Genomic organization and structure of Bruton agammaglobulinemia tyrosine kinase: localization of mutations associated with varied clinical presentations and course in X chromosome-linked agammaglobulinemia.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1993 • 1,438 citations

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1993 • 1,338 citations

An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus

1988 • 1,140 citations

Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

1993 • 868 citations

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1992 • 684 citations

Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes

1993 • 631 citations

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

1993 • 497 citations

The CBA/N Mouse Strain: An Experimental Model Illustration the Influence of the X-Chromosome on Immunity

1982 • 305 citations

Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells.

1994 • 301 citations

Agammaglobulinemia.

1952 • 269 citations

Phenotypic features and proliferative activity of B cell progenitors in X-linked agammaglobulinemia.

1990 • 152 citations

Molecular Approaches to Analysis of X-Linked Immunodeficiencies

1992 • 139 citations

Mutation analysis of the Bruton's tyrosine kinase gene in X-linked agammaglobulinemia: identification of a mutation which affects the same codon as is altered in immunodeficient xid mice

1994 • 131 citations

Mapping of the X-linked agammaglobulinemia locus by use of restriction fragment-length polymorphism.

1986 • 123 citations

Mutation detection in the X-linked agammaglobulinemia gene, BTK, using single strand conformation polymorphism analysis

1994 • 101 citations

TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12

1994 • 86 citations

Mapping of a gene for X-linked agammaglobulinemia and evidence for genetic heterogeneity

1986 • 64 citations

Identification of a closely linked DNA marker, DXS178, to further refine the X-linked agammaglobulinemia locus

1990 • 61 citations

Close linkage of probe p212 (DXS178) to X-linked agammaglobulinemia

1989 • 60 citations

Close linkage of random DNA fragments from Xq 21.3–22 to X-linked agammaglobulinaemia (XLA)

1987 • 57 citations

Structure of the human lck gene: differences in genomic organisation within src-related genes affect only N-terminal exons

1989 • 32 citations

Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome.

1993 • 32 citations