Single Amino Acid Substitutions in κ-Conotoxin PVIIA Disrupt Interaction with the Shaker K+ Channel

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

1998 • 6,595 citations

Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.

1987 • 767 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

1995 • 559 citations

Diversity of Conus Neuropeptides

1990 • 537 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Revealing the Architecture of a K ⁺ Channel Pore Through Mutant Cycles with a Peptide Inhibitor

1995 • 434 citations

A unified nomenclature for short-chain peptides isolated from scorpion venoms: α-KTx molecular subfamilies

1999 • 374 citations

[16] Electrophysiologic recordings from Xenopus oocytes

1998 • 361 citations

The charybdotoxin family of K+ channel-blocking peptides

1995 • 341 citations

On the Convergent Evolution of Animal Toxins

1997 • 328 citations

E.E. Just Lecture, 1996

1997 • 326 citations

The charybdotoxin receptor of a Shaker K+ channel: Peptide and channel residues mediating molecular recognition

1994 • 286 citations

Strategy for rapid immobilization of prey by a fish-hunting marine snail

1996 • 265 citations

Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins

1995 • 253 citations

[19] Electrophysiological recording from Xenopus oocytes

1992 • 236 citations

Mechanism of charybdotoxin block of a voltage-gated K+ channel

1993 • 172 citations

Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.

1990 • 145 citations

μ-Conotoxin PIIIA, a New Peptide for Discriminating among Tetrodotoxin-Sensitive Na Channel Subtypes

1998 • 144 citations

κ-Conotoxin Pviia Is a Peptide Inhibiting theShaker K+ Channel

1998 • 138 citations

Structural Conservation of the Pores of Calcium-activated and Voltage-gated Potassium Channels Determined by a Sea Anemone Toxin

1999 • 129 citations

Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails

1998 • 119 citations

Three-Dimensional Structure of κ-Conotoxin PVIIA, a Novel Potassium Channel-Blocking Toxin from Cone Snails^,

1998 • 82 citations

Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA

1997 • 79 citations

A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity

1992 • 71 citations

[31] Conus peptides as probes for ion channels

1999 • 68 citations

Conantokin-G selectively inhibits N-methyl-D-aspartate-induced currents in Xenopus oocytes injected with mouse brain mRNA

1992 • 51 citations

Site-Directed Mutagenesis of Dendrotoxin K Reveals Amino Acids Critical for Its Interaction with Neuronal K⁺ Channels

1997 • 48 citations

The Block of Shaker K+ Channels by κ-Conotoxin Pviia Is State Dependent

1999 • 36 citations