Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

Hydration of Proteins and Polypeptides

1974 • 1,113 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

1990 • 709 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

1989 • 447 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Identification of the residues in human CD4 critical for the binding of HIV

1989 • 357 citations

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

1987 • 348 citations

Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4

1988 • 294 citations

Expression and function of CD4 in a murine T-cell hybridoma

1987 • 208 citations

Crystal structure and molecular interactions of tropomyosin

1979 • 141 citations

Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes.

1989 • 140 citations

Liquid-like movements in crystalline insulin

1988 • 129 citations

The structure of form I crystals of d-ribulose-1,5-diphosphate carboxylase

1975 • 106 citations

Molecular dynamics studied by analysis of the X-ray diffuse scattering from lysozyme crystals

1987 • 92 citations

Protein and carbohydrate structural analysis of a recombinant soluble CD4 receptor by mass spectrometry

1989 • 73 citations

Crystallization of a soluble form of the rat T-cell surface glycoprotein CD4 complexed with Fab from the W3/25 monoclonal antibody

1990 • 29 citations

Crystal forms of lamprey hemoglobin and crystalline transitions between ligand states

1968 • 22 citations

Structural features of CD4 required for binding to HIV.

1989 • 19 citations

The effect of polyethylene glycol on the growth and dissolution rates of a crystalline protein at high salt concentration. Phosphoglucomutase.

1986 • 17 citations