Activation of protein kinase C induces differentiation in the human T-lymphoblastic cell line MOLT-3

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

[The role of protein kinase C in cell surface signal transduction and tumor promotion].

1986 • 508 citations

Terminal deoxynucleotidyl transferase as a hematopoietic cell marker

1979 • 504 citations

Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.

1982 • 417 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

1985 • 387 citations

Competitive inhibition by diacylglycerol of specific phorbol ester binding.

1984 • 306 citations

Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.

1984 • 283 citations

Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters

1980 • 274 citations

Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.

1984 • 266 citations

Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.

1985 • 218 citations

T‐Lymphocyte Activation: The Role of Protein Kinase C and the Bifurcating Inositol Phospholipid Signal Transduction Pathway

1987 • 203 citations

Protein kinase activity associated with a phorbol ester receptor purified from mouse brain.

1983 • 175 citations

Identification of high-affinity phorbol ester receptor in cytosol of EL4 thymoma cells: requirement for calcium, magnesium, and phospholipids.

1983 • 157 citations

The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies.

1987 • 153 citations

Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.

1981 • 144 citations

A possible role of protein kinase C in signal-induced lysosomal enzyme release

1983 • 128 citations

Phorbol esters induce differentiation in human malignant T lymphoblasts

1980 • 121 citations

Possible mechanism of phorbol diester-induced maturation of human promyelocytic leukemia cells.

1984 • 110 citations

Translocation of protein kinase C in human leukemia cells susceptible or resistant to differentiation induced by phorbol 12-myristate 13-acetate.

1986 • 101 citations

Synergistic Effect of a Tumor-Promoting Phorbol Ester and a Hypoglycemic Sulfonylurea upon Insulin Release^*

1983 • 54 citations

Specific protein phosphorylation in human promyelocytic HL-60 leukemia cells susceptible or resistant to induction of cell differentiation by phorbol-12-myristate-13-acetate.

1985 • 44 citations

Effects of phorbol ester on translocation and down-regulation of protein kinase C and phosphorylation of endogenous proteins in human acute myeloid leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.

1987 • 37 citations

Induction of human malignant T‐lymphoblastic cell lines MOLT‐3 and jurkat by 12‐O‐tetradecanoylphorbol‐13‐acetate: Biochemical, physical, and morphological characterization

1981 • 37 citations

Purification of terminal deoxynucleotidyltransferase by oligonucleotide affinity chromatography.

1978 • 26 citations

Modulation of human T-cell differentiation markers by 12-O-tetradecanoylphorbol-13-acetate.

1981 • 8 citations

Phorbol Ester Receptors and the Induction of Differentiation in the Human T Lymphoblastic Cell Line MOLT-3

1988 • 7 citations