989 • 289 citations

Orientation of melittin in phospholipid bilayers. A polarized attenuated total reflection infrared study

1991 • 289 citations

PROTEIN-LIPID INTERACTIONS

1977 • 281 citations

Synthetic magainin analogues with improved antimicrobial activity

1988 • 277 citations

Structure of Synthetic Polypeptides

1950 • 275 citations

Redox‐linked conformational changes in proteins detected by a combination of infrared spectroscopy and protein electrochemistry

1990 • 262 citations

Determination of protein secondary structure using factor analysis of infrared spectra

1990 • 260 citations

Correlation of Infrared Stretching Frequencies and Hydrogen Bond Distances in Crystals

1956 • 250 citations

Fourier Transform Infrared Techniques for Probing Membrane Protein Structure

1988 • 248 citations

On the Spectral Subtraction of Water from the FT-IR Spectra of Aqueous Solutions of Proteins

1989 • 222 citations

Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers

1989 • 221 citations

Comparison of the conformation and orientation of alamethicin and melittin in lipid membranes

1987 • 213 citations

A two‐dimensional NMR study of the antimicrobial peptide magainin 2

1988 • 210 citations

Short alanine-based peptides may form 310-helices and not α-helices in aqueous solution

1992 • 205 citations

The three‐dimensional structure of porin from Rhodobacter capsulatus at 3 Å resolution

1990 • 204 citations

Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.

1990 • 200 citations

Conformation of pleionomers of .alpha.-aminoisobutyric acid

1985 • 192 citations

Does Fourier-transform infrared spectroscopy provide useful information on protein structures?

1992 • 188 citations

Importance of Environment in Determining Secondary Structure in Proteins

1994 • 186 citations

Magainin 1-induced leakage of entrapped calcein out of negatively-charged lipid vesicles

1989 • 183 citations

Reaction-induced infrared difference spectroscopy for the study of protein function and reaction mechanisms

1993 • 180 citations

Estimation of protein secondary structure from the laser Raman amide I spectrum

1983 • 179 citations

Linear oligopeptides. 81. Solid-state and solution conformation of homooligo(.alpha.-aminoisobutyric acids) from tripeptide to pentapeptide: evidence for a 310 helix

1982 • 175 citations

Halogenated alcohols as solvents for proteins: FTIR spectroscopic studies

1992 • 172 citations

Conformational transitions in poly(l-lysine): studies using Fourier transform infrared spectroscopy

1989 • 167 citations

Protein secondary structure from fourier transform infrared spectroscopy: A data base analysis

1991 • 156 citations

Intensities and other spectral parameters of infrared amide bands of polypeptides in the β‐ and random forms

1973 • 155 citations

Fourier transform infrared spectroscopic studies of calcium-binding proteins

1991 • 146 citations

Infrared spectroscopic studies of biomembranes and model membranes

1986 • 142 citations

Raman spectroscopy of synthetic antimicrobial frog peptides magainin 2a and PGLa

1990 • 139 citations

A Fourier transform infrared investigation of the structural differences between ribonuclease A and ribonuclease S

1986 • 135 citations

Protein Secondary Structure from Fourier Transform Infrared and/or Circular Dichroism Spectra

1993 • 122 citations

Attenuated total reflectance Fourier transform infrared studies of the interaction of melittin, two fragments of melittin, and .delta.-hemolysin with phosphatidylcholines

1987 • 109 citations

An Algorithm for the Reproducible Spectral Subtraction of Water from the FT-IR Spectra of Proteins in Dilute Solutions and Adsorbed Monolayers

1986 • 101 citations

Characterization of β‐turns in cyclic hexapeptides in solution by fourier transform IR spectroscopy

1993 • 97 citations

Conformation of magainin-2 and related peptides in aqueous solution and membrane environments probed by Fourier transform infrared spectroscopy

1992 • 90 citations

Vibrational analysis of peptides, polypeptides, and proteins. XVIII. Conformational sensitivity of the α‐helix spectrum: α_I‐ and α_II‐Poly(<scp>L</scp>‐alanine)

1984 • 86 citations

Infrared spectroscopic discrimination between α‐ and 3₁₀‐helices in globular proteins

1991 • 86 citations

Critical Main-Chain Length for Conformational Conversion From 3₁₀-Helix to α-Helix in Polypeptides

1990 • 84 citations

Structure of conformationally constrained peptides: From model compounds to bioactive peptides

1989 • 81 citations

Infrared spectroscopic discrimination between alpha- and 3(10)-helices in globular proteins. Reexamination of Amide I infrared bands of alpha-lactalbumin and their assignment to secondary structures.

1991 • 80 citations

Study of the adriamycin-cardiolipin complex structure using attenuated total reflection infrared spectroscopy

1987 • 72 citations

The molecular biology of K+ channels

1991 • 67 citations

Role of disulfide linkages in tachyplesin-lipid interactions

1993 • 65 citations

Mechanisms of antibacterial action of tachyplesins and polyphemusins, a group of antimicrobial peptides isolated from horseshoe crab hemocytes

1992 • 64 citations

Fourier transform infrared spectra of the polypeptide alamethicin and a possible structural similarity with bacteriorhodopsin

1988 • 61 citations

Delta-Sleep-Inducing Peptide: Solution Conformational Studies of a Membrane-Permeable Peptide

1994 • 56 citations

An SS1–SS2 β-barrel structure for the voltage-activated potassium channel

1992 • 52 citations

Design and synthesis of basic peptides having amphipathic β-structure and their interaction with phospholipid membranes

1990 • 43 citations

Linear oligopeptides. Part 227. X-Ray crystal and molecular structures of two α-helix-forming (Aib-<scp>L</scp>-Ala)sequential oligopeptides, pBrBz-(Aib-<scp>L</scp>-Ala)₅-OMe and pBrBz-(Aib-<scp>L</scp>-Ala)₆-OMe

1990 • 42 citations

The conformation of dynorphin A-(1–13) in aqueous solution as studied by fourier transform infrared spectroscopy

1989 • 40 citations

Vibrational analysis of peptides, polypeptides, and proteins. XXIV. Conformation of poly(α‐aminoisobutyric acid)

1984 • 38 citations

Ca2+ release from caged-Ca2+ alters the FTIR spectrum of sarcoplasmic reticulum

1991 • 35 citations

Studies of the pore-forming domain of a voltage-gated potassium channel protein

1994 • 26 citations

Molecular reaction mechanism of photosynthetic proteins as determined by FTIR-spectroscopy

1992 • 20 citations

Chapter 13 Infrared spectroscopic studies of lipid-protein interactions in membranes

1993 • 16 citations

Membrane protein conformation as determined by Fourier transform-infra-red spectroscopy

1989 • 12 citations

Molecular reaction mechanism of photosynthetic proteins as determined by FTIR-spectroscopy

1992 • 12 citations

CD and FTIR studies of an immunogenic disulphide cyclized octadecapeptide, a fragment of a snake curaremimetic toxin

1993 • 8 citations

Problems And Caveats Associated With The Determination Of Protein Conformation By FT-IR Spectroscopy

1989 • 5 citations