A Bifunctional Enzyme Catalyzes the First Two Steps inN-Acetylneuraminic Acid Biosynthesis of Rat Liver

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver staining

1985 • 1,359 citations

Aberrant Glycosylation In Tumors And Tumor-Associated Carbohydrate Antigens

1989 • 1,083 citations

An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.

1992 • 805 citations

CELL ADHESION MOLECULES: Implications for a Molecular Histology

1991 • 707 citations

Diversity in the sialic acids

1992 • 590 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Hypomethylation of ras oncogenes in primary human cancers

1983 • 507 citations

NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES

1969 • 382 citations

Glycosciences: Status and Perspectives

2002 • 382 citations

Biosynthesis of a nonphysiological sialic acid in different rat organs, using N-propanoyl-D-hexosamines as precursors.

1992 • 321 citations

THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER

1964 • 310 citations

Microbial recognition of target-cell glycoconjugates

1995 • 309 citations

Helix-turn-helix, zinc-finger, and leucine-zipper motifs for eukaryotic transcriptional regulatory proteins

1989 • 306 citations

Biology of the Sialic Acids

1995 • 302 citations

A Bifunctional Enzyme Catalyzes the First Two Steps in N-Acetylneuraminic Acid Biosynthesis of Rat Liver

1997 • 295 citations

Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials.

1994 • 218 citations

Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.

1988 • 187 citations

Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.

1990 • 180 citations

Biosynthetic Modulation of Sialic Acid-dependent Virus-Receptor Interactions of Two Primate Polyoma Viruses

1995 • 168 citations

The Phage T4-coded DNA Replication Helicase (gp41) Forms a Hexamer upon Activation by Nucleoside Triphosphate

1995 • 133 citations

Dissociation of Enzyme Oligomers: A Mechanism for Allosteric Regulation

1994 • 133 citations

Role of charge and hydration in effects of polysialic acid on molecular interactions on and between cell membranes.

1994 • 125 citations

Molecular Cloning and Identification of -Acyl-D-glucosamine 2-Epimerase from Porcine Kidney as a Renin-binding Protein

1996 • 116 citations

Enzymic synthesis of N-acetyl-D-mannosamine

1958 • 100 citations

Structural analysis and functional role of the carbohydrate component of somatostatin receptors.

1991 • 94 citations

The Isolation and Characterization of cDNA Encoding the Mouse Bifunctional ATP Sulfurylase-Adenosine 5′-Phosphosulfate Kinase

1995 • 92 citations

Review

1996 • 82 citations

Biosynthesis of N‐Acetylneuraminic Acid in Morris Hepatomas

1973 • 77 citations

Evidence that functional erythrocyte-type glucose transporters are oligomers.

1991 • 73 citations

Cancer-associated mucins and mucin-type glycoproteins

1991 • 67 citations

Sialic acid metabolism in sialuria fibroblasts.

1991 • 66 citations

ENZYMATIC PHOSPHORYLATION OF N-ACETYL-D-MANNOSAMINE

1961 • 62 citations

Specific antisera produced by direct immunization with slices of polyacrylamide gel containing small amounts of protein

1982 • 61 citations

Identification of the metabolic defect in sialuria

1989 • 60 citations

Asn-linked oligosaccharides in lectin-resistant tumor-cell mutants with varying metastatic potential

1986 • 58 citations

Intrinsic Activity and Stability of Bifunctional Human UMP Synthase and Its Two Separate Catalytic Domains, Orotate Phosphoribosyltransferase and Orotidine-5′-phosphate Decarboxylase

1996 • 48 citations

Channeling between the active sites of formiminotransferase-cyclodeaminase. Binding and kinetic studies.

1985 • 41 citations

The Sialic Acids

1966 • 39 citations

Uridine diphosphate N-acetyl-d-glucosamine 2-epimerase from rat liver

1972 • 37 citations

Regulatory role of adenosine triphosphate on hog kidney N-acetyl-D-glucosamine 2-epimerase

1970 • 35 citations

Optimized deglycosylation of glycoproteins by peptide-N4-(N-acetyl-β-glucosaminyl)-asparagine amidase fromFlavobacterium meningosepticum

1990 • 35 citations

Purification and properties of -N- 2′-epimerase from rat liver

1973 • 34 citations

Subcellular localization and tissue distribution of sialic acid precursor-forming enzymes

1983 • 33 citations

Sialic Acid Content of Plasminogen 2 Glycoforms as a Regulator of Fibrinolytic Activity

1995 • 32 citations

Kinetic characterization of N-acetyl-D-glucosamine kinase from rat liver and kidney

1980 • 30 citations

Determination of cytidine 5′-monophospho-N-acetylneuraminic acid pool size in cell culture scale using high-performance anion-exchange chromatography with pulsed amperometric detection

1996 • 22 citations

Inhibition of the biosynthesis ofN-acetylneuraminic acid by metal ions and seleniumin vitro

1992 • 17 citations