Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition

The Hippocampus as a Cognitive Map

1978 • 8,087 citations

Information theory and statistics

1959 • 7,634 citations

Place navigation impaired in rats with hippocampal lesions

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1960 • 5,766 citations

The Psychology of Learning and Motivation

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The effect of emotion on cue utilization and the organization of behavior.

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Spatial localization does not require the presence of local cues

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The Hippocampus as a Cognitive Map

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Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

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1983 • 1,877 citations

Components of attention.

1971 • 1,688 citations

Dopamine (3-hydroxytyramine) and brain function.

1966 • 1,401 citations

Adipsia and Aphagia after 6‐Hydroxydopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,271 citations

The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

1982 • 1,128 citations

Neurobiology of learning and memory

1985 • 1,024 citations

Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli.

1981 • 974 citations

Mechanisms of Animal Discrimination Learning

1972 • 952 citations

Nonrepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli

1981 • 872 citations

Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal

1983 • 728 citations

Depletion of brain noradrenaline and dopamine by 6‐hydroxydopamine

1971 • 535 citations

Application of high performance liquid chromatography with electrochemical detection to neurochemical analysis: measurement of catecholamines, serotonin and metabolites in rat brain

1981 • 524 citations

Attention and arousal, cognition and performance

1982 • 509 citations

Cognitive Neurochemistry

1989 • 483 citations

A selective mnemonic role for the hippocampus in monkeys: memory for the location of objects

1988 • 445 citations

The Amygdaloid Complex

1948 • 390 citations

Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. I. Acutely presented stressful and nonstressful stimuli

1987 • 374 citations

Context and conditioning: A place for space

1980 • 372 citations

Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: Pharmacological and behavioral studies

1988 • 345 citations

Functional Studies of the Central Catecholamines

1982 • 344 citations

Interaction of norepinephrine with cerebrocortical activity evoked by stimulation of somatosensory afferent pathways in the rat☆

1980 • 320 citations

Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi on performance of a 5-choice serial reaction time task in rats: Implications for theories of selective attention and arousal

1989 • 318 citations

The action of norepinephrine in the rat hippocampus. IV. The effects of locus coeruleus stimulation on evoked hippocampal unit activity

1976 • 304 citations

Stress and Catecholamines

1975 • 250 citations

Modulation of rat brain α- and β-adrenergic receptor populations by lesions of the dorsal noradrenergic bundle

1980 • 246 citations

Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: New evidence for central dopaminergic-noradrenergic interactions

1987 • 242 citations

Behavioral functions of locus coeruleus derived from cellular attributes

1985 • 232 citations

Chlordiazepoxide, an anxiolytic benzodiazepine, impairs place navigation in rats

1987 • 213 citations

Memory Formation: Evidence for a Specific Neurochemical System in the Amygdala

1977 • 195 citations

Activation-induced restoration of sensorimotor functions in rats with dopamine-depleting brain lesions.

1976 • 180 citations

Effects of locus coeruleus lesions on auditory, long-latency, event- related potentials in monkey

1989 • 179 citations

Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. II. Adaptation to chronically presented stressful stimuli

1987 • 166 citations

The hippocampus and conditioning to contextual cues.

1987 • 158 citations

The Neuropsychology of Anxiety

1983 • 151 citations

Increase of corticotropin-releasing factor staining in rat paraventricular nucleus neurones by depletion of hypothalamic adrenaline

1984 • 146 citations

Neurotransmitters and memory: Role of cholinergic, serotonergic, and noradrenergic systems.

1987 • 142 citations

The hippocampus and conditioning to contextual cues.

1987 • 140 citations

Anxiety and the Amygdala: Pharmacological and Anatomical Analysis of the Fear-Potentiated Startle Paradigm

1988 • 139 citations

Single cell responses in cat visual cortex to visual stimulation during iontophoresis of noradrenaline

1982 • 135 citations

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

1985 • 131 citations

Enhanced behavioral conditioning to context and impaired behavioral and neuroendocrine responses to conditioned stimuli following ceruleocortical noradrenergic lesions: support for an attentional hypothesis of central noradrenergic function

1990 • 118 citations

Neurotransmitters and memory: Role of cholinergic, serotonergic, and noradrenergic systems.

1987 • 118 citations

The effects of lesions to ascending noradrenergic neurons on discrimination learning and performance in the rat

1983 • 116 citations

The effects of central catecholamine depletions on spatial learning in rats

1983 • 106 citations

Compensatory Increase in Tyrosine Hydroxylase Activity in Rat Brain After Intraventricular Injections of 6-Hydroxydopamine

1980 • 102 citations

The role of ventral bundle noradrenergic neurones in sensory components of sexual behaviour and coitus-induced pseudopregnancy

1980 • 93 citations

Dorsal noradrenergic bundle and selective attention in the rat.

1980 • 85 citations

The locus coeruleus and cognitive function: Attempts to relate noradrenergic enhancement of signal/noise in the brain to behavior

1985 • 81 citations

Lack of task specificity and absence of posttraining effects of atropine on learning.

1986 • 79 citations

Cortical noradrenaline depletion eliminates sparing of spatial learning after neonatal frontal cortex damage in the rat

1982 • 72 citations

Role of activation and sensory stimuli in recovery from lateral hypothalamic damage in the cat.

1978 • 72 citations

Cholinergic blockade in the rat impairs strategy selection but not learning and retention of nonspatial visual discrimination problems in a swimming pool.

1988 • 71 citations

Reversal of behavioral depression by infusion of an alpha-2 adrenergic agonist into the locus coeruleus

1986 • 71 citations

Lack of task specificity and absence of posttraining effects of atropine on learning.

1986 • 69 citations

Functional hypotheses of the coeruleocortical noradrenergic projection: A review of recent experimentation and theory

1985 • 66 citations

Effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on visual discrimination acquisition, performance and reversal in the rat

1989 • 62 citations

Cholinergic blockade in the rat impairs strategy selection but not learning and retention of nonspatial visual discrimination problems in a swimming pool.

1988 • 58 citations

Acute homeostatic imbalances reinstate sensorimotor dysfunctions in rats with lateral hypothalamic lesions.

1979 • 57 citations

Dissociable effects of lesions to the dorsal or ventral noradrenergic bundle on the acquisition, performance, and extinction of aversive conditioning.

1987 • 55 citations

Dissociable effects of lesions to the dorsal or ventral noradrenergic bundle on the acquisition, performance, and extinction of aversive conditioning.

1987 • 55 citations

The effects of concurrent manipulations of cholinergic and noradrenergic systems on neocortical EEG and spatial learning

1990 • 50 citations

Stress related recovery from lateral hypothalamic aphagia

1976 • 49 citations

New Considerations in the Neuropsychology of Motivated Behaviors

1977 • 49 citations

Effects of neonatal forebrain noradrenaline depletion on recovery from brain damage: Performance on a spatial navigation task as a function of age of surgery and postsurgical housing

1986 • 46 citations

Changes in body weight and food-related behaviour induced by destruction of the ventral or dorsal noradrenergic bundle in the rat

1983 • 44 citations

Functional evidence for postsynaptic supersensitivity of central noradrenergic receptors after denervation

1975 • 44 citations

Lesions of the dorsal noradrenergic bundle simultaneously enhance and reduce responsivity to novelty in a food preference test

1988 • 38 citations

Neonatal hemidecortication or frontal cortex ablation produces similar behavioral sparing but opposite effects on morphogenesis of remaining cortex.

1983 • 30 citations

Enhanced neophobia but normal plasma corticosterone levels in rats with dorsal noradrenergic bundle lesions

1982 • 28 citations

Neurochemical basis of the dorsal bundle extinction effect

1979 • 26 citations

Alleviation of response suppression to conditioned aversive stimuli by lesions of the dorsal noradrenergic bundle

1984 • 25 citations

Neonatal hemidecortication or frontal cortex ablation produces similar behavioral sparing but opposite effects on morphogenesis of remaining cortex.

1983 • 23 citations

The effects of dorsal bundle lesions on serial and trace conditioning

1983 • 22 citations

Role for lateral tegmental noradrenergic neurons in the vasopressin response to hypertonic saline

1983 • 20 citations

The central nervous system and behavior. Transactions of the third (1960) conference

1962 • 20 citations

Noradrenaline- and time-dependent changes in neocortical α2- and β1-adrenoceptor binding in dorsal noradrenergic bundle-lesioned rats

1987 • 18 citations

Deleted Work

1955 • 0 citations