Production of IL-5 and granulocyte-macrophage colony-stimulating factor by naive human mast cells activated by high-affinity IgE receptor ligation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

Allergy: Principles and Practice.

1991 • 1,717 citations

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

1996 • 1,382 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

1991 • 841 citations

Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.

1991 • 676 citations

Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation.

1993 • 561 citations

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia.

1994 • 498 citations

Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture

1992 • 436 citations

Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)/cachectin by mouse mast cells stimulated via the Fc epsilon RI. A mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses.

1991 • 369 citations

CD4⁺T-Lymphocytes and Interleukin-5 Mediate Antigen-induced Eosinophil Infiltration into the Mouse Trachea

1992 • 353 citations

IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner.

1990 • 328 citations

Heterogeneity of human mast cells based on cytokine content.

1995 • 308 citations

Immediate and Late Airway Response of Allergic Rhinitis Patients to Segmental Antigen Challenge: Characterization of Eosinophil and Mast Cell Mediators

1991 • 281 citations

Mechanisms of Eosinophil Recruitment

1993 • 274 citations

Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.

1993 • 264 citations

Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

1992 • 238 citations

Modulation and induction of eosinophil chemotaxis by granulocyte- macrophage colony-stimulating factor and interleukin-3

1991 • 230 citations

IL-5 Is the Predominant Eosinophil-active Cytokine in the Antigen-induced Pulmonary Late-phase Reaction

1993 • 194 citations

Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody.

1995 • 190 citations

Detection of Cytokines and Their Cell Sources in Bronchial Biopsy Specimens From Asthmatic Patients

1994 • 166 citations

The Pathobiology of Bronchial Asthma

1992 • 154 citations

IgE-dependent expression of mRNA for IL-4 and IL-5 in human lung mast cells.

1995 • 149 citations

Late Phase Allergic Reactions

1983 • 149 citations

Mast cells modulate allergic pulmonary eosinophilia in mice.

1995 • 147 citations

T Cells Are the Principal Source of Interleukin-5 mRNA in Allergen-induced Rhinitis

1993 • 142 citations

In vivo priming of platelet-activating factor-induced eosinophil chemotaxis in allergic asthmatic individuals

1992 • 131 citations

Secretion of the eosinophil‐active cytokines interleukin‐5, granulocyte/macrophage colonystimulating factor and interleukin‐3 by bronchoalveolar lavage CD4⁺ and CD8⁺ T cell lines in atopics asthmatics, and atopic and nonatopic controls

1995 • 116 citations

Evaluation of a radioimmunoassay for histamine measurement in biologic fluids

1988 • 115 citations

Anti-IL-5 monoclonal antibody inhibits allergic late phase bronchial eosinophilia in guinea pigs: a therapeutic approach

1992 • 112 citations

Eosinophil transendothelial migration induced by cytokines. II. Potentiation of eosinophil transendothelial migration by eosinophil-active cytokines.

1994 • 103 citations

T Cells Are Necessary for Th2 Cytokine Production and Eosinophil Accumulation in Airways of Antigen-Challenged Allergic Mice

1995 • 103 citations

Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma.

1995 • 96 citations

Human lung mast cell IL-5 gene and protein expression: temporal analysis of upregulation following IgE-mediated activation.

1995 • 65 citations

Purification of human basophils and mast cells by multistep separation technique and mAb to CDw17 and

1995 • 54 citations

Inhibition of the growth of IL-3-dependent mast cells from murine bone marrow by recombinant granulocyte macrophage-colony-stimulating factor.

1989 • 48 citations

GM-CSF regulates human eosinophil responses to F-Met peptide and platelet activating factor.

1993 • 43 citations

Appearance of granulocyte-macrophage colony-stimulating factor activity at allergen-challenged cutaneous late-phase reaction sites.

1993 • 37 citations

Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture

1992 • 33 citations

T cell regulation of human B cell proliferation and differentiation. Regulatory influences of CD45R+ and CD45R- T4 cell subsets.

1989 • 33 citations

Enhanced detection of human IL-5 in biological fluids utilizing murine monoclonal antibodies which delineate distinct neutralizing epitopes

1994 • 32 citations

Detection of interleukin-5 messenger RNA and interleukin-5 protein in bronchial biopsies from asthma by nonradioactive in situ hybridization and immunohistochemistry

1994 • 19 citations

In vivo priming of platelet-activating factor-induced eosinophil chemotaxis in allergic asthmatic individuals

1992 • 17 citations

Modulation and induction of eosinophil chemotaxis by granulocyte- macrophage colony-stimulating factor and interleukin-3

1991 • 17 citations