Involvement of the Kinin‐generating Cascade in Enhanced Vascular Permeability in Tumor Tissue

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

1986 • 6,585 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines.

1986 • 641 citations

Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report

1983 • 332 citations

The preparation and labeling of DTPA-coupled albumin

1982 • 329 citations

Use of oily contrast medium for selective drug targeting to tumor: enhanced therapeutic effect and X-ray image.

1984 • 283 citations

Selective targeting of anti-cancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium

1984 • 230 citations

Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: pronounced improvements in pharmacological properties

1985 • 221 citations

A LIPOPHILIC DERIVATIVE OF NEOCARZINOSTATIN A Polymer Conjugation of an Antitumor Protein Antibiotic*

1979 • 151 citations

A potent mercapto bi-product analogue inhibitor for human carboxypeptidase N

1981 • 150 citations

Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo.

1981 • 146 citations

Pathogenesis of Serratial Infection: Activation of the Hageman Factor-Prekallikrein Cascade by Serratial Protease

1984 • 129 citations

Purification and identification of [hydroxyprolyl3]bradykinin in ascitic fluid from a patient with gastric cancer.

1988 • 127 citations

Radioimmunoimaging and radioimmunotherapy

1983 • 116 citations

A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs

1985 • 104 citations

Protein tailoring for food and medical uses

1987 • 74 citations

Inhibition of vascular permeability changes in rats by captopril.

1982 • 49 citations

Tumor targeting by arterial administration of lipids: rabbit model with VX2 carcinoma in the liver.

1987 • 47 citations

Medial regression and its functional significance in tumor-supplying host arteries. A morphometric study of hepatic arteries in human livers with hepatocellular carcinoma

1987 • 46 citations

Activation of plasma kallikrein-kinin system and its significant role in pleural fluid accumulation of rat carrageenin-induced pleurisy

1983 • 46 citations

Pepstatin, an inhibitor of leukokinin formation and ascitic fluid accumulation.

1975 • 36 citations

Studies on leukokinins—III

1972 • 25 citations

Enhancement of Vascular Permeability Upon Serratial Infection: Activation of Hageman Factor — Kallikrein — Kinin Cascade

1986 • 10 citations