Nutritional support in the cancer-bearing host: Effects on host and tumor

Implications of Malnutrition in the Surgical Patient

1979 • 527 citations

PREOPERATIVE PARENTERAL FEEDING IN PATIENTS WITH GASTROINTESTINAL CARCINOMA

1982 • 487 citations

THE IMMEDIATE CAUSES OF DEATH IN CANCER

1932 • 418 citations

Prophylaxis of chemically induced benign and malignant epithelial tumors by vitamin A acid (retinoic acid)

1972 • 304 citations

Uncomplicated starvation versus cancer cachexia.

1977 • 293 citations

Total Parenteral Nutrition in the Cancer Patient

1981 • 271 citations

Cachexia, the Metabolic Component of Neoplastic Diseases

2015 • 261 citations

Nutrition in Relation to Cancer.

1948 • 256 citations

Energy Expenditure in Malnourished Cancer Patients

1983 • 235 citations

The effects of perioperative hyperalimentation on complications in patients with carcinoma and weight loss

1977 • 211 citations

Pre-operative intravenous feeding—a controlled trial

1979 • 206 citations

Lasting Influence of Early Caloric Restriction on Prevalence of Neoplasms in the Rat<xref ref-type="fn" rid="FN1">2</xref>

1971 • 196 citations

Energy and Nitrogen Metabolism in Cancer

1954 • 186 citations

Inhibition of carcinogenesis by retinoids.

1983 • 186 citations

Energy metabolism and requirements in the cancer patient.

1977 • 176 citations

The efficacy of nutritional assessment and support in cancer surgery

1981 • 175 citations

Nutrition as an adjunct to cancer treatment in the adult.

1977 • 166 citations

Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea

1977 • 159 citations

Cancer cachexia

1979 • 154 citations

Nutritional consequences of the radiotherapy of head and neck cancer

1983 • 153 citations

HYPOGLYCEMIA IN ASSOCIATION WITH EXTRAPANCREATIC TUMORS: DEMONSTRATION OF ELEVATED PLASMA NSILA–s BY A NEW RADIORECEPTOR ASSAY

1974 • 152 citations

Gluconeogenesis from alanine in patients with progressive malignant disease.

1979 • 150 citations

Influence of Protein Under- and Overnutrition on Spontaneous Tumor Prevalence in the Rat

1973 • 148 citations

Host-tumor interaction and nutrient supply

1980 • 145 citations

QUANTITATIVE EFFECTS OF NUTRITIONAL ESSENTIAL AMINO ACID DEFICIENCY UPON IMMUNE RESPONSES TO TUMORS IN MICE

1973 • 144 citations

Effects of nutrition on tumor growth and tolerance to chemotherapy

1975 • 142 citations

Pathogenesis of cachexia in cancer.A review and a hypothesis

1972 • 141 citations

Quantitative nutritional studies with water-soluble, chemically defined diets. VIII. The forced feeding of diets each lacking in one essential amino acid

1959 • 138 citations

Induction by dimethylhydrazine of intestinal carcinoma in normal rats and rats fed high or low levels of vitamin A.

1973 • 136 citations

NUTRITIONAL PROBLEMS OF SURGICAL PATIENTS

1955 • 136 citations

Nutrition and cancer : etiology and treatment

1981 • 135 citations

Nutritional consequences of radiotherapy.

1977 • 126 citations

Consequences of Malnutrition in the Surgical Patient

1981 • 126 citations

A controlled, prospective, randomized trial evaluating the metabolic effects of enteral and parenteral nutrition in the cancer patient

1982 • 125 citations

CANCER CACHEXIA AND GLUCONEOGENESIS

1974 • 124 citations

Current problems in cancer

2003 • 124 citations

Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer

1986 • 122 citations

Hyperalimentation of the cancer patient with protein-calorie undernutrition.

1981 • 121 citations

Some aspects of nitrogen and energy metabolism in cancerous subjects: a review.

1951 • 115 citations

Perioperative total parenteral nutrition in patients with gastrointestinal cancer

1981 • 114 citations

Changes in Body Composition in Patients with Small-Cell Lung Cancer

1984 • 113 citations

Suppression Of Ultraviolet Light-Induced Tumor Formation By Dietary Antioxidants

1975 • 111 citations

Total parenteral nutrition as an adjunct to chemotherapy of metastatic colorectal cancer.

1981 • 108 citations

The Glucose Metabolism of Patients with Malignant Disease and of Normal Subjects as Studied by Means of an Intravenous Glucose Tolerance Test12

1957 • 108 citations

Cachexia of malignancy.Potential role of insulin in nutritional management

1979 • 107 citations

Carbohydrate metabolism in subjects with cancer.

1971 • 107 citations

Parental nutrition: is it oncologically logical?

1984 • 103 citations

Effects of intake of L-ascorbic acid on the incidence of dermal neoplasms induced in mice by ultraviolet light.

1982 • 99 citations

Stimulation of Growth of a Transplantable Hepatoma in Rats by Parenteral Nutrition 2

1976 • 97 citations

The relationship between underfeeding and tumor formation, transplantation, and growth in rats and mice.

1961 • 94 citations

Anorexia in cancer patients.

1977 • 94 citations

HOW TUMORS AFFECT HOST METABOLISM*

1974 • 89 citations

Host and tumor responses to increasing levels of intravenous nutritional support.

1983 • 89 citations

Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide.

1976 • 88 citations

Effect of Essential Amino Acid Restriction on the Growth of Female C57BL Mice and Their Implanted BW10232 Adenocarcinomas

1971 • 86 citations

Nutrition and Cancer: Physiological Interrelationships

1985 • 86 citations

Effects of intravenous nutrition on tumor growth and host immunocompetence in malnourished animals.

1978 • 83 citations

Metabolic Response of Whole Body and Peripheral Tissues to Enteral Nutrition in Weight-Losing Cancer and Noncancer Patients

1983 • 82 citations

Effects of total parenteral nutrition and chemotherapy on the metabolic derangements in small cell lung cancer.

1984 • 79 citations

Carbohydrate metabolism in cancer cachexia.

1981 • 77 citations

Parenteral Nutrition in Esophageal Cancer Patients

1982 • 73 citations

A prospective, randomized study of adjuvant parenteral nutrition in the treatment of sarcomas: results of metabolic and survival studies.

1984 • 72 citations

The Effect of Dietary Protein Depletion on Immunocompetence

1974 • 68 citations

Inhibition of a Spectrum of Animal Tumors by Dietary Zinc Deficiency<xref ref-type="fn" rid="FN2">2</xref>

1972 • 67 citations

Tumor-caused changes in host protein synthesis under different dietary situations.

1976 • 66 citations

Protein synthesis dynamics in human gastrointestinal malignancies.

1980 • 65 citations

The effect of cancer on nitrogen, electrolyte, and mineral metabolism.

1977 • 64 citations

Anorexia-producing intermediary metabolites

1976 • 63 citations

Nutritional Support as an Adjunct to Radiation Therapy

1984 • 62 citations

Responses of hepatoma-bearing rats to total parenteral hyperalimentation and to ad libitum feeding

1977 • 60 citations

Oxygen consumption and anaerobic glycolysis of human malignant and normal tissue.

1962 • 60 citations

The effect of protein nutrition on host and tumor metabolism

1977 • 60 citations

Intravenous hyperalimentation as an adjunct to cancer chemotherapy with 5-fluorouracil

1975 • 58 citations

Nutritional aspects of cancer

1976 • 57 citations

Total parenteral nutrition (TPN) with complete nutritive mixtures: An artificial gut in cancer patients

1979 • 56 citations

Metabolism in peripheral tissues in cancer patients.

1981 • 54 citations

Systemic effects of tumors in force-fed rats.

1951 • 53 citations

Alteration of tumor cell kinetics by pulse total parenteral nutrition. Potential therapeutic implications

1984 • 52 citations

Effects of Protein Depletion and Repletion on Cell-mediated Immunity in Experimental Animals

1978 • 46 citations

Nutritional Problems Induced by Cancer

1979 • 46 citations

Intravenous nutrition and tumor host protein metabolism

1977 • 45 citations

Fatty acid mobilization and glucose metabolism in patients with cancer

1966 • 42 citations

Selective Metabolic and Chemotherapeutic Effects of Vitamin B6 Antimetabolites

1964 • 40 citations

Complete Regression of Lymphosarcoma Implants Following Temporary Induction of Riboflavin Deficiency in Mice.

1949 • 39 citations

DNA synthesis in rat sarcoma and liver: The effect of starvation

1977 • 38 citations

Correlation of changes in brain indoleamine metabolism with onset of anorexia in rats

1982 • 37 citations

Effects of nutritional repletion on host and tumor response to chemotherapy

1980 • 37 citations

Muscle activity, body fat, and induced rat mammary tumors.

1973 • 36 citations

Effects of nutritional depletion and repletion on plasma methotrexate pharmacokinetics

1984 • 36 citations

Adjuvant, pulse total parenteral nutrition and tumor response to cycle-specific and cycle-nonspecific chemotherapy.

1983 • 35 citations

Elemental Diet as an Adjuvant for Patients With Locally Advanced Gastrointestinal Cancer Receiving Radiation Therapy: A Prospectively Randomized Study

1978 • 34 citations

Experimental vitamin K deficiency and spontaneous metastases

1977 • 34 citations

Nutritional parameters affecting erythrocyte polyamine levels in cancer patients.

1984 • 33 citations

Nutritional support for cancer patients receiving abdominal and pelvic radiotherapy: a randomized prospective clinical experiment of intravenous versus oral feeding.

1978 • 32 citations

The effect of pyridoxine deficiency on mouse sarcoma 180.

1959 • 30 citations

Nutritional repletion of malnourished tumor-bearing and nontumor-bearing rats: Effects on body weight, liver, muscle, and tumor

1980 • 30 citations

Nutritional and Immunological Evaluations in Cancer Patients. Relationship to Surgical Infections

1980 • 30 citations

Metabolic effects of infused triglyceride.

1961 • 29 citations

Plasma and brain amino acids in Walker 256 carcinosarcoma-bearing rats.

1979 • 28 citations

Nitrogen metabolism in cancer patients.

1981 • 28 citations

Enhanced Tumor Response to Cycle‐Specific Chemotherapy by Parenteral Amino Acid Administration

1983 • 26 citations

The effects of nutrition and treatment of cancer on host immunocompetence.

1979 • 26 citations

Nutritional Responses of Tumor‐bearing Rats to Oral or Intravenous Feeding

1982 • 25 citations

Selective Inhibition of Growth and Respiration of Melanomas by Tyrosinase Inhibitors<xref ref-type="fn" rid="FN2">2</xref>

1965 • 22 citations

Effect of total parenteral nutrition on tumor-host responses in rats.

1981 • 21 citations

BASAL METABOLISM IN CHRONIC MYELOGENOUS LEUKEMIA

1927 • 21 citations

Hyperalimentation and immune competence in cancer.

1975 • 21 citations

Proceedings of the Federation of American Societies for Experimental Biology

1941 • 21 citations

Effect of malnutrition on methotrexate toxicity and tissue levels of dihydrofolate reductase in the rat.

1982 • 21 citations

Tumoricidal potential of nutritional manipulations.

1982 • 20 citations

Source of Tumor Proteins. I. Effect of a Low-Nitrogen Diet on the Establishment and Growth of a Transplanted Tumor<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1945 • 19 citations

Correlation of lysosomal enzymes and cachexia in the tumor-bearing rat

1979 • 19 citations

Nutritional manipulation of tumor-bearing animals: effects on body weight, serum protein levels, and tumor growth.

1978 • 19 citations

The effect of protein depletion on the host response to transplantable rat tumor Walker 256.

1950 • 19 citations

Cell-Mediated Cytotoxicity Against HeLa Cells in Patients With Invasive or Preinvasive Cervical Cancer 2

1973 • 18 citations

The Basal Metabolism in Myelogenous Leukemia and Its Relation to the Blood Findings

1921 • 17 citations

The effects of dietary deficiencies of magnesium and potassium on the growth and chemistry of transplanted tumours and host tissues in the rat

1977 • 17 citations

Enhanced tumor response to cycle-specific chemotherapy by pulse total parenteral nutrition

1985 • 16 citations

Nutritional factors in the design of more selective antitumor agents.

1969 • 15 citations

The Influence of Dietary Protein on the Metabolism of Ribonucleic Acid in Rat Hepatoma

1959 • 15 citations

THE EFFECT OF A PHENYLALANINE‐TYROSINE LOW DIET ON THE GROWTH AND MORPHOLOGY OF TRANSPLANTABLE MALIGNANT MELANOMAS OF THE SYRIAN GOLDEN HAMSTER (MESOCRICETUS AURATUS)

1973 • 14 citations

Parenteral nutrition and human gastrointestinal tumor protein metabolism

1982 • 14 citations

Elemental diet as an adjuvant for patients with locally advanced gastrointestinal cancer receiving radiation therapy: a prospectively randomized study

1978 • 13 citations

Protein-calorie malnutrition in patients with colorectal cancer

1978 • 13 citations

Total Parenteral Nutrition with and without Fat as Substrate for Growth of Rats and Transplanted Hepatocarcinoma

1985 • 13 citations

Effects of magnesium and potassium deficiencies on composition and growth of ascites tumour cells

1969 • 12 citations

Effects of enteral and parenteral nutrition on tumor response to chemotherapy in experimental animals

1981 • 11 citations

Effect of B6 deficiency on hepatoma 7794A growth rate: Activities of tyrosine transaminase and serine dehydratase before and after induction by hydrocortisone

1974 • 10 citations

Nutritional support and the immune system in cancer management. A critical review.

1981 • 9 citations

Nutritional and immunological evaluations in cancer patients. Relationship to surgical infections

1980 • 9 citations

The manipulation of metabolism by drugs and nutrients.

1969 • 6 citations

Influence of pantothenic acid deficiency on the viability and growth of a rat fibrosarcoma.

1951 • 2 citations