Does insulin act directly on the brain to increase tryptophan levels?

Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

1971 • 1,671 citations

Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids

1972 • 1,164 citations

Handbook of Neurochemistry

1969 • 940 citations

Rapid method for the determination of 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in small regions of rat brain

1970 • 937 citations

The determination of tryptophan in plasma, liver, and urine.

1967 • 826 citations

Brain Serotonin Content: Increase Following Ingestion of Carbohydrate Diet

1971 • 721 citations

Amino acid metabolism during prolonged starvation

1969 • 708 citations

Error in the determination of tryptophan by the method of Denkla and Dewey. A revised procedure

1974 • 423 citations

KINETICS OF COMPETITIVE INHIBITION OF NEUTRAL AMINO ACID TRANSPORT ACROSS THE BLOOD‐BRAIN BARRIER

1977 • 357 citations

Light and Electron Microscopy of Lesions in Rats Rendered Diabetic with Streptozotocin

1967 • 247 citations

SYNTHETIC AMINO ACIDS AND THE NATURE OF <scp>l</scp>‐DOPA TRANSPORT AT THE BLOOD‐BRAIN BARRIER

1975 • 210 citations

EFFECT OF ALBUMIN BINDING AND AMINO ACID COMPETITION ON TRYPTOPHAN UPTAKE INTO BRAIN

1977 • 200 citations

A quantitative rotational model for studying serotonergic function in the rat

1977 • 179 citations

Relevance of free tryptophan in serum to tissue tryptophan concentrations

1974 • 161 citations

EFFECTS OF INSULIN AND STREPTOZOTOCIN–NDUCED DIABETES ON BRAIN TRYPTOPHAN AND SEROTONIN METABOLISM IN RATS

1978 • 120 citations

Acute reduction of brain serotonin and 5-HIAA following food consumption: Correlation with the ratio of serum tryptophan to the sum of competing neutral amino acids

1975 • 68 citations

INSULIN AND THE WAY THE BRAIN HANDLES GLUCOSE¹

1975 • 66 citations

Action of Insulin on Transport of l-Alanine into Rat Diaphragm in Vitro

1973 • 65 citations

Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum neutral amino acids

1976 • 65 citations

Nutritional aspects of amino acid metabolism

1971 • 53 citations

Kidney function in experimental diabetic ketosis

1971 • 53 citations

Effect of L-leucine on amino acid levels in plasma and tissue of normal and diabetic rats

1968 • 43 citations

Effect of insulin on brain 5-hydroxytryptamine and 5-hydroxy-indole-acetic acid of rat

1970 • 37 citations

EFFECT OF INSULIN ON LEVELS AND TURNOVER OF INTERMEDIATES OF BRAIN CARBOHYDRATE METABOLISM IN VIVO

1971 • 33 citations

Possible role of insulin in the transport of tyrosine and tryptophan from blood to brain

1975 • 31 citations

Nutritional aspects of amino acid metabolism

1972 • 31 citations