Duplications and deletions of the human IGHC locus: evolutionary implications

Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing γ, ε and α genes

1982 • 421 citations

Inherited deletion of immunoglobulin heavy chain constant region genes in normal human individuals

1982 • 166 citations

Duplication and deletion in the human immunoglobulin ϵ genes

1982 • 146 citations

Complete physical map of the human immunoglobulin heavy chain constant region gene complex.

1989 • 109 citations

Restriction fragment length polymorphisms associated with immunoglobulin C gamma genes reveal linkage disequilibrium and genomic organization.

1983 • 99 citations

Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene

1981 • 91 citations

HLA-DR and -DQ gene polymorphism in West Africans is twice as extensive as in north European Caucasians: evolutionary implications.

1991 • 65 citations

Gene deletions in the human immunoglobulin heavy chain constant region locus: molecular and immunological analysis.

1991 • 56 citations

Novel families of interspersed repetitive elements from the human genome

1990 • 54 citations

A multigene deletion in the human IGH constant region locus involves highly homologous hot spots of recombination

1989 • 45 citations

Definition of the RFLP alleles in the human immunoglobulin IGHG gene locus

1988 • 44 citations

Molecular and serologic analysis of IgG1 deficiency caused by new forms of the constant region of the Ig H chain gene deletions.

1989 • 39 citations

A multigene deletion within the immunoglobulin heavy-chain region.

1985 • 38 citations

Pulsed-field gel analysis of human immunoglobulin heavy-chain constant region gene deletions reveals the extent of unmapped regions within the locus

1989 • 33 citations

Molecular analysis of the T17 immunoglobulin CH multigene deletion (del A1-GP-G2-G4-E)

1994 • 30 citations

Variability of the immunoglobulin heavy chain constant region locus: a population study

1995 • 25 citations

Gene deletions within the human immunoglobulin heavy chain constant region gene cluster.

1989 • 25 citations

Detection of immunoglobulin genes in individuals with immunoglobulin class or subclass deficiency. Evidence for a pretranslational defect.

1986 • 23 citations

Pulsed-field electrophoresis screening for immunoglobulin heavy-chain constant-region (IGHC) multigene deletions and duplications.

1991 • 23 citations

Ig H chain variable and C region genes in common variable immunodeficiency. Characterization of two new deletion haplotypes.

1991 • 19 citations

Inheritance of a Large Deletion within the Human Immunoglobulin Heavy Chain Constant Region Gene Complex and Immunological Implications

1989 • 18 citations

Multiple levels of analysis of an IGHG4 gene deletion

1990 • 17 citations

Structural and immunologic analysis of gene triplications in the Ig heavy chain constant region locus.

1994 • 17 citations

BamHI and SacI RFLPs of the human immunoglobulin IGHG genes with reference to the Gm polymorphism in African people

1989 • 17 citations

The influence of gene deletions and duplications within the IGHC locus on serum immunoglobulin subclass levels

1995 • 15 citations

A method for two-dimensional DNA electrophoresis (2D-DE): Application to the immunoglobulin heavy chain variable region

1989 • 15 citations

A multigene deletion in the immunoglobulin heavy chain region in a highly atopic individual

1990 • 11 citations