Characterization of α1-adrenoceptor subtypes in prostate and prostatic urethra of rat, rabbit, dog and man

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Alpha 1-adrenergic receptor subtypes, inositol phosphates, and sources of cell Ca2+.

1988 • 566 citations

Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.

1991 • 401 citations

Benign Prostatic Hypertrophy

1983 • 330 citations

Identification, Quantification, and Localization of mRNA for Three Distinct Alpha₁Adrenergic Receptor Subtypes in Human Prostate

1993 • 317 citations

Comparison of alpha 1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101.

1988 • 268 citations

Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine.

1987 • 267 citations

The Present Role of Alpha-Adrenergic Blockers in the Treatment of Benign Prostatic Hypertrophy

1986 • 260 citations

5-Methyl-urapidil discriminates between subtypes of the α1-adrenoceptor

1988 • 208 citations

Subtypes of α1adrenoceptors in rat blood vessels

1990 • 141 citations

The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity.

1991 • 135 citations

Aspects on the physiology and pharmacology of the bladder and urethra

1982 • 118 citations

Identification of a single α₁‐adrenoceptor corresponding to the α_1A‐subtype in rat submaxillary gland

1989 • 110 citations

Pharmacologic characterization of cloned α1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype

1992 • 107 citations

Differentiation of alpha 1-adrenergic receptors linked to phosphatidylinositol turnover and cyclic AMP accumulation in rat brain.

1987 • 104 citations

Role of alpha-adrenergic blockers in the treatment of benign prostatic hyperplasia

1990 • 85 citations

Species heterogeneity of hepatic α1-adrenoceptors: α1A-, α1B- and α1C-subtypes

1992 • 51 citations

Autonomic Innervation of the Prostate

1983 • 33 citations

Binding characteristics of naftopidil and α1-adrenoceptor antagonists to prostatic α-adrenoceptors in benign prostatic hypertrophy

1992 • 32 citations

Binding and Functional Properties of Alpha ₁ Adrenoceptors and Area Density of Smooth Muscle in the Canine Prostate

1992 • 25 citations

International consultation on benign prostatic hyperplasia.

1994 • 24 citations

Pharmacological characterization of alpha adrenergic receptors in the young and old female rabbit urethra.

1991 • 22 citations

α‐ and β‐Adrenoceptors in Hypertension: Molecular Biology and Pharmacological Studies

1992 • 21 citations

Alpha-adrenoceptor inhibitors in the treatment of benign prostatic hyperplasia

1989 • 19 citations

[³H]Bunazosin, a Novel Selective Radioligand of Alpha₁Adrenoceptors in Human Prostates

1991 • 16 citations

Alpha-Blockers in the Treatment of Benign Prostatic Hypertrophy: Physiological Basis and Review of the Problem

1984 • 11 citations

Autoradiographic localization of α₁‐adrenoceptors in the dog prostate and urethra with ³H‐prazosin

1991 • 7 citations

Characterization of a newly synthesized radioligand [3H)-YM617 and its selectivity for α1-adrenoceptor subtypes in rabbit tissues

1992 • 4 citations

α1-Adrenoceptors in human prostate and aorta: Comparison of the receptor binding affinity of α1 antagonists

1992 • 4 citations

Subtypes of α1-adrenoceptors in prostatic urethra and prostate of rats, rabbits and dogs

1992 • 1 citations