mRNAs for plasma membrane calcium pump isoforms differing in their regulatory domain are generated by alternative splicing that involves two internal donor sites in a single exon.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

1987 • 2,353 citations

DNA cloning : a practical approach

1985 • 2,302 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

Two Ca2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences

1986 • 812 citations

Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA

1985 • 762 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Structure and function of proton translocating ATPase in plasma membranes of plants and fungi

1988 • 464 citations

Molecular cloning of the rat stomach (H+ + K+)-ATPase.

1986 • 463 citations

Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases.

1988 • 379 citations

Primary structure of the α-subunit of Torpedo californica (Na+ + K+)ATPase deduced from cDNA sequence

1985 • 375 citations

Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle.

1987 • 374 citations

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

1988 • 374 citations

Complete primary structure of a human plasma membrane Ca2+ pump.

1988 • 350 citations

Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase

1986 • 319 citations

Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase.

1985 • 302 citations

A novel Ca2+ pump expressed in brain, kidney, and stomach is encoded by an alternative transcript of the slow-twitch muscle sarcoplasmic reticulum Ca-ATPase gene. Identification of cDNAs encoding Ca2+ and other cation-transporting ATPases using an oligonucleotide probe derived from the ATP-binding site.

1988 • 268 citations

Identification and primary structure of a calmodulin binding domain of the Ca2+ pump of human erythrocytes.

1988 • 258 citations

The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.

1987 • 241 citations

DNA inversion within the apolipoproteins AI/CIII/AIV-encoding gene cluster of certain patients with premature atherosclerosis.

1987 • 154 citations

Primary structure of the cAMP-dependent phosphorylation site of the plasma membrane calcium pump

1989 • 138 citations

A rapid biochemical method for purifying lambda DNA from phage lysates

1986 • 72 citations