Specific Immunosuppression of Corneal Allograft Rejection by Combination of Anti-VLA-4 and Anti-LFA-1 Monoclonal Antibodies in Mice

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

1990 • 799 citations

Specific Acceptance of Cardiac Allograft After Treatment with Antibodies to ICAM-1 and LFA-1

1992 • 737 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

In vivo effects of monoclonal antibody to ICAM-1 (CD54) in nonhuman primates with renal allografts.

1990 • 369 citations

Factors Predictive of Corneal Graft Survival

1992 • 323 citations

Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation

1990 • 322 citations

The costimulatory function of antigen-presenting cells

1990 • 304 citations

ORTHOTOPIC CORNEAL TRANSPLANTATION IN MICE—EVIDENCE THAT THE IMMUNOGENETIC RULES OF REJECTION DO NOT APPLY

1992 • 298 citations

Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1.

1983 • 255 citations

Graft failure after penetrating keratoplasty

1990 • 251 citations

VLA-4 mediates CD3-dependent CD4+ T cell activation via the CS1 alternatively spliced domain of fibronectin.

1990 • 224 citations

Risk Factors of Corneal Graft Failure

1993 • 183 citations

PREVENTION OF GRAFT FAILURE BY AN ANTI-HLFA-1 MONOCLONAL ANTIBODY IN HLA-MISMATCHED BONE-MARROW TRANSPLANTATION

1986 • 147 citations

EFFECT OF ANTI-LFA1 (CD11a) MONOCLONAL ANTIBODIES IN ACUTE REJECTION IN HUMAN KIDNEY TRANSPLANTATION

1991 • 103 citations

Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies.

1994 • 85 citations

Report from the Australian Corneal Graft Registry.

1989 • 74 citations

A Method for Performing Full-Thickness, Orthotopic, Penetrating Keratoplasty in the Mouse

1990 • 62 citations

The efficacy of LFA-1 and VLA-4 antibody treatment in rat vascularized cardiac allograft rejection.

1993 • 56 citations

PROLONGATION OF RAT ISLET ALLOGRAFT SURVIVAL BY TREATMENT WITH MONOCLONAL ANTIBODIES AGAINST VLA-4 AND LFA-1

1995 • 55 citations

THE EFFICACY OF LFA-1 AND VLA-4 ANTIBODY TREATMENT IN RAT VASCULARIZED CARDIAC ALLOGRAFT REJECTION

1993 • 51 citations

Effect of LFA-1 and ICAM-1 antibody treatment on murine corneal allograft survival.

1994 • 39 citations

The role of lymphokine-activated cell-associated antigen

1987 • 21 citations

Suppression of corneal allograft rejection after penetrating keratoplasty by antibodies to ICAM-1 and LFA-1 in mice.

1995 • 12 citations

Effect of monoclonal antibody to VLA-4 on corneal allograft survival in mice.

1996 • 6 citations

Time course and localization of intercellular adhesion molecule-1 induction in kidney allografts in mice.

1994 • 6 citations

Cytokine expression in cardiac allografts in mice with peripheral tolerance induced by anti-ICAM-1 and anti-LFA-1 monoclonal antibodies.

1995 • 6 citations