Mutations in the EXT1 and EXT2 Genes in Hereditary Multiple Exostoses

The natural history of hereditary multiple exostoses.

1994 • 593 citations

Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)

1995 • 421 citations

The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

1996 • 331 citations

Hereditary multiple exostoses.

1991 • 305 citations

A gene for hereditary multiple exostoses maps to chromosome 19p

1994 • 211 citations

Positional cloning of a gene involved in hereditary multiple exostoses

1996 • 200 citations

Genetic heterogeneity in families with hereditary multiple exostoses.

1993 • 197 citations

Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8.

1995 • 194 citations

HEREDITARY MULTIPLE EXOSTOSIS.

1964 • 164 citations

Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11

1994 • 162 citations

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.

1997 • 147 citations

Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11.

1995 • 138 citations

Mutation Screening of the EXT1 and EXT2 Genes in Patients with Hereditary Multiple Exostoses

1997 • 130 citations

Identification of a Third EXT-like Gene (EXTL3) Belonging to the EXT Gene Family

1998 • 129 citations

Hereditary multiple exostoses (EXT): mutational studies of familial EXT1 cases and EXT-associated malignancies.

1997 • 128 citations

Molecular dissection of a contiguous gene syndrome: localization of the genes involved in the Langer--Giedion syndrome

1995 • 125 citations

Identification and characterization of a novel member of the EXT gene family, EXTL2.

1998 • 92 citations

Identification and Characterization of a Novel Member of the EXT Gene Family, EXTL2

1997 • 82 citations

Evaluation of locus heterogeneity and EXT1 mutations in 34 families with hereditary multiple exostoses

1998 • 71 citations

Refinement of the multiple exostoses locus (EXT2) to a 3-cM interval on chromosome 11.

1995 • 58 citations

Genomic Organization and Promoter Structure of the Human EXT1 Gene

1997 • 48 citations

Identification of novel mutations in the human EXT1 tumor suppressor gene

1997 • 41 citations

An extension of the admixture test for the study of genetic heterogeneity in hereditary multiple exostoses

1997 • 38 citations

Hereditary multiple exostoses: Confirmation of linkage to chromosomes 8 and 11

1996 • 24 citations

Hereditary multiple exostoses: Confirmation of linkage to chromosomes 8 and 11

1996 • 18 citations

New syndrome: Exostoses, anetodermia, brachydactyly

1984 • 18 citations