Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils.

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1980 • 2,099 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes

1979 • 812 citations

Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine.

1978 • 454 citations

Role of Prostaglandins in Ulcerative Colitis

1978 • 376 citations

Therapeutic Efficacy of Sulfasalazine and Its Metabolites in Patients with Ulcerative Colitis and Crohn's Disease

1980 • 318 citations

Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

1979 • 297 citations

Generation of unique mono-hydroxy-eicosatetraenoic acids from arachidonic acid by human neutrophils.

1979 • 258 citations

Distribution Studies of Salicylazosulfapyridine and its Metabolites

1973 • 253 citations

Novel structural determinants of the human neutrophil chemotactic activity of leukotriene B.

1981 • 189 citations

Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils.

1980 • 186 citations

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

1980 • 118 citations

Stimulation of arachidonic acid metabolism in the polymorphonuclear leukocyte by an N-formylated peptide. Comparison with ionophore A23187.

1980 • 109 citations

Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates

1980 • 109 citations

Studies of prostaglandins and sulphasalazine in ulcerative colitis

1981 • 105 citations