The Thymus: Its Influence on Recognition of “Self Major Histocompatibility Antigens” by T Cells and Consequences for Reconstitution of Immunodeficiency

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

Biology of the Mouse Histocompatibility-2 Complex

1975 • 1,145 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

The somatic generation of immune recognition

1971 • 974 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

1974 • 832 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 611 citations

Current concepts of the immunological function of the thymus.

1967 • 577 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

Cellular and Humoral Aspects of the Hypersensitive States

1959 • 549 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

1975 • 479 citations

In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice.

1975 • 454 citations

HL-A, IMMUNE-RESPONSE GENES, AND DISEASE

1974 • 449 citations

CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES

1973 • 431 citations

HLA and disease

1977 • 430 citations

Tracing of cells of the avian thymus through embryonic life in interspecific chimeras.

1975 • 409 citations

Y-antigen killing by T cells of women is restricted by HLA

1977 • 326 citations

Purification and Biological Activity of Thymosin, a Hormone of the Thymus Gland

1972 • 308 citations

H-2 Dependence of Co-Operation Between T and B Cells in Vivo

1972 • 285 citations

HLA restriction of cell-mediated lysis of influenza virus-infected human cells

1977 • 274 citations

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

1978 • 268 citations

Functional Specificity of Thymus-Dependent Lymphocytes

1977 • 256 citations

PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY

1963 • 234 citations

THE ROLE OF PRODUCTS OF THE HISTOCOMPATIBILITY GENE COMPLEX IN IMMUNE RESPONSES

1975 • 223 citations

Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymus

1978 • 219 citations

Appearance of T-cell Markers in Bone Marrow Rosette-Forming Cells after Incubation with Thymosin, a Thymic Hormone

1971 • 195 citations

IMPLANTATION OF A FŒTAL THYMUS, RESTORING IMMUNOLOGICAL COMPETENCE IN A PATIENT WITH THYMIC APLASIA (DiGEORGE'S SYNDROME)

1968 • 188 citations

The Thymus and the Cellular Basis of Immunity

1969 • 188 citations

Severe combined immunodeficiency disease. Characterization of the disease and results of transplantation.

1977 • 177 citations

Macrophage‐Dependent Response of Immune Human T Lymphocytes to PPD In Vitro Influence of HLA‐D Histocompatibility

1977 • 146 citations

Homograft Sensitivity: An Expression of the Immunologic Origins and Consequences of Individuality

1959 • 136 citations

Cellular and humoral aspects of the hypersensitive states : a symposium held at the New York academy of medicine

1959 • 110 citations

Severe Combined Immunodeficiency Disease

1977 • 104 citations

Human cell-mediated cytotoxicity against modified target cells is restricted by HLA

1977 • 103 citations

Virus and trinitrophenol hapten-specific T-cell-mediated cytotoxicity against H-2 incompatible target cells.

1976 • 93 citations

SUCCESSFUL FETAL LIVER TRANSPLANTATION IN A CHILD WITH SEVERE COMBINED IMMUNODEFICIENCY

1975 • 87 citations

Effect of Neonatal Thymectomy on the Immune Response in the Chicken

1962 • 86 citations

Correction of Severe Combined Immunodeficiency by Fetal Liver Cells

1976 • 79 citations

Virus-specific T-cell-mediated cytotoxicity across the H–2 barrier to virus-altered alloantigen

1976 • 74 citations

Thymus Transplantation

1973 • 73 citations

H-2 restriction of virus-specific cytotoxicity across the H-2 barrier. Separate effector T-cell specificities are associated with self-H-2 and with the tolerated allogeneic H-2 in chimeras.

1976 • 73 citations

Products of the major histocompatibility complex and their relationship to the immune response

1976 • 71 citations

Cytotoxic T lymphocytes recognise allogeneic tolerated TNP-conjugated cells

1976 • 69 citations

ACTIVITY OF HOST-DERIVED T CELLS WHICH DIFFERENTIATE IN NUDE MICE GRAFTED WITH CO-ISOGENIC OR ALLOGENEIC THYMUSES

1974 • 69 citations

Cellular Immunity Against Rous Sarcomas of Chickens. Preferential Reactivity Against Autochthonous Target Cells as Determined by Lymphocyte Adherence and Cytotoxicity Tests In Vitro

1974 • 56 citations

GENETIC CONTROL OF LYMPHOCYTE INTERACTIONS AND DIFFERENTIATION

1976 • 55 citations

Thymic activity in severe combined immunodeficiency diseases.

1977 • 53 citations

Rationale for combined use of fetal liver and thymus for immunological reconstitution in patients with variants of severe combined immunodeficiency

1977 • 44 citations

COMPLETE RESTORATION OF BURSA-DEPENDENT IMMUNE SYSTEM AFTER TRANSPLANTATION OF SEMIALLOGENEIC STEM CELLS INTO IMMUNODEFICIENT CHICKS

1974 • 42 citations

Cell-Mediated Immune Response to Lymphocytic Choriomeningitis and Vaccinia Virus in Rats

1977 • 41 citations

Immune Response of Mice to Thy-1.1 Antigen: Genetic Control by Alleles at the Ir-5 Locus Loosely Linked to the H-2 Complex

1974 • 34 citations

GRAFTING OF FETAL THYMUS AND HEMATOPOIETIC TISSUE IN INFANTS WITH IMMUNE DEFICIENCY SYNDROMES1

1973 • 33 citations

[HLA and disease].

1978 • 27 citations

Variation in T and B Cell Deficiency in Different Mouse Allogeneic Radiation Chimeras

1974 • 22 citations

Studies of the immunological capacity of germ-free mouse radiation chimeras

1973 • 19 citations

Abnormal Immune Mechanism in Allogeneic Radiation Chimeras

1965 • 18 citations

Studies of the immunological capacity of germ-free mouse radiation chimeras

1974 • 18 citations

Origins of Lymphocyte Diversity.

1978 • 15 citations

DIFFERENTIATED INTEREST RATE AND KALDOR‐PASINETTI PARADOXES

1976 • 10 citations

Immunologic Reconstitution with Fetal Tissue

1976 • 7 citations

Defective Thymus Development: A Cause of Combined Immunodeficiency

1975 • 6 citations

Deleted Work

1955 • 0 citations